@phdthesis{Breuer2020,
  author    = {Breuer, Christian},
  title     = {Design and Synthesis of Covalent Peptidomimetic Inhibitors for Human Cysteine Cathepsins},
  organization    = {Rheinische Friedrich-Wilhelms-Universit{\"a}t Bonn},
  url       = {https://nbn-resolving.org/urn:nbn:de:hbz:5-57228},
  institution = {Fachbereich Angewandte Naturwissenschaften},
  pages     = {VIII, 294},
  year      = {2020},
  abstract  = {The present thesis elucidates the development of (i) a series of small molecule inhibitors reacting in a covalent-irreversible manner with the targeted proteases and (ii) a fluorescently labeled activity-based probe as a pharmacological tool compound for investigation of specific functions of the mentioned enzymes in vitro. Herein, the rational design, organic synthesis and quantitative structure-activity-relationships are described extensively.},
  language  = {en}
}