Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors
Document Type: | Article |
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Language: | English |
Author: | Janina Schmitz, Norbert Furtmann, Moritz Ponert, Maxim Frizler, Reik Löser, Ulrike Bartz, Jürgen Bajorath, Michael Gütschow |
Parent Title (English): | ChemMedChem |
Volume: | 10 |
Issue: | 8 |
First Page: | 1365 |
Last Page: | 1377 |
ISSN: | 1860-7179 |
DOI: | https://doi.org/10.1002/cmdc.201500151 |
PMID: | https://pubmed.ncbi.nlm.nih.gov/26119278 |
Publisher: | Wiley VCH |
Place of publication: | Weinheim |
Date of first publication: | 2015/06/26 |
Copyright: | © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim |
Funding: | J.S. is supported by the Gender Equality Center of the Bonn-Rhein-Sieg University of Applied Sciences, and N.F. by a fellowship from the Jurgen Manchot Foundation (Dusseldorf, Germany). |
Keyword: | 3D activity landscapes; cysteine proteases; human cathepsins; nitrile inhibitors |
Departments, institutes and facilities: | Fachbereich Angewandte Naturwissenschaften |
Dewey Decimal Classification (DDC): | 5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften |
Entry in this database: | 2015/08/21 |