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- 2014 (236) (remove)
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Exposure to microgravity conditions causes cardiovascular deconditioning in astronauts during spaceflight. Until now, no specific drugs are available for countermeasure, since the underlying mechanism is largely unknown. Endothelial cells (ECs) and smooth muscle cells (SMCs) play key roles in various vascular functions, many of which are regulated by purinergic 2 (P2) receptors. However, their function in ECs and SMCs under microgravity conditions is still unclear. In this study, primary ECs and SMCs were isolated from bovine aorta and verified with specific markers. We show for the first time that the P2 receptor expression pattern is altered in ECs and SMCs after 24 h exposure to simulated microgravity using a clinostat. However, conditioned medium compensates this change in specific P2 receptors, for example, P2X7. Notably, P2 receptors such as P2X7 might be the important players during the paracrine interaction. Additionally, ECs and SMCs secreted different cytokines under simulated microgravity, leading into a pathogenic proliferation and migration. In conclusion, our data indicate P2 receptors might be important players responding to gravity changes in ECs and SMCs. Since some artificial P2 receptor ligands are applied as drugs, it is reasonable to assume that they might be promising candidates against cardiovascular deconditioning in the future.
The analytical pyrolysis technique hyphenated to gas chromatography–mass spectrometry (GC–MS) has extended the range of possible tools for the characterization of synthetic polymers and copolymers. Pyrolysis involves thermal fragmentation of the analytical sample at temperatures of 500–1400 °C. In the presence of an inert gas, reproducible decomposition products characteristic for the original polymer or copolymer sample are formed. The pyrolysis products are chromatographically separated using a fused-silica capillary column and are subsequently identified by interpretation of the obtained mass spectra or by using mass spectra libraries. The analytical technique eliminates the need for pretreatment by performing analyses directly on the solid or liquid polymer sample. In this article, application examples of analytical pyrolysis hyphenated to GC–MS for the identification of different polymeric materials in the plastic and automotive industry, dentistry, and occupational safety are demonstrated. For the first time, results of identification of commercial light-curing dental filling material and a car wrapping foil by pyrolysis–GC–MS are presented.
It has become increasingly clear that caspases, far from being merely cell death effectors, have a much wider range of functions within the cell. These functions are as diverse as signal transduction and cytoskeletal remodeling, and caspases are now known to have an essential role in cell proliferation, migration, and differentiation. There is also evidence that apoptotic cells themselves can direct the behavior of nearby cells through the caspase-dependent secretion of paracrine signaling factors. In some processes, including the differentiation of skeletal muscle myoblasts, both caspase activation in differentiating cells as well as signaling from apoptotic cells has been reported. Here, we review the non-apoptotic outcomes of caspase activity in a range of different model systems and attempt to integrate this knowledge.
Chemie kann im Studium ganz schön kompliziert sein, besonders wenn es etwas mehr in die Tiefe geht. Dass man aber auch komplizierte Dinge leicht verständlich und bisweilen amüsant erklären kann, beweist dieses Lehrbuch. Stefanie Ortanderl und Ulf Ritgen erklären die Grundlagen der Chemie und so erfahren Sie, was Sie über Atommodelle, Bindungstypen und das Periodensystem wissen sollten.
During space missions astronauts suffer from cardiovascular deconditioning, when they are exposed to microgravity conditions. Until now, no specific drugs are available for effective countermeasures, since the underlying mechanism is not completely understood. Endothelial cells (ECs) and smooth muscle cells (SMCs) play crucial roles in a variety of cardiovascular functions, many of which are regulated via P2 receptors. However, their function in ECs and SMCs under microgravity condition is still unknown. In this study, ECs and SMCs were isolated from bovine aorta and differentiated from human mesenchymal stem cells (hMSCs), respectively. Subsequently, the cells were verified based on specific markers. An altered P2 receptor expression pattern was detected during the commitment of hMSC towards ECs and SMCs. The administration of natural and artificial P2 receptor agonists and antagonists directly affected the differentiation process. By using EC growth medium as conditioned medium, a vessel cell model was created to culture SMCs and vice versa. Within this study, we were able to show for the first time that the expression of some P2 receptors were altered in ECs and SMCs grown for 24h under simulated microgravity conditions. On the other hand, in some P2 receptor expressions such as P2X7 conditioned medium compensated this change.
In conclusion, our data show that P2 receptors play an important functional role in hMSC differentiation towards ECs and SMCs. Since some P2 receptor artificial ligands are already used as drugs for patients with cardiovascular diseases, it is reasonable to assume that in the future they might be promising candidates for treating cardiovascular deconditioning.
Nitrile-type inhibitors are known to interact with cysteine proteases in a covalent-reversible manner. The chemotype of 3-cyano-3-aza-β-amino acid derivatives was designed in which the N-cyano group is centrally arranged in the molecule to allow for interactions with the nonprimed and primed binding regions of the target enzymes. These compounds were evaluated as inhibitors of the human cysteine cathepsins K, S, B, and L. They exhibited slow-binding behavior and were found to be exceptionally potent, in particular toward cathepsin K, with second-order rate constants up to 52 900 × 103 M–1 s–1.
Kriminalistik
(2014)
Der Beitrag beschreibt die Einführung eines prozessorientierten Qualitätsmanagementsystems (QM-System) an der Hochschule Bonn-Rhein-Sieg. Diese wurde 1995 gegründet und hat derzeit rund 6500 Studierende an drei Standorten: Sankt Augustin, Rheinbach und Hennef. Hier lehren und forschen rund 140 engagierte Professorinnen und Professoren, unterstützt durch über 300 Mitarbeiterinnen und Mitarbeiter und ebenso viele Lehrbeauftragte aus Wirtschaft, Politik und Wissenschaft. Angesichts der Verteilung über mehrere Standorte mit unterschiedlichen fachlichen Schwerpunkt- und Zielsetzungen wird der Aufbau eines gemeinsamen QM zugleich als Organisationsentwicklungsprozess gestaltet. Strategische Basis dafür ist der Hochschulentwicklungsplan. Begonnen wurde Ende 2009 mit der Erstellung einer Feasibility-Studie, um die zukünftige Rolle von QM an der Hochschule zu untersuchen und einen gangbaren Weg für die Integration in die Hochschulentwicklung zu beschreiben. Der folgende Bericht gibt einen Überblick über die daraus entstandenen Aktivitäten sowie einen Eindruck von den damit verbundenen Chancen und Schwierigkeiten. Einer der größten Erfolge besteht bislang in der Anerkennung von QM als Daueraufgabe der Hochschule und ihrer Mitglieder. Herausfordernd ist, diesen Anspruch im Hochschulalltag umzusetzen.
Sustainability is a key issue in current research activities and programs. In this conjunction three major functions of research have been identified: Basic research, knowledge reservoirs, and knowledge transfer. With regard to a transmission to the private sector, knowledge transfer is the most important factor. In this process, universities of applied sciences can play an important part as they typically have a long-standing experience in linking science and business in their teaching and research. Another important agent in the process of knowledge transfer are networks and clusters. Their strength lies integrating the different competencies of its partners and using them to a mutual benefit.
The International Centre for Sustainable Development (IZNE) – with a major focus on responsible business and sustainable food – takes the advantage of being part of a University of Applied Sciences (Bonn-Rhein-Sieg, BRSU), and being a member of several regional and international clusters and networks. These co-operations aim to establish and strengthen linkages between science and business, in particular by investigating research needs for business and business relevant research activities. Moreover, IZNE established and expanded regional and international co-operations of its own to get more transparency about regional and international value-added chains in the food sector and the issue of responsible business.
It is a euphemism to say that humans use tools. Humans possess a vast repertoire of tools they use every day. In fact, as language or bipedal locomotion, tool use is a hallmark of humans. Tool use has also been often viewed as an important step during evolution (van Schaik et al., 1999) or even as a marker of the evolution of human intelligence (Wynn, 1985). So a fundamental issue is, what are the cognitive and neural bases of human tool use? The present series of papers in this special topic represents the newest additions to that research topic.
Low power dissipation is a current topic in digital design, and therefore, it should be covered in a state-of-the-art electrical engineering curriculum. This paper describes how low-power design can be addressed within a digital design course. Doing so would be beneficial for both topics because low-power design is not detached from the systems perspective, and the digital design course would be enriched by references to current challenges and applications. Thus, the presented course should serve as an example of how a course can be developed to also teach students about sustainable engineering.
Automated parameterization of intermolecular pair potentials using global optimization techniques
(2014)
In this work, different global optimization techniques are assessed for the automated development of molecular force fields, as used in molecular dynamics and Monte Carlo simulations. The quest of finding suitable force field parameters is treated as a mathematical minimization problem. Intricate problem characteristics such as extremely costly and even abortive simulations, noisy simulation results, and especially multiple local minima naturally lead to the use of sophisticated global optimization algorithms. Five diverse algorithms (pure random search, recursive random search, CMA-ES, differential evolution, and taboo search) are compared to our own tailor-made solution named CoSMoS. CoSMoS is an automated workflow. It models the parameters’ influence on the simulation observables to detect a globally optimal set of parameters. It is shown how and why this approach is superior to other algorithms. Applied to suitable test functions and simulations for phosgene, CoSMoS effectively reduces the number of required simulations and real time for the optimization task.
An Universitäten und Fachhochschulen ist die Mathematik-Ausbildung eines der Nadelöhre für angehende Ingenieurinnen und Ingenieure. Viele Studierende der Ingenieurwissenschaften scheitern in den ersten Studiensemestern an den Anforderungen der Mathematik. Lehrende, Fach- und Hochschuldidaktiker/innen und zunehmend auch Fachvertretungen und Verbände stellen sich die Frage, was an den Fakultäten und Fachbereichen getan werden kann, damit Studierende ihre mathematischen Fähigkeiten vergrößern und den anspruchsvollen Studienweg zur Ingenieurin oder zum Ingenieur meistern können.
Corporate Design Leitfaden
(2014)
Seit vielen Jahren ist der Übergang von der Schule zur Hochschule eines der zentralen Themen für didaktische Theorien, empirische Untersuchungen und bildungspolitische Diskussionen. Ein dabei identifiziertes großes Problem vieler Studierender ist, dass mit dem Abitur „eine Lebensphase mit meist klar definierten Zielen in überschaubaren räumlichen, familiären und schulischen Strukturen endet“.1) Entscheidet man sich als Studierender gegen die nicht akademische Laufbahn und nimmt ein Hochschulstudium auf, trifft man auf Studienstrukturen und -bedingungen, die einem fremd und chaotisch vorkommen können. Der Weg an die Hochschulen ermöglicht den Individuen eine Reihe von Optionen, ist aber leider auch immer mit Risiken und Unsicherheiten behaftet. Entscheidungen müssen nun selbstständig vorbereitet und getroffen werden und dies in einem Umfeld, das sehr unterschiedlich im Vergleich zur bekannten Schulstruktur sein kann.
The Project SupraMetall: Towards Commercial Fabrication of High-Temperature Superconducting Tapes
(2014)
Automatisierungstechnik
(2014)
Die Automatisierungstechnik wird aus praktischer Sicht mit vielen Beispielen und zahlreichen Bildern veranschaulicht. Studenten ingenieurwissenschaftlicher Fachrichtungen sowie Ingenieure und Techniker in der Ausbildung und der beruflichen Praxis können sich auf dem Stand der Technik selbständig einarbeiten.
Informatikerinnen und Informatiker aller Fachrichtungen müssen die grundlegenden Konzepte, Methoden und Verfahren, die der Entwicklung und dem Einsatz von Informations- und Kommunikationstechnologien zugrunde liegen, verstehen und bei der Lösung von Problemen anwenden können. Das Buch stellt die algebraischen und zahlentheoretischen Grundlagen dafür vor und wendet diese bei der Lösung praktischer Problemstellungen, wie modulare Arithmetik, Primzahltests und Verschlüsselung an. Das Verständnis der Begriffe und deren Zusammenhänge und Zusammenwirken wird u.a. durch Lernziele, integrierte Übungsaufgaben mit Musterlösungen und Marginalien unterstützt. Das Buch ist zum Selbststudium gut geeignet.
In the field of domestic service robots, recovery from faults is crucial to promote user acceptance. In this context we focus in particular on some specific faults, which arise from the interaction of a robot with its real world environment. Even a well-modelled robot may fail to perform its tasks successfully due to unexpected situations, which occur while interacting. These situations occur as deviations of properties of the objects (manipulated by the robot) from their expected values. Hence, they are experienced by the robot as external faults.
Unexpected Situations in Service Robot Environment: Classification and Reasoning Using Naive Physics
(2014)
Current computer architectures are multi-threaded and make use of multiple CPU cores. Most garbage collections policies for the Java Virtual Machine include a stop-the-world phase, which means that all threads are suspended. A considerable portion of the execution time of Java programs is spent in these stop-the-world garbage collections. To improve this behavior, a thread-local allocation and garbage collection that only affects single threads, has been proposed. Unfortunately, only objects that are not accessible by other threads ("do not escape") are eligible for this kind of allocation. It is therefore necessary to reliably predict the escaping of objects. The work presented in this paper analyzes the escaping of objects based on the line of code (program counter – PC) the object was allocated at. The results show that on average 60-80% of the objects do not escape and can therefore be locally allocated.
Improving data acquisition techniques and rising computational power keep producing more and larger data sets that need to be analyzed. These data sets usually do not fit into a GPU's memory. To interactively visualize such data with direct volume rendering, sophisticated techniques for problem domain decomposition, memory management and rendering have to be used. The volume renderer Volt is used to show how CUDA is efficiently utilised to manage the volume data and a GPU's memory with the aim of low opacity volume renderings of large volumes at interactive frame rates.
Vielfalt ist unser Angebot
(2014)
Der Fachbereich Sozialversicherung der Hochschule Bonn-Rhein-Sieg blickt auf zehn erfolgreiche Jahre zurück. Seit Gründung des Fachbereichs im Jahr 2003 arbeiten Wissenschaftlerinnen und Wissenschaftler verschiedener Disziplinen auf dem Campus Hennef eng vernetzt im Untersuchungsfeld der Sozialversicherung.
In contrast to projection-based systems, large, high resolution multi-display systems offer a high pixel density on a large visualization area. This enables users to step up to the displays and see a small but highly detailed area. If the users move back a few steps they don't perceive details at pixel level but will instead get an overview of the whole visualization. Rendering techniques for design evaluation and review or for visualizing large volume data (e.g. Big Data applications) often use computationally expensive ray-based methods. Due to the number of pixels and the amount of data, these methods often do not achieve interactive frame rates.
A view direction based (VDB) rendering technique renders the user's central field of view in high quality whereas the surrounding is rendered with a level-of-detail approach depending on the distance to the user's central field of view. This approach mimics the physiology of the human eye and conserves the advantage of highly detailed information when standing close to the multi-display system as well as the general overview of the whole scene. In this paper we propose a prototype implementation and evaluation of a focus-based rendering technique based on a hybrid ray tracing/sparse voxel octree rendering approach.
Dies ist der Tagungsband zum elften aus einer Reihe erfolgreicher Workshops zum Thema Virtuelle und Erweiterte Realität, die von der Fachgruppe VR/AR der Gesellschaft für Informatik e.V. ins Leben gerufen wurde. Als etablierte Plattform für den Informations- und Ideenaustausch der deutschsprachigen VR/AR-Szene bietet der Workshop den idealen Rahmen, aktuelle Ergebnisse und Vorhaben aus Forschung und Entwicklung im Kreise eines fachkundigen Publikums zur Diskussion zu stellen. Insbesondere wollen wir auch jungen Nachwuchswissenschaftlern die Möglichkeit geben, ihre Arbeiten zu präsentieren.
This article describes an approach to rapidly prototype the parameters of a Java application run on the IBM J9 Virtual Machine in order to improve its performance. It works by analyzing VM output and searching for behavioral patterns. These patterns are matched against a list of known patterns for which rules exist that specify how to adapt the VM to a given application. Adapting the application is done by adding parameters and changing existing ones. The process is fully automated and carried out by a toolkit. The toolkit iteratively cycles through multiple possible parameter sets, benchmarks them and proposes the best alternative to the user. The user can, without any prior knowledge about the Java application or the VM improve the performance of the deployed application and quickly cycle through a multitude of different settings to benchmark them. When tested with the representative benchmarks, improvements of up to 150% were achieved.
A cost-efficient alternative to outside-in tracking systems for pointing interaction with large displays is to equip the pointing device with a camera, whose images are matched to display content. This work presents the Dynamic Marker Camera Tracking (DMCT) framework for display-based camera tracking. It accounts for typical display characteristics and uses dynamic on-screen markers overlaid to the display content that follow the camera. An example marker implementation and a tracking recovery method are presented. DMCT can measure pointing locations with sub-millimeter precision in large tracking volumes and computes 6-DoF camera poses for 3D interaction. 60 Hz update rate and 24 ms latency were achieved. DMCT's main limitation is the visible marker interfering with display content. In pointing effciency, the prototype is comparable to an OptiTrack system.
Realism and plausibility of computer controlled entities in entertainment software have been enhanced by adding both static personalities and dynamic emotions. Here a generic model is introduced that allows findings from real-life personality studies to be transferred to a computational model. Adaptive behavior patterns are enabled by introducing dynamic event-based emotions. The advantages of this model have been validated using a four-way crossroad in a traffic simulation. Driving agents using the introduced model enhanced by dynamics were compared to agents based on static personality profiles and simple rule-based behavior. The results show that adding a dynamic factor to agents improves perceivable plausibility and realism.
Improving the study entry supports students in a decisive phase of their university education. Implementing improvements is a change process and can only be successful if the relevant stakeholders are addressed and convinced. In the described Teaching Quality Pact project evaluation data is used as a mean to discuss in the university the situation of the study programs. As these discussions were based on empirical data rather than on opinion, it was possible to achieve an open discussion about measures that are implemented. The open discussion is maintained during the project when results of the measures taken are analyzed.
The contribution of the most common reciprocal translocation in childhood B-cell precursor leukemia t(12;21)(p13;q22) to leukemia development is still under debate. Direct as well as secondary indirect effects of the TEL-AML1 fusion protein are commonly recorded by using cell lines and patient samples, often bearing the TEL-AML1 fusion protein for decades. To identify direct targets of the fusion protein a short-term induction of TEL-AML1 is needed. We here describe in detail the experimental procedure, quality controls and contents of the ChIP, mRNA expression and SILAC datasets associated with the study published by Linka and colleagues in the Blood Cancer Journal [1] utilizing a short term induction of TEL-AML1 in an inducible precursor B-cell line model.
Adapting plans to changes in the environment by finding alternatives and taking advantage of opportunities is a common human behavior. The need for such behavior is often rooted in the uncertainty produced by our incomplete knowledge of the environment. While several existing planning approaches deal with such issues, artificial agents still lack the robustness that humans display in accomplishing their tasks. In this work, we address this brittleness by combining Hierarchical Task Network planning, Description Logics, and the notions of affordances and conceptual similarity. The approach allows a domestic service robot to find ways to get a job done by making substitutions. We show how knowledge is modeled, how the reasoning process is used to create a constrained planning problem, and how the system handles cases where plan generation fails due to missing/unavailable objects. The results of the evaluation for two tasks in a domestic service domain show the viability of the approach in finding and making the appropriate goal transformations.
Level-Synchronous Parallel Breadth-First Search Algorithms For Multicore and Multiprocessor Systems
(2014)
Breadth-First Search (BFS) is a graph traversal technique used in many applications as a building block, e.g.,~to systematically explore a search space. For modern multicore processors and as application graphs get larger, well-performing parallel algorithms are favourable. In this paper, we systematically evaluate an important class of parallel BFS algorithms and discuss programming optimization techniques for their implementation. We concentrate our discussion on level-synchronous algorithms for larger multicore and multiprocessor systems. In our results, we show that for small core counts many of these algorithms show rather similar behaviour. But, for large core counts and large graphs, there are considerable differences in performance and scalability influenced by several factors. This paper gives advice, which algorithm should be used under which circumstances.
Die nachhaltige Organisation des Verkehrs soll auf kostengünstige, umweltfreundliche und nutzerfreundlichere Nahverkehrskonzepte, die möglichst viele Bürger zur Nutzung des ÖPNV einladen, abzielen. Vor diesem Hintergrund ist es das Ziel dieses Beitrags, instrumentelle Ansatzpunkte für ein Nachhaltigkeitscontrolling in ÖPNV-Unternehmen aufzuzeigen. Hierzu werden nachfolgend die Berücksichtigung der Nachhaltigkeit bei Investitionsentscheidungen, das Carbon Accounting (Transparenz über CO2-Emissionen), die Integration der ökologischen, ökonomischen und sozialen Nachhaltigkeitsdimension bei der Berichterstattung und die Einbindung der genannten Instrumente in ein Managementsystem skizziert. Die Nachhaltigkeitsdimensionen Ökologie, Ökonomie und Soziales lassen sich gut mit Hilfe mehrdimensionaler, integrierter Managementsysteme in der Organisation verankern und systematisch in interne Strukturen und Prozesse einbetten. Integrierte Managementsysteme können so eine wichtige Voraussetzung für ein effizientes Nachhaltigkeitscontrolling sein.
Nachhaltigkeit als Megatrend. Die Arbeit der Weltkommission für Umwelt und Entwicklung unter Vorsitz von Brundtland machte bereits 1987 deutlich, dass v.a. das Management von Gemeingütern wie Ozeanen und der Atmosphäre, die Erhaltung des Weltfriedens, die weltweite Bevölkerungsentwicklung, die globale Ernährungssicherheit, die begrenzten Energieressourcen sowie die Folgen des Wirtschaftswachstums globale Herausforderungen darstellen, die nur durch eine nachhaltige Entwicklung gemeistert werden können.
GRI4-Guidelines
(2014)
In diesem Beitrag wird gezeigt, dass das Corporate Social Responsibility-Controlling (CSR-Controlling) im Zuge der neuen Berichterstattungsvorgaben der Global Reporting Initiative (GRI) vor neuen Herausforderungen steht. Die neue GRI-4-Version fordert über erweiterte und neue Pflichtstandardangaben die CSR-Umsetzung in höchster Niveauausprägung ein und setzt neue Maßstäbe an die CSR-Gütekriterien „Transparenz“ und „Rechenschaftslegung“ in der gesamten Supply Chain. In der Analyse werden die für den zukünftigen GRI-4-Berichtseinstieg erforderlichen Anpassungsschritte dargestellt und in einem GRI-3.1-versus-GRI-4-Vergleich indikatorenbezogen erläutert.
Purpose – The aim of the study is to investigate the implementation of corporate sustainability (CS) in the German real estate sector.
Design/methodology/approach – The authors begin by outlining the framework set by the European Union and the German Federal Government for companies wanting to be classified as sustainable. After this, the relevance of sustainability for German real estate companies is discussed. Their empirical section contains an international comparison. Finally, they present an analysis checking the implementation of CS for the main 135 German real estate companies.
Findings – The present analysis shows that German real estate companies compare well with their international counterparts, in 2012 representing 15 per cent of all real estate firms reporting on the basis of the Global Reporting Initiative. However, of the 135 companies in Germany surveyed, only a small proportion classify themselves as CS and CSR (corporate social responsibility) enterprises. This number could be rapidly increased by better documentation of companies’ commitment to sustainability.
Practical implications – The study’s importance lies in the overview it provides of CS activities in the German real estate industry. In addition, it provides hints on how companies can improve their documentation to classify as CSR enterprises. Although the analysis concentrates on Germany, the results are also relevant for companies in other European countries.
Die Formelsammlung zeigt die statistischen Formeln auf, die in den Wirtschaftswissenschaften notwendig von Bedarf sind. Sie ist interdisziplinär zielgerichtet und unterstützt sämtliche Bereiche der Ökonomik. Das Verständnis der Formeln und deren praktische Anwendung werden sinnvoll unterstützt durch nützliche Hilfen und Beispiele. Das Buch ist ein unverzichtbares Tool sowohl für den Studierenden als auch für den Verantwortlichen in Wirtschaft, Management, Verwaltung, Politik und Lehre.
Diese Formelsammlung zeigt die mathematischen Formeln auf, die in den
Wirtschaftswissenschaften notwendig von Bedarf sind. Sie ist interdisziplinär
zielgerichtet und unterstützt sämtliche Bereiche der Ökonomik. Das Verständnis der Formeln und deren praktische Anwendung werden sinnvoll unterstützt durch nützliche Hilfen und Beispiele. Das Buch ist ein unverzichtbares Tool sowohl für den Studierenden als auch für den Verantwortlichen in Wirtschaft, Management, Verwaltung, Politik und Lehre.
The case for basic human needs in coaching: A neuroscientific perspective - The SCOAP Coach Theory
(2014)
Verantwortliches Wirtschaften beschreibt die Betrachtung ökonomischer, ökologischer und sozialer Aspekte als ganzheitliches Konzept sowie deren Integration in die betriebswirtschaftliche Praxis mit dem Ziel, Wettbewerbsfähigkeit zu erhalten und Unternehmensrisiken zu minimieren. Verantwortliches Wirtschaften steht zudem für die Verpflichtung eines Unternehmens gegenüber seinen Stakeholdern sowie seiner Verantwortung gegenüber der Gesellschaft.
Masterkurs IT-Controlling
(2014)