TY  - CHAP
A1  - El Khaldi-Hansen, Basma
A1  - El-Sayed, Fatma
A1  - Schipper, Dorothee
A1  - Tobiasch, Edda
A1  - Witzleben, Steffen
A1  - Schulze, Margit
T1  - Functionalized 3D Scaffolds for Templatemediated Biomineralization in Bone Regeneration
T2  - Rahman, Anjum (Eds.): Frontiers in Stem Cell and Regenerative Medicine Research, Volume 5
N2  - Three-dimensional scaffolds are known to directly influence proliferation and differentiation of mesenchymal stem cells into bone tissue due to their properties such as stiffness and topography. While conventional methods for chemical induction of differentiation processes are based on incorporation of growth factors and/or cytokines via blending or adhesion onto the scaffold surfaces, novel approaches use template-mediated biomineralization to mimic the stimuli stem cells receive in their natural niche. This chapter summarizes recent progresses in guided bone tissue engineering with particular focus on design and functionality of three dimensional scaffolds, chemical templates and promising approaches for the corresponding cellbased approaches for future therapies.
KW  - stem cells
KW  - Tissue engineering
KW  - Biomineralization
KW  - Bone
KW  - Scaffolds
KW  - Template-mediation
Y1  - 2017
UR  - https://pub.h-brs.de/frontdoor/index/index/docId/3365
SN  - 978-1-68108-475-6
SP  - 130
EP  - 178
PB  - Bentham Science Publishers
ER  -