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Synthesis and kinetic evaluation of ethyl acrylate and vinyl sulfone derived inhibitors for human cysteine cathepsins

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Metadaten
Document Type:Article
Language:English
Author:Christian Breuer, Carina Lemke, Janina Schmitz, Ulrike Bartz, Michael Gütschow
Parent Title (English):Bioorganic & Medicinal Chemistry Letters
Volume:28
Issue:11
First Page:2008
Last Page:2012
ISSN:0960-894X
DOI:https://doi.org/10.1016/j.bmcl.2018.05.005
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=29748052
Publisher:Elsevier
Place of publication:Amsterdam
Date of first publication:2018/05/04
Tag:Cathepsins; Cysteine proteases; Horner-Wadsworth-Emmons olefination Irreversible inhibition; Michael acceptors
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Dewey Decimal Classification (DDC):5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Entry in this database:2018/05/09