Composite nanoparticles derived by self-assembling of hydrophobic polysaccharide derivatives and lignin
- Composite nanoparticles (NPs) consisting of lignin and different polysaccharide (PS) derivatives were prepared. In this synergistic approach, the PS derivative acts as biocompatible matrix that forms spherical NPs while lignin is a functional compound with therapeutic potential (e.g., antioxidative, antimicrobial, antiviral). Organosolv lignin and three different PS derivatives (cellulose acetate/CA, cellulose acetate phthalate/CAPh, xylan phenyl carbonate/XPC) were used in this study. Nanocomposites with particle sizes in the range of about 200–550 nm containing both types of biopolymers are accessible by dialysis of organic PS/lignin solutions against water. In particular, XPC and CAPh, which both contain aromatic substituents, were found to be suitable for incorporation of lignin within the PS nanomatrix. The present work paves the way for future studies in which the pharmaceutical potential and biocompatibility of composite NPs of lignin and PS derivatives with tailored properties are investigated.
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| Document Type: | Article |
|---|---|
| Language: | English |
| Author: | Martin Gericke, Jonas Bergrath, Margit Schulze, Thomas Heinze |
| Parent Title (English): | Cellulose |
| Volume: | 29 |
| Issue: | 7 |
| Number of pages: | 8 |
| First Page: | 3613 |
| Last Page: | 3620 |
| ISSN: | 0969-0239 |
| ISSN: | 1572-882X |
| URN: | urn:nbn:de:hbz:1044-opus-61447 |
| DOI: | https://doi.org/10.1007/s10570-022-04504-x |
| Publisher: | Springer |
| Publishing Institution: | Hochschule Bonn-Rhein-Sieg |
| Date of first publication: | 2022/03/26 |
| Copyright: | © The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International License. |
| Funding: | Open Access funding enabled and organized by Projekt DEAL. The authors have not disclosed any funding. |
| Keyword: | Biopolymers; Composites; Lignin; Nanoparticles; Polysaccharide derivatives; Self-assembling |
| Departments, institutes and facilities: | Fachbereich Angewandte Naturwissenschaften |
| Dewey Decimal Classification (DDC): | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| Entry in this database: | 2022/03/30 |
| Licence (German): |  Creative Commons - CC BY - Namensnennung 4.0 International |
