The search result changed since you submitted your search request. Documents might be displayed in a different sort order.
  • search hit 1 of 5
Back to Result List

Lignin-Derived Biomaterials for Drug Release and Tissue Engineering

  • Renewable resources are gaining increasing interest as a source for environmentally benign biomaterials, such as drug encapsulation/release compounds, and scaffolds for tissue engineering in regenerative medicine. Being the second largest naturally abundant polymer, the interest in lignin valorization for biomedical utilization is rapidly growing. Depending on its resource and isolation procedure, lignin shows specific antioxidant and antimicrobial activity. Today, efforts in research and industry are directed toward lignin utilization as a renewable macromolecular building block for the preparation of polymeric drug encapsulation and scaffold materials. Within the last five years, remarkable progress has been made in isolation, functionalization and modification of lignin and lignin-derived compounds. However, the literature so far mainly focuses lignin-derived fuels, lubricants and resins. The purpose of this review is to summarize the current state of the art and to highlight the most important results in the field of lignin-based materials for potential use in biomedicine (reported in 2014⁻2018). Special focus is placed on lignin-derived nanomaterials for drug encapsulation and release as well as lignin hybrid materials used as scaffolds for guided bone regeneration in stem cell-based therapies.

Download full text files

Export metadata

Additional Services

Share in Twitter Search Google Scholar Availability
Metadaten
Document Type:Article
Language:English
Parent Title (English):Molecules
Volume:23
Issue:8
First Page:1885
ISSN:1420-3049
URN:urn:nbn:de:hbz:1044-opus-38578
DOI:https://doi.org/10.3390/molecules23081885
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=30060536
Publisher:MDPI
Place of publication:Basel
Date of first publication:2018/07/27
Note:
Funding: APC was sponsored by MDPI. Financial support via BMBF program "IngenieurNachwuchs" projects "LignoBau" (03FH013IX4) and "PersoImplant" (03FH019IX5); BRSU Graduate Institute for scholar ship (A.A., M.B., B.E.-H., D.H.) and Erasmus-Mundus Avempace-II scholar ship (A.A.).
Note:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Tag:biomaterial; bone regeneration; drug release; hydrogel; lignin; multivariate data processing; osteogenesis; scaffolds; stem cells; tissue engineering
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Dewey Decimal Classification (DDC):5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Entry in this database:2018/08/10
Licence (German):License LogoCreative Commons - CC BY - Namensnennung 4.0 International