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We have designed an inexpensive intelligent pedestrian counting system. The pedestrian counting system consists of several counters that can be connected together in a distributed fashion and communicate over the wireless channel. The motion pattern is recorded using a set of passive infrared (PIR) sensors. Each counter has one wireless sensor node that processes the PIR sensor data and transmits it to a base station. Then echo state network, a special kind of recurrent neural network, is used to predict the pedestrian count from the input pattern. The evaluation of the performance of such networks in a novel kind of application is one focus of this work. The counter gave a performance of 80.4% which is better than the commercially available low-priced pedestrian counters. The article reports the experiments we did for analyzing the counterperformance and lists the strengths and limitations of the current implementation. It will also report the preliminary test results obtained by substituting the PIR sensors with low-cost active IR distance sensors which can improve the counter performance further.
In den vergangenen zehn Jahren haben sich die Suchmaschinen und insbesondere Google zu einem unverzichtbaren Bestandteil des Internets entwickelt. Parallel dazu hat die Anzahl von kommerziellen Websites zugenommen. Suchmaschinenmarketing bietet Unternehmen die Möglichkeit, Kunden nahezu ohne Streuverluste anzusprechen und somit Absatzziele optimal zu realisieren.
Background: Migration of mature and immature leukocytes in response to chemokines is not only essential during inflammation and host defense, but also during development of the hematopoietic system. Many molecules implicated in migratory polarity show uniform cellular distribution under non-activated conditions, but acquire a polarized localization upon exposure to migratory cues.
Methodology/Principal Findings: Here, we present evidence that raft-associated endocytic proteins (flotillins) are preassembled in lymphoid, myeloid and primitive hematopoietic cells and accumulate in the uropod during migration. Furthermore, flotillins display a polarized distribution during immunological synapse formation. Employing the membrane lipid-order sensitive probe Laurdan, we show that flotillin accumulation in the immunological synapse is concomittant with membrane ordering in these regions.
Conclusions: Together with the observation that flotillin polarization does not occur in other polarized cell types such as polarized epithelial cells, our results suggest a specific role for flotillins in hematopoietic cell polarization. Based on our results, we propose that in hematopoietic cells, flotillins provide intrinsic cues that govern segregation of certain microdomain-associated molecules during immune cell polarization.
Quereinsteiger und Neulinge der Vermittlung von Informationskompetenz werden grundlegend auf der Basis der vielfältigen praktischen Erfahrungen des Multiplikatorennetzwerks der AG Informationskompetenz NRW über strategische Konzepte, unterschiedliche Schulungsangebote für verschiedene Zielgruppen, Methodik und Didaktik von Schulungsveranstaltungen, Organisation und Infrastruktur sowie Evaluation und Qualitätsmanagement informiert.
Die traditionelle Managementtheorie fußt auf der Annahme, dass ein Unternehmen das Ergebnis bewusster, zweckrationaler Planung und Gestaltung ist und dass die Handlungen innerhalb der Strukturen eines Unternehmens ebenfalls zweckrational geleitet sind – oder dass sie dies zumindest sein sollten. Die meisten Modelle, die aus diesem traditionellen Grundverständnis hervorgegangen sind, folgen einer idealtypischen präskriptiven Grundlogik: Um ein Unternehmen erfolgreich in die Zukunft zu führen, beginnt man mit der Definition der unternehmerischen Ziele, analysiert das Unternehmen und seine Umwelt, entwirft und bewertet strategische Optionen, wählt eine dieser Optionen zur Umsetzung aus, strukturiert mit Hilfe von Maßnahmenplänen, Budgets und Zeitplänen den Umsetzungsprozess, kontrolliert den Fortschritt und die erzielten Ergebnisse und greift bei negativen Abweichungen vom angestrebten Soll gegebenenfalls korrigierend ein. Strategien sind in diesem Verständnis das explizit formulierbare Resultat eines aktiven, zielgerichteten, bewussten und rationalen Denkvorganges. Die Verantwortung für ihre Formulierung liegt in den Händen des Topmanagements. Es fällt die entsprechenden Entscheidungen und kontrolliert ihre Implementierung.
Publikation Umweltdaten
(2009)
In this article we introduce the concept and the first implementation of a lightweight client-server-framework as middleware for distributed computing. On the client side an installation without administrative rights or privileged ports can turn any computer into a worker node. Only a Java runtime environment and the JAR files comprising the workflow client are needed. To connect all clients to the engine one open server port is sufficient. The engine submits data to the clients and orchestrates their work by workflow descriptions from a central database. Clients request new task descriptions periodically, thus the system is robust against network failures. In the basic set-up, data up- and downloads are handled via HTTP communication with the server. The performance of the modular system could additionally be improved using dedicated file servers or distributed network file systems. We demonstrate the design features of the proposed engine in real-world applications from mechanical engineering. We have used this system on a compute cluster in design-of-experiment studies, parameter optimisations and robustness validations of finite element structures.
Asymmetric threats require powerful surveillance technology which helps to preserve the security. Security checks which focus on Improvised Explosive Devices (IED’s) or the identification of persons carrying hazardous substances are the major task of our research within the HAMLeT+ (Hazardous Material Localization and Person Tracking) project. Further on, there is a pressing need for assisting the security personnel, either civil or military, by extending the detection capabilities and to deliver efficient and reliable, real time decision support for their task to percept threats. Military camp protection with heterogeneous net-worked sensors and comprehensive sensor data fusion could be such an element. The technology developments concentrate on the integration of different sensor types (video, tracking sensors, CBRNE sensors) in order to get a better and comprehensive understanding in a defined entry area. Data fusion is used to combine kinematic data of persons (where, when) with additional attribute information of them (what) in order to identify that single person carrying the attributes and to classify the threat. The project was initiated as a Supporting Activity funded by the EU within the PASR 2006 scheme. With regards to the specific task for military camp protection it was extended and redesigned. In HAMLeT+ several chemical sensors for hydrocarbons like fuels, alcohols or solvents were used. Such chemicals are available in bigger amounts on the free market. Using them e.g. as fire accelerants they can cause a huge damage. Therefore their detection or the detection of persons carrying such substances or having contaminations on their clothes is of great interest. Sensitive devices for the detection of these analytes are e.g. metal oxide sensors [1]. Our presentation illustrates experimental data, which were gathered with the experimental system HAMLeT+ during the NATO “Defense Against Terrorism (DAT)” campaign „COMMON SHIELDS” in August and September 2008.
We introduce our Lessons Learned from the NATO CNAD PoW “Defense Against Terrorism (DAT)” campaign „COMMON SHIELD” from August and September 2008, present our data and illustrate our experience, which were gathered with the experimental system HAMLeT+ (Hazardous Material Localization and Person Tracking Plus) for military camp protection. The focus of „COMMON SHIELD” was the network-centric operation and demon-stration of innovative technologies for Intelligence, Surveillance, Reconnaissance and Target Acquisition of Terrorists (ISRTA). With regard to the specific task for military camp protection, the original demonstrator HAMLeT [1], which was initiated as a Supporting Activity funded by the EU within the PASR 2006 scheme, was extended and redesigned as HAMLeT+. In HAMLeT+ several chemical sensors for hydrocarbons like fuels, alcohols or solvents were used. The identification of persons carrying hazardous substances and the classification of those substances are the major task of our research. Further on, there is a pressing need for assistance systems for the guards, to extend the spectra of detection capabilities and to receive efficient and reliable, real time decision support for the task to percept threats, which so far could not even be realized at an entry control facility. Security assistance by means of heterogeneous net-worked sensors and comprehensive sensor data fusion could be such an element for better protection. New technological developments concentrate on the integration of different sensor types (video, tracking sensors, CRE sensors) in order to get a better and comprehensive understanding of potential threats in a defined area. Multiple sensors data fusion can be used to combine complementary types of data e.g. kinematic data of objects (where, when) with additional attribute information (what) in order to identify those objects carrying the attributes of interest and give a classification of the potential threat.
Microwave Kinetic Inductance Detectors have great potential for large very sensitive detector arrays for use in, for example, ground and spaced based sub?mm imaging. Being intrinsically readout in the frequency domain, they are particularly suited for frequency domain multiplexing allowing 1000s of devices to be readout with one pair of coaxial cables. However, this moves the complexity of the detector from the cryogenics to the warm electronics. We present the use of a readout based on a Fast Fourier transform Spectrometer, showing no deterioration of the noise performance compared to low noise analog mixing while allowing high multiplexing ratios (>100). We present use of this technique to multiplex 44 MKIDs, while this and similar setups are regularly now being used in our array development. This development will help the realization of large cameras, particularly in the short term for ground based astronomy.
We review the development of our digital broadband Fast Fourier Transform Spectrometers (FFTS). In just a few years, FFTS back-ends - optimized for a wide range of radio astronomical applications - have become a new standard for heterodyne receivers, particularly in the mm and sub-mm wavelength range. They offer high instantaneous bandwidths with many thousands spectral channels on a small electronic board (100 x 160 mm). Our FFT spectrometer make use of the latest versions of GHz analog-to-digital converters (ADC) and the most complex field programmable gate array (FPGA) chips commercially available today. These state-of-the-art chips have made possible to build digital spectrometers with instantaneous bandwidths up to 1.8 GHz and 8192 spectral channels.
GREAT, the German REceiver for Astronomy at THz frequencies, has successfully passed its pre-shipment acceptance review conducted by DLR and NASA on December 4-5, 2008. Shipment to DAOF/Palmdale, home of the SOFIA observatory, has been released; airworthiness was stated by NASA. Since, due to schedule slips on the SOFIA project level, first science flights with GREAT were delayed to mid 2010. Here we present GREAT’s short science flight configuration: two heterodyne channels will be operated simultaneously in the frequency ranges of 1.25-1.50 and 1.82-1.91 THz, respectively, driven by solid-state type local oscillator systems, and supported by a wide suite of back-ends. The receiver was extensively tested for about 6 month in the MPIfR labs, showing performances compliant with specifications. This short science configuration will be available to the interested SOFIA user communities in collaboration with the GREAT PI team during SOFIA’s upcoming Basic Science flights.
Kinetic Inductance Detectors with Integrated Antennas for Ground and Space-Based Sub-mm Astronomy
(2009)
Very large arrays of Microwave Kinetic Inductance Detectors (MKIDs) have the potential to revolutionize ground and space based astronomy. They can offer in excess of 10.000 pixels with large dynamic range and very high sensitivity in combination with very efficient frequency division multiplexing at GHz frequencies. In this paper we present the development of a 400 pixel MKID demonstration array, including optical coupling, sensitivity measurements, beam pattern measurements and readout. The design presented can be scaled to any frequency between 80 GHz and >5 THz because there is no need for superconducting structures that become lossy at frequencies above the gap frequency of the materials used. The latter would limit the frequency coverage to below 1 THz for relatively high gap materials such as NbTiN. An individual pixels of the array consist of a distributed Aluminium CPW MKID with an integrated twin slot antenna at its end. The antenna is placed in the in the second focus of an elliptical high purity Si lens. The lens-antenna coupling design allows room for the MKID resonator outside of the focal point of the lens. The best dark noise equivalent power of these devices is measured to be NEP = 7×10-19 W/[square root]Hz and the optical coupling efficiency is around 30%, in which no antireflection coating was used on the Si lens. For the readout we use a commercial arbitrary waveform generator and a 1.5 GHz FFTS. We show that using this concept it is possible to read out in excess of 400 pixels with 1 board and 1 pair of coaxial cables.
Background: Bile acids, end products of the pathway for cholesterol elimination, are required for dietary lipid and fatsoluble vitamin absorption and maintain the balance between cholesterol synthesis in the liver and cholesterol excretion. They are composed of a steroid structure and are primarily made in the liver by the oxidation of cholesterol. Cholesterol is also highly abundant in the human ovarian follicle, where it is used in the formation of the sex steroids.
Methodology/Principal Findings: Here we describe for the first time evidence that all aspects of the bile acid synthesis pathway are present in the human ovarian follicle, including the enzymes in both the classical and alternative pathways, the nuclear receptors known to regulate the pathway, and the end product bile acids. Furthermore, we provide functional evidence that bile acids are produced by the human follicular granulosa cells in response to cholesterol presence in the culture media.
Conclusions/Significance: These findings establish a novel pathway present in the human ovarian follicle that has the capacity to compete directly with sex steroid synthesis.
This paper presents an approach to estimate theego-motion of a robot while moving. The employed sensor is aTime-of-Flight (ToF) camera, the SR3000 from Mesa Imaging.ToF cameras provide depth and reflectance data of the scene athigh frame rates.The proposed method utilizes the coherence of depth andreflectance data of ToF cameras by detecting image features onreflectance data and estimating the motion on depth data. Themotion estimate of the camera is fused with inertial measure-ments to gain higher accuracy and robustness.The result of the algorithm is benchmarked against referenceposes determined by matching accurate 2D range scans. Theevaluation shows that fusing the pose estimate with the datafromthe IMU improves the accuracy and robustness of the motionestimate against distorted measurements from the sensor.
In den Medien wird momentan immer mehr die Rolle von klein- und mittelständischen Betrieben, als "Jobmotor" für Deutschland betont. Darunter fallen auch Neugründungen. Wirtschaftspolitisch interessant sind deswegen vor allem innovative, wachstumsstarke Existenzgründungen. Verschiedene Untersuchungen geben Grund zu der Annahme, dass vornehmlich Hochschulabsolventen solche Unternehmen gründen. "Unternehmerisches Denken" ist eine Schlüsselqualifikation geworden, die für die berufliche Zukunft von Hochschulabsolventen von steigender Bedeutung ist. Unternehmern zugesprochene Eigenschaften, wie Eigeninitiative, Übernahme von Verantwortung, Führungsqualität und Belastbarkeit auch in besonderen Stresssituationen sind für viele etablierte Unternehmen als Einstellungskriterium für Akademiker stärker in den Vordergrund gerückt.
Während sich die Zahl entschädigungspflichtiger Arbeitsunfälle im Zeitraum der letzten 10 Jahre kontinuierlich zurückentwickelt hat, nehmen Prävalenz und Inzidenz der psychischen Erkrankungen und Verhaltensstörungen nach Kapitel F der ICD-10 stetig zu. Nach einer Prognose der "Burden of Disease Study" von WHO und Weltbank werden Depressionen im Jahr 2020 weltweit den zweiten Rang unter den Behinderung verursachenden Erkrankungen eingenommen haben. Manche Autoren betrachten schon heute die Erkrankungen nach Kapitel F der ICD-10 als "Die Epidemie des 21. Jahrhunderts". Neben den krankheitsbedingten Arbeitsausfällen aufgrund psychischer Gesundheitsstörungen ergeben sich auch ökonomische Belastungen infolge notwendig werdender Therapien und ein Verlust von Erfahrungswissen infolge verfrühten Eintritts ins Rentenalter seitens der Erkrankten. Als mögliche Einflussfaktoren auf die zunehmenden psychischen Erkrankungen werden neben individueller Veranlagung auch Stressoren aus der Gesellschaft postuliert, zu nennen wären hier beispielhaft die kontinuierliche Angst um den Arbeitsplatz oder Distress im Beruf aufgrund dauernder Überlastung.
Es gehört nicht zum Alltag von Hochschullehrern, das Entstehen einer neuen Wissenschaft zu betrachten und zu beschreiben, geschweige denn an diesem Prozess beteiligt zu sein. Der Fachbereich Sozialversicherung der Fachhochschule Bonn-Rhein-Sieg hat sich dieses Vergnügen im Jahre 2007 gegönnt und dazu angesetzt, eine neue Wissenschaft "aus der Taufe zu heben" – die Sozialversicherungswissenschaft.
Embryonic stem cells (ES) have the potential of long-term viability, selfrenewal and pluripotency which makes them interesting candidates for tissue engineering and gene therapy applications. On the other hand ethical and political issues arise while using theses cells and severe problems such as their tumorgenicity have not been solved yet. In the last couple of month a new source of cells with stem cell character was developed, the induced pluripotent stem cells (iPS). These cells are derived from differentiated adult cells via transduction of three transcription factors and show features similar to embryonic stem cells. Unfortunately, this includes the tumorgenicity which is even higher in those cells since the transcription factor transduction needed until now, is performed with retrovial vectors, which have a tumor potential on their own. Thus, adult stem cells are investigated extensively as alternative source of self-renewing cells. Human mesenchymal stem cells (HMSCs), which have in addition the advantage of potential autologous transplantation, can be found in various differentiated tissues since they are needed for maintenance and repair. They can be differentiated in chondrogenic, osteogenic, adipogenic and myogenic lineages which makes them an excellent tool for future tissue replacement strategies.
The ongoing miniaturization, multi-layer structure parts and hybrid parts require methods to determine mechanical properties on a micro-scale. However, there is a gap in measuring techniques. On one hand there are the classical methods to measure hardness e.g. VICKERS, ROCKWELL, UNIVERSAL, IRHD etc having resolutions typically above 100μm. On the other hand there are well-developed AFM methods that allow for the determination of mechanical properties in the nanometer range. This paper describes an indentation technique that yields data of mechanical properties in the micrometer range between typically 5 to 50 μm. The measuring device and the data evaluation is presented. Results of micro-mechanical mapping are shown for NR-SBR rubber interfaces, a fuel tank and a part manufactured by two component injection moulding. Finally, the measured micro-mechanical stiffness is compared to the YOUNG’s modulus of the corresponding materials.
A method for the identification of polymeric residues in recycled aluminium by using analytical pyrolysis at 700°C hyphenated to gas chromatography-mass spectrometry (Py-GC/MS) was presented for the first time. The polymeric residues in recycled aluminium were identified as a mixture of polyethylene, polystyrene, and phenolic resin. The described method could be useful for the aluminium industry as a part of the quality control of the recycled aluminium production.
Die Wiederverwertung von Kunststoffen (Kunststoffrecycling) kann in die werkstoffliche (materielle), die rohstoffliche (chemische) und die energetische Verwertung unterteilt werden. Beim werkstofflichen Kunststoffrecycling werden sortenreine Kunststoffreste gewaschen, gemahlen und von der Kunststoff verarbeitenden Industrie als Rohmaterial eingesetzt. Der chemische Aufbau des erhaltenen Werkstoffs (Re-Granulats) bleibt erhalten. Bei der rohstofflichen Verwertung werden Kunststoffreste zu Monomeren zurückgeführt. Die erhaltenen Monomere werden dann bei der Herstellung neuer Kunststoffe verwendet. Bei der energetischen Verwertung werden die Kunststoffreste der Zement- oder Stahlindustrie als Energieträger zugeführt.
Timely recognition of threats can be significantly supported by security assistance systems that work continuously in time and call the security personnel in case of anomalous events in the surveillance area. We describe the concept and the realization of an indoor security assistance system for real-time decision support. The system consists of a computer vision module and a person classification module. The computer vision module provides a video event analysis of the entrance region in front of the demonstrator. After entering the control corridor, the persons are tracked, classified, and potential threats are localized inside the demonstrator. Data for the person classification are provided by chemical sensors detecting hazardous materials. Due to their limited spatio-temporal resolution, a single chemical sensor cannot localize this material and associate it with a person. We compensate this deficiency by fusing the output of multiple, distributed chemical sensors with kinematical data from laser-range scanners. Considering both the computer vision formation and the results of the person classification affords the localization of threats and a timely reaction of the security personnel.
Der zunehmende Einsatz der Polymerwerkstoffe in der Automobilindustrie erfordert empfindliche und zuverlässige Methoden zur Analyse der verwendeten Stoffe. Bei Schadenanalysen an Komponenten in Kraftfahrzeugen stehen oftmals nur wenige Informationen über das Bauteil selbst, wie die chemische Zusammensetzung, die Temperaturbeständigkeit, mögliche Kontaminierungs stoffe oder mechanische Eigenschaften zur Verfügung. Der Schadensbereich ist meistens be grenzt und nicht immer homogen. Zur Klärung des Schadens stehen häufig nur kleine Proben mengen zur Verfügung, die jedoch für die Erkennung der Schadensursache von großer Bedeutung sein können.
Die analytische Pyrolyse ist eine universell einsetzbare Messtechnik zur Untersuchung von hoch molekularen organischen Verbindungen. Bei der Pyrolyse der hochmolekularen organischen Ver bindungen entstehen durch thermische Zersetzung bei 500-1400°C in einem Inertgasstrom nieder molekulare Verbindungen. Diese niedermolekularen Pyrolyse-Produkte werden dann den her kömmlichen Analyseverfahren wie GC-FID, GC/MS oder GC/FTIR unterworfen, die Rück schlüsse auf chemische Zusammensetzung und Struktur der Ausgangsstoffe erlauben. Die Festphasen mikroextraktion (SPME) ist eine lösungsmittelfreie Mikroextraktionstechnik. Im Headspace-Modus (HS) wurde SPME in den letzten Jahren für die Bestimmung von Rest mono meren und gesund heits gefährdenden, leichtflüchtigen organischen Verbindungen (VOCs) in Kunststoffen verwendet.
Refers To: Peter Kusch, Gerd Knupp, Marcus Hergarten, Marian Kozupa, Maria Majchrzak: Solid-phase extraction-gas chromatography and solid-phase extraction-gas chromatography–mass spectrometry determination of corrosion inhibiting long-chain primary alkyl amines in chemical treatment of boiler water in water-steam systems of power plants. - Journal of Chromatography A, Volume 1113, Issues 1–2, 28 April 2006, Pages 198-205
Gas chromatography with flame-ionization detection (FID) and gas chromatography-mass spectrometry (GC/MS) has been used for structure elucidation of long-chain primary n-alkyl amines after derivatization with trifluoroacetic anhydride (TFAA). Electron impact ionization- (EI) and positive chemical ionization- (PCI) mass spectra of trifluoroacetylated derivatives of the identified nalkyl amines are presented. The corrosion inhibiting n-alkyl amines were applied in the investigation of a new anticorrosive and antifouling formulation for water-steam circuit of energy systems in the power industry. The presented results are part of an EU-funded international collaboration with partners from research institutes and industry from Poland, Lithuania, Romania, France and Germany (EUREKA project BOILTREAT E!2426).