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STAT3 gain-of-function mutations associated with autoimmune lymphoproliferative syndrome like disease deregulate lymphocyte apoptosis and can be targeted by BH3 mimetic compounds

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Metadaten
Document Type:Article
Language:English
Author:Schafiq Nabhani, Cyrill Schipp, Hagit Miskin, Carina Levin, Sergey Postovsky, Tal Dujovny, Ariel Koren, Dan Harlev, Anne-Marie Bis, Franziska Auer, Baerbel Keller, Klaus Warnatz, Michael Gombert, Sebastian Ginzel, Arndt Borkhardt, Polina Stepensky, Ute Fischer
Parent Title (English):Clinical Immunology
Volume:181
First Page:32
Last Page:42
ISSN:1521-6616
DOI:https://doi.org/10.1016/j.clim.2017.05.021
PMID:https://pubmed.ncbi.nlm.nih.gov/28579554
Publisher:Elsevier
Date of first publication:2017/06/27
Keyword:ABT-737; ALPS; BCL2; BH3-mimetic inhibitor; STAT3; apoptosis
Departments, institutes and facilities:Fachbereich Informatik
Dewey Decimal Classification (DDC):6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Entry in this database:2017/06/08