TY - JOUR U1 - Wissenschaftlicher Artikel A1 - Breuch, René A1 - Klein, Daniel A1 - Moers, Cassandra A1 - Siefke, Eleni A1 - Wickleder, Claudia A1 - Kaul, Peter T1 - Development of Gold Nanoparticle-Based SERS Substrates on TiO2-Coating to Reduce the Coffee Ring Effect JF - Nanomaterials N2 - Hydrophilic surface-enhanced Raman spectroscopy (SERS) substrates were prepared by a combination of TiO2-coatings of aluminium plates through a direct titanium tetraisopropoxide (TTIP) coating and drop coated by synthesised gold nanoparticles (AuNPs). Differences between the wettability of the untreated substrates, the slowly dried Ti(OH)4 substrates and calcinated as well as plasma treated TiO2 substrates were analysed by water contact angle (WCA) measurements. The hydrophilic behaviour of the developed substrates helped to improve the distribution of the AuNPs, which reflects in overall higher lateral SERS enhancement. Surface enhancement of the substrates was tested with target molecule rhodamine 6G (R6G) and a fibre-coupled 638 nm Raman spectrometer. Additionally, the morphology of the substrates was characterised using scanning electron microscopy (SEM) and Raman microscopy. The studies showed a reduced influence of the coffee ring effect on the particle distribution, resulting in a more broadly distributed edge region, which increased the spatial reproducibility of the measured SERS signal in the surface-enhanced Raman mapping measurements on mm scale. KW - coffee ring effect KW - SERS KW - AuNPs KW - TiO2-coatings KW - Raman spectroscopy Y1 - 2022 UN - https://nbn-resolving.org/urn:nbn:de:hbz:1044-opus-61306 SN - 2079-4991 SS - 2079-4991 U6 - https://doi.org/10.3390/nano12050860 DO - https://doi.org/10.3390/nano12050860 PM - 35269348 VL - 12 IS - 5 SP - 16 S1 - 16 PB - MDPI ER -