@article{WeisshaarGhanamIrsenetal.2018, author = {Maria Weisshaar and Jamal Ghanam and Stephan Irsen and Julio Reinecke and Peter Wehling}, title = {Inflammatory molecules are cell-to-cell transported by exosomes in the anti-inflammatory human autologous conditioned serum}, series = {Journal of Extracellular Vesicles}, volume = {7}, number = {sup1}, publisher = {Taylor \& Francis}, issn = {2001-3078}, pages = {142}, year = {2018}, abstract = {Background: Local injection of autologous conditioned serum (ACS) is a well-known therapy for inflammatory diseases (IDs). While patients’ blood is incubated to generate ACS (with subsequent centrifugation), immune cells produce high amounts of growth factors and cytokines. This include, amongst others, interleukin-1 receptor antagonist (IL-1ra), interleukins 6 and 10, tumour necrosis factor alpha (TNF-α) and transforming growth factor beta 1 (TGF-β1). The aim of this study was to analyse exosomes release into ACS as well as their cytokine cargo.}, language = {en} }