Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing
Document Type: | Article |
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Language: | English |
Author: | Oskar Schnappauf, Sven Beyes, Annika Dertmann, Vivien Freihen, Patrick Frey, Sabine Jägle, Katja Rose, Tom Michoel, Rudolf Grosschedl, Andreas Hecht |
Parent Title (English): | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms |
Volume: | 1859 |
Issue: | 11 |
Number of pages: | 15 |
First Page: | 1353 |
Last Page: | 1367 |
ISSN: | 0006-3002 |
DOI: | https://doi.org/10.1016/j.bbagrm.2016.08.002 |
PMID: | https://pubmed.ncbi.nlm.nih.gov/27504909 |
Publisher: | Elsevier |
Date of first publication: | 2016/08/05 |
Copyright: | © 2016 Elsevier B.V. All rights reserved. |
Keywords: | EPHB2; Epithelial-mesenchymal transition; FOXA1; LEF1; MYB; Transcriptional enhancer |
Departments, institutes and facilities: | Institut für funktionale Gen-Analytik (IFGA) |
Dewey Decimal Classification (DDC): | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
Entry in this database: | 2023/07/27 |