Inflammatory molecules are cell-to-cell transported by exosomes in the anti-inflammatory human autologous conditioned serum
- Background: Local injection of autologous conditioned serum (ACS) is a well-known therapy for inflammatory diseases (IDs). While patients’ blood is incubated to generate ACS (with subsequent centrifugation), immune cells produce high amounts of growth factors and cytokines. This include, amongst others, interleukin-1 receptor antagonist (IL-1ra), interleukins 6 and 10, tumour necrosis factor alpha (TNF-α) and transforming growth factor beta 1 (TGF-β1). The aim of this study was to analyse exosomes release into ACS as well as their cytokine cargo.
| Document Type: | Article |
|---|---|
| Language: | English |
| Author: | Maria Weisshaar, Jamal Ghanam, Stephan Irsen, Julio Reinecke, Peter Wehling |
| Parent Title (English): | Journal of Extracellular Vesicles |
| Volume: | 7 |
| Issue: | sup1 |
| First Page: | 142 |
| ISSN: | 2001-3078 |
| URL: | https://doi.org/10.1080/20013078.2018.1461450 |
| Publisher: | Taylor & Francis |
| Date of first publication: | 2018/05/04 |
| Note: | ISEV2018 abstract book |
| Departments, institutes and facilities: | Fachbereich Angewandte Naturwissenschaften |
| Dewey Decimal Classification (DDC): | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| Entry in this database: | 2018/05/04 |
