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Acylpeptide hydrolase (APEH) sequence variants with potential impact on the metabolism of the antiepileptic drug valproic acid

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Document Type:Article
Author:Despina Tsortouktzidis, Kathleen Grundke, Claudia Till, Anne Korwitz-Reichelt, Jörn Oliver Sass
Parent Title (English):Metabolic Brain Disease
First Page:1629
Last Page:1634
Publisher:Springer US
Date of first publication:2019/07/30
Funding:This research was supported by 'Startforderung' of Bonn-Rhein-Sieg University of Applied Sciences and Anna Feddersen-Wagner-Fonds of University of Zurich, both to J.O.S. He also gratefully acknowledges financial support by the programs FH-Struktur ('FunForGen', 322-08-03-04-02) and FH Zeit fur Forschung ('KETOplus', 005-1703-0016) of the Ministry of Culture and Science of the German State of North Rhine-Westphalia.
Keyword:Acylpeptide hydrolase; Aminoacylase; Carbapenem; Pharmacogenetics; Polymorphism; Valproic acid
Departments, institutes and facilities:Fachbereich Angewandte Naturwissenschaften
Institut für funktionale Gen-Analytik (IFGA)
Projects:FunForGen - Funktionale und forensische Genomik mittels Next Generation Sequencing (DE/MKW NRW/322-08-03-04-02)
KETOplus - Ketonkörper: Mehr als nur Energieträger! (DE/MKW NRW/005-1703-0016)
Dewey Decimal Classification (DDC):5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Entry in this database:2019/08/06