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N-Sulfonyl Dipeptide Nitriles as Inhibitors of Human Cathepsin S: In silico Design, Synthesis and Biochemical Characterization

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Metadaten
Document Type:Article
Language:English
Author:Carina Lemke, Lorenzo Cianni, Christian Feldmann, Erik Gilberg, Jiafei Yin, Fernanda dos Reis Rocho, Daniela de Vita, Ulrike Bartz, Jürgen Bajorath, Carlos A. Montanari, Michael Gütschow
Parent Title (English):Bioorganic & Medicinal Chemistry Letters
First Page:127420
ISSN:0960-894X
DOI:https://doi.org/10.1016/j.bmcl.2020.127420
Publisher:Elsevier
Date of first publication:2020/07/17
Submission status:In Press, Journal Pre-proof
Tag:cathepsin S; nitriles; reversible inhibition; sulfonamides
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Dewey Decimal Classification (DDC):5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 572 Biochemie
Entry in this database:2020/07/22