@article{NeffLueckGindtetal.2024, author = {Andr{\´e} Neff and Rebecca L{\"u}ck and M{\´e}lanie Gindt and Uwe Deppenmeier}, title = {Das untersch{\"a}tzte biotechnologische Potenzial der Darmmikrobiota}, series = {BIOspektrum}, volume = {30}, number = {1}, publisher = {Springer}, issn = {0947-0867}, doi = {10.1007/s12268-024-2087-z}, url = {https://nbn-resolving.org/urn:nbn:de:hbz:1044-opus-78255}, pages = {52 -- 54}, year = {2024}, abstract = {The human gut microbiota harbors untapped potential for biotechnological applications. Within the phylum of Bacteroidota, Phocaeicola vulgatus stands out as a promising candidate for sustainable production of key platform chemicals like succinate. However, genetic engineering of Phocaeicola sp. remains challenging due to its intricate molecular landscape. This study lays the groundwork for manipulating the central carbon pathways in Phocaeicola vulgatus, offering insights into overcoming genetic hurdles for increased succinate yields.}, language = {de} }