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Synthesis and kinetic evaluation of ethyl acrylate and vinyl sulfone derived inhibitors for human cysteine cathepsins
Document Type: | Article |
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Language: | English |
Author: | Christian Breuer, Carina Lemke, Janina Schmitz, Ulrike Bartz, Michael Gütschow |
Parent Title (English): | Bioorganic & Medicinal Chemistry Letters |
Volume: | 28 |
Issue: | 11 |
First Page: | 2008 |
Last Page: | 2012 |
ISSN: | 0960-894X |
DOI: | https://doi.org/10.1016/j.bmcl.2018.05.005 |
PMID: | https://pubmed.ncbi.nlm.nih.gov/29748052 |
Publisher: | Elsevier |
Place of publication: | Amsterdam |
Date of first publication: | 2018/05/04 |
Keyword: | Cathepsins; Cysteine proteases; Horner-Wadsworth-Emmons olefination Irreversible inhibition; Michael acceptors |
Departments, institutes and facilities: | Fachbereich Angewandte Naturwissenschaften |
Dewey Decimal Classification (DDC): | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Entry in this database: | 2018/05/09 |