Refine
H-BRS Bibliography
- yes (2484) (remove)
Departments, institutes and facilities
- Fachbereich Informatik (975)
- Fachbereich Angewandte Naturwissenschaften (627)
- Institut für Technik, Ressourcenschonung und Energieeffizienz (TREE) (385)
- Fachbereich Ingenieurwissenschaften und Kommunikation (382)
- Fachbereich Wirtschaftswissenschaften (315)
- Institute of Visual Computing (IVC) (286)
- Institut für funktionale Gen-Analytik (IFGA) (231)
- Internationales Zentrum für Nachhaltige Entwicklung (IZNE) (126)
- Institut für Cyber Security & Privacy (ICSP) (105)
- Institut für Verbraucherinformatik (IVI) (103)
Document Type
- Article (1012)
- Conference Object (918)
- Part of a Book (187)
- Preprint (86)
- Doctoral Thesis (52)
- Report (51)
- Book (monograph, edited volume) (43)
- Master's Thesis (29)
- Working Paper (28)
- Research Data (22)
Year of publication
Language
- English (2484) (remove)
Keywords
- Virtual Reality (15)
- FPGA (14)
- Machine Learning (14)
- GC/MS (13)
- Robotics (13)
- Sustainability (11)
- virtual reality (11)
- Augmented Reality (9)
- Lignin (9)
- Social Protection (9)
In order to help journalists investigate inside large audiovisual archives, as maintained by news broadcast agencies, the multimedia data must be indexed by text-based search engies. By automatically creating a transcript through automatic speech recognition (ASR), the spoken word becomes accessible to text search, and queries for keywords are made possible. But stil, important contextual information like the identity of the speaker is not captured. Especially when gathering original footage in the political domain, the identity of the speaker can be the most important query constraint, although this name may not be prominent in the words spoken. It is thus desireable to have this information provided explicitely to the search engine. To provide this information, the archive must be an alyzed by automatic Speaker Identification (SID). While this research topic has seen substantial gains in accuracy and robustness over last years, it has not yet established itself as a helpful, large-scale tool outside the research community. This thesis sets out to establish a workflow to provide automatic speaker identification. Its application is to help journalists searching on speeches given in the German parliament (Bundestag). This is a contribution to the News-Stream 3.0 project, a BMBF funded research project that addresses accessibility of various data sources for journalists.
DNA Sequencing
(2011)
Interactive Distributed Rendering of 3D Scenes on Multiple Xbox 360 Systems and Personal Computers
(2012)
Transient up-regulation of P2 receptors influence differentiation of human mesenchymal stem cells
(2012)
Exposure to microgravity conditions causes cardiovascular deconditioning in astronauts during spaceflight. Until now, no specific drugs are available for countermeasure, since the underlying mechanism is largely unknown. Endothelial cells (ECs) and smooth muscle cells (SMCs) play key roles in various vascular functions, many of which are regulated by purinergic 2 (P2) receptors. However, their function in ECs and SMCs under microgravity conditions is still unclear. In this study, primary ECs and SMCs were isolated from bovine aorta and verified with specific markers. We show for the first time that the P2 receptor expression pattern is altered in ECs and SMCs after 24 h exposure to simulated microgravity using a clinostat. However, conditioned medium compensates this change in specific P2 receptors, for example, P2X7. Notably, P2 receptors such as P2X7 might be the important players during the paracrine interaction. Additionally, ECs and SMCs secreted different cytokines under simulated microgravity, leading into a pathogenic proliferation and migration. In conclusion, our data indicate P2 receptors might be important players responding to gravity changes in ECs and SMCs. Since some artificial P2 receptor ligands are applied as drugs, it is reasonable to assume that they might be promising candidates against cardiovascular deconditioning in the future.
Human mesenchymal stem cells (hMSCs) are considered a promising cell source for regenerative medicine, because they have the potential to differentiate into a variety of lineages among which the mesoderm-derived lineages such adipo- or osteogenesis are investigated best. Human MSCs can be harvested in reasonable to large amounts from several parts of the patient’s body and due to this possible autologous origin, allorecognition can be avoided. In addition, even in allogenic origin-derived donor cells, hMSCs generate a local immunosuppressive microenvironment, causing only a weak immune reaction. There is an increasing need for bone replacement in patients from all ages, due to a variety of reasons such as a new recreational behavior in young adults or age-related diseases. Adipogenic differentiation is another interesting lineage, because fat tissue is considered to be a major factor triggering atherosclerosis that ultimately leads to cardiovascular diseases, the main cause of death in industrialized countries. However, understanding the differentiation process in detail is obligatory to achieve a tight control of the process for future clinical applications to avoid undesired side effects. In this review, the current findings for adipo- and osteo-differentiation are summarized together with a brief statement on first clinical trials.