@article{PfutznerKuntHohbergetal.2004, author = {A. Pfutzner and T. Kunt and C. Hohberg and A. Mondok and S. Pahler and T. Konrad and G. Lubben and T. Forst}, title = {Fasting Intact Proinsulin Is a Highly Specific Predictor of Insulin Resistance in Type 2 Diabetes}, series = {Diabetes Care}, volume = {27}, number = {3}, publisher = {American Diabetes Association}, address = {Alexandria, Va.}, issn = {0149-5992}, doi = {10.2337/diacare.27.3.682}, pages = {682 -- 687}, year = {2004}, abstract = {OBJECTIVE—In later stages of type 2 diabetes, proinsulin and proinsulin-like molecules are secreted in increasing amounts with insulin. A recently introduced chemiluminescence assay is able to detect the uncleaved “intact” proinsulin and differentiate it from proinsulin-like molecules. This investigation explored the predictive value of intact proinsulin as an insulin resistance marker.}, language = {en} }