Inflammatory molecules are cell-to-cell transported by exosomes in the anti-inflammatory human autologous conditioned serum

  • Background: Local injection of autologous conditioned serum (ACS) is a well-known therapy for inflammatory diseases (IDs). While patients’ blood is incubated to generate ACS (with subsequent centrifugation), immune cells produce high amounts of growth factors and cytokines. This include, amongst others, interleukin-1 receptor antagonist (IL-1ra), interleukins 6 and 10, tumour necrosis factor alpha (TNF-α) and transforming growth factor beta 1 (TGF-β1). The aim of this study was to analyse exosomes release into ACS as well as their cytokine cargo.

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Document Type:Conference Object
Parent Title (English):ISEV 2018 abstract book
Parent Title (English):Journal of Extracellular Vesicles
First Page:142
Publisher:Taylor & Francis
Date of first publication:2018/05/04
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Dewey Decimal Classification (DDC):500 Naturwissenschaften und Mathematik / 570 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Entry in this database:2018/05/04