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N-Sulfonyl Dipeptide Nitriles as Inhibitors of Human Cathepsin S: In silico Design, Synthesis and Biochemical Characterization
Document Type: | Article |
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Language: | English |
Author: | Carina Lemke, Lorenzo Cianni, Christian Feldmann, Erik Gilberg, Jiafei Yin, Fernanda dos Reis Rocho, Daniela de Vita, Ulrike Bartz, Jürgen Bajorath, Carlos A. Montanari, Michael Gütschow |
Parent Title (English): | Bioorganic & Medicinal Chemistry Letters |
Volume: | 30 |
Issue: | 18 |
Article Number: | 127420 |
ISSN: | 0960-894X |
DOI: | https://doi.org/10.1016/j.bmcl.2020.127420 |
PMID: | https://pubmed.ncbi.nlm.nih.gov/32763808 |
Publisher: | Pergamon-Elsevier |
Place of publication: | Oxford |
Date of first publication: | 2020/07/17 |
Keyword: | Cathepsin S; Nitriles; Reversible inhibition; Sulfonamides |
Departments, institutes and facilities: | Fachbereich Angewandte Naturwissenschaften |
Dewey Decimal Classification (DDC): | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 572 Biochemie |
Entry in this database: | 2020/07/22 |