Fasting Intact Proinsulin Is a Highly Specific Predictor of Insulin Resistance in Type 2 Diabetes
- OBJECTIVE—In later stages of type 2 diabetes, proinsulin and proinsulin-like molecules are secreted in increasing amounts with insulin. A recently introduced chemiluminescence assay is able to detect the uncleaved “intact” proinsulin and differentiate it from proinsulin-like molecules. This investigation explored the predictive value of intact proinsulin as an insulin resistance marker.
| Document Type: | Article |
|---|---|
| Language: | English |
| Author: | A. Pfutzner, T. Kunt, C. Hohberg, A. Mondok, S. Pahler, T. Konrad, G. Lubben, T. Forst |
| Parent Title (English): | Diabetes Care |
| Volume: | 27 |
| Issue: | 3 |
| First Page: | 682 |
| Last Page: | 687 |
| ISSN: | 0149-5992 |
| DOI: | https://doi.org/10.2337/diacare.27.3.682 |
| Publisher: | American Diabetes Association |
| Place of publication: | Alexandria, Va. |
| Date of first publication: | 2004/02/26 |
| Departments, institutes and facilities: | Fachbereich Angewandte Naturwissenschaften |
| Dewey Decimal Classification (DDC): | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Entry in this database: | 2018/06/08 |
