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An Activity-Based Probe for Cathepsin K Imaging with Excellent Potency and Selectivity

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Metadaten
Document Type:Article
Language:English
Author:Carina Lemke, Jakub Benýšek, Dominik Brajtenbach, Christian Breuer, Adéla Jílková, Martin Horn, Michal Buša, Lenka Ulrychová, Annika Illies, Katharina F. Kubatzky, Ulrike Bartz, Michael Mareš, Michael Gütschow
Parent Title (English):Journal of Medicinal Chemistry
Volume:64
Issue:18
First Page:13793
Last Page:13806
ISSN:0022-2623
DOI:https://doi.org/10.1021/acs.jmedchem.1c01178
PMID:https://pubmed.ncbi.nlm.nih.gov/34473502
Publisher:American Chemical Society (ACS)
Date of first publication:2021/09/02
Copyright:© 2021 American Chemical Society
Funding:C.L. thanks the Bonn International Graduate School of Drug Sciences (BIGS-DrugS)/BMBF for obtaining a grant (16GW0025). C.B. was supported by a grant from the Department of Natural Sciences, University of Applied Sciences Bonn-Rhein-Sieg. M.M., J.B., A.J., M.H., M.B., and L.U. were supported by the project ChemBioDrug CZ.02.1.01/0.0/0.0/16_019/0000729 from ERDF/OPRDE, Gilead Sciences & IOCB Research Center, and the institutional project RVO 61388963.
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Dewey Decimal Classification (DDC):5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Entry in this database:2021/09/06