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Fasting Intact Proinsulin Is a Highly Specific Predictor of Insulin Resistance in Type 2 Diabetes

  • OBJECTIVE—In later stages of type 2 diabetes, proinsulin and proinsulin-like molecules are secreted in increasing amounts with insulin. A recently introduced chemiluminescence assay is able to detect the uncleaved “intact” proinsulin and differentiate it from proinsulin-like molecules. This investigation explored the predictive value of intact proinsulin as an insulin resistance marker.

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Document Type:Article
Author:A. Pfutzner, T. Kunt, C. Hohberg, A. Mondok, S. Pahler, T. Konrad, G. Lubben, T. Forst
Parent Title (English):Diabetes Care
First Page:682
Last Page:687
Publisher:American Diabetes Association
Place of publication:Alexandria, Va.
Date of first publication:2004/02/26
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Dewey Decimal Classification (DDC):6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Entry in this database:2018/06/08