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Mathematische Modellbildung zur Befahrbarkeitssimulation einer mobilen Tiefsee-Arbeitsmaschine
(1988)
Die Forderung nach dem systematischen Gewinnen von Tiefsee-Erzen, wie beispielsweise Manganknollen, mit selbstfahrenden Arbeitsmaschinen führt auf das schwierige Problem der Befahrbarkeit (Traffikabilität) des Tiefseebodens. Im vorliegenden Beitrag wird ein mathematisches Modell zur Befahrbarkeitssimulation einer ferngesteuerten Sammelmaschine vorgestellt. Am Beispiel eines, als Konstruktionsentwurf spezifizierten, aktiven Manganknollenkollektors im großtechnischen Maßstab werden die Modellannahmen und Voraussetzungen für den zugrundeliegenden Tiefseeboden, das Fahrwerk und die betrachteten Betriebszustände und Lastsituationen beschrieben. Mit Hilfe eines koordinatentransformierten Kräftesystems werden die Wechselbeziehungen zwischen Tiefseeboden und einem Vierraupen-Fahrwerk in einem Algorithmus zusammengefaßt. Als Anwendungsbeispiele werden mittels EDV-Programmierung interessierende Betriebszustände und Lastsituationen simuliert. Abschließend werden weitere Modellvarianten aufgezeigt.
Yams of the most widely differing nature are produced in textile mills. The production stages necessary for this are carried out with the aid of textile machines. Between these individual textile machines - from cards to spinning machines - sliver cans serve as a rule as transport containers, in which the sensitive sliver material is temporarily stored, and presented to the next production stage.
Der vorliegende Beitrag befaßt sich mit Automatisierungsmöglichkeiten in Textilbetrieben für konventionelle als auch für nichtkonventionelle Spinnverfahren. Aus der Vielzahl derzeit existenter Produktionsschritte werden die standardisierbaren Automatisierungskombinationen zwischen den eingesetzten Textilmaschinen von Karden bis zu Spinnautomaten herausgearbeitet. Hierfür werden die heute in der Praxis befindlichen Transportmittel aufgezeigt und, vom Materialfluß ausgehend, die Zuordnungsmöglichkeiten der Maschinen in den Produktionsschritten und deren Automatisierungsbausteine definiert. Durch eine ganzheitliche Betrachtungsweise werden je nach Automatisierungsziel die verschiedenen Lösungsansätze diskutiert und als Bausteine gegenübergestellt. Hierdurch werden neue mechatronische Automatisierungslösungen vorgestellt, die eine Integration von Produktionsschritten oder die Automatisierung zwischen den einzelnen Produktionsschritten ermöglicht.
Bond graph modelling was devised by Professor Paynter at the Massachusetts Institute of Technology in 1959 and subsequently developed into a methodology for modelling multidisciplinary systems at a time when nobody was speaking of object-oriented modelling. On the other hand, so-called object-oriented modelling has become increasingly popular during the last few years. By relating the characteristics of both approaches, it is shown that bond graph modelling, although much older, may be viewed as a special form of object-oriented modelling. For that purpose the new object-oriented modelling language Modelica is used as a working language which aims at supporting multiple formalisms. Although it turns out that bond graph models can be described rather easily, it is obvious that Modelica started from generalized networks and was not designed to support bond graphs. The description of bond graph models in Modelica is illustrated by means of a hydraulic drive. Since VHDL-AMS as an important language standardized and supported by IEEE has been extended to support also modelling of non-electrical systems, it is briefly investigated as to whether it can be used for description of bond graphs. It turns out that currently it does not seem to be suitable.
Multidisciplinary systems are described most suitably by bond graphs. In order to determine unnormalized frequency domain sensitivities in symbolic form, this paper proposes to construct in a systematic manner a bond graph from another bond graph, which is called the associated incremental bond graph in this paper. Contrary to other approaches reported in the literature the variables at the bonds of the incremental bond graph are not sensitivities but variations (incremental changes) in the power variables from their nominal values due to parameter changes. Thus their product is power. For linear elements their corresponding model in the incremental bond graph also has a linear characteristic. By deriving the system equations in symbolic state space form from the incremental bond graph in the same way as they are derived from the initial bond graph, the sensitivity matrix of the system can be set up in symbolic form. Its entries are transfer functions depending on the nominal parameter values and on the nominal states and the inputs of the original model. The sensitivities can be determined automatically by the bond graph preprocessor CAMP-G and the widely used program MATLAB together with the Symbolic Toolbox for symbolic mathematical calculation. No particular program is needed for the approach proposed. The initial bond graph model may be non-linear and may contain controlled sources and multiport elements. In that case the sensitivity model is linear time variant and must be solved in the time domain. The rationale and the generality of the proposed approach are presented. For illustration purposes a mechatronic example system, a load positioned by a constant-excitation d.c. motor, is presented and sensitivities are determined in symbolic form by means of CAMP-G/MATLAB.
Beitragsordnung der Studierendenschaft der Fachhochschule Bonn-Rhein-Sieg vom 16. Oktober 2003
(2003)
Although p27 plays a central role in cell cycle regulation, its role in breast cancer prognosis is controversial. Furthermore, the p27 gene CDKN1B carries a polymorphism with unknown functional relevance. This study was designed to evaluate p27 expression and p27 genotyping with respect to early breast cancer prognosis. 279 patients with infiltrating metastasis-free breast cancer were included in this study. p27 expression was determined in tumor tissue specimens from 261 patients by immunohistochemistry. From 108 patients, the CDKN1B genotype was examined by PCR and subsequent direct sequencing. 55.2% of the tumors were considered p27 positive. p27 expression did not correlate with any of the established parameters except for nodal involvement but significantly correlated to prolonged disease-free survival. In 35% of the tumors analyzed, the CDKN1B gene showed a polymorphism at codon 109 (V109G). The V109G polymorphism correlated with greater nodal involvement. In the node-negative subgroup, V109G correlated significantly with a shortened disease-free survival. In conclusion, the determination of the CDKN1B genotype might be a powerful tool for the prognosis of patients with early breast cancer.
Mit der Aufnahme des Lehrbetriebes im Wintersemester 1995/96 haben sich die Fachbereiche Wirtschaft in Sankt Augustin und Rheinbach die laufende Qualitätssicherung und Qualitätsverbesserung der Ausbildung zum Ziel gesetzt. Die Evaluierung der Lehre und des Studiums wurde frühzeitig implementiert. Der Fachbereich versteht den Lehr- und Evaluationsbericht als Instrument der selbst gesteuerten Qualitätssicherung.
Grundordnung der Fachhochschule Bonn-Rhein-Sieg (GrundO) vom 07. April 2005 (2. Änderungssatzung)
(2005)
Verwaltungs- und Benutzungsordnung der Hochschul- und Kreisbibliothek Bonn-Rhein-Sieg vom 18.07.2005
(2005)
2. Änderung der Geschäftsordnung für den Senat der Fachhochschule Bonn-Rein-Sieg vom 07. April 2005
(2005)
One of the issues that has been debated in the context of fairly open learning partnerships such as tandem learning has been whether and, if so, how much pedagogical support should be provided. Another issue is how do language learners who have grown accustomed to maximising their learning through comprehensible input and output make the transition to a reciprocal learning partnership where they are supposed to switch between the roles of learner and expert or resource. The three principles behind tandem learning are bilingualism; reciprocity; and learner autonomy. At Trinity College Dublin we have conducted extensive research into tandem learning in object-oriented Multiple User Domains (MOOs) since 1998. Of the three tandem principles, we found that balanced bilingualism, where both languages are used equally in the exchange, is difficult to achieve, particularly though not surprisingly in partnerships where L2 proficiency differs substantially. We think that technology, at least in MOOs, can contribute towards a solution to the problem. The bilingual tandem analyser (BTA) analyses MOO input while users are communicating and gives feedback to learners (and possibly teachers) on bilingualism in the exchange. Here, we discuss what attitudes towards bilingualism learners bring towards the tandem exchange and how they react to the BTA as a tool to monitor and regulate bilingualism: will learners perceive balanced bilingualism as a necessary principle of the partnership; what efforts do they make to keep the balance between the languages; how do they see the BTA: as an instrument of control, directed by the teacher; or do they perceive it as a useful tool to support their tandem exchanges?
Im Herbst 2005 hat Giso Deussen seine Tätigkeit als Professor für Medienpolitik und Medienethik an der Fachhochschule Bonn-Rhein-Sieg in Sankt Augustin beendet. Am 5. August war er 65 Jahre alt geworden. Fast 20 Jahre seines Berufslebens hat er in enger Verbindung mit "Communicatio Socialis" (ComSoc) verbracht, konkret: Er hat unserer Zeitschrift einen Teil seiner Arbeitskraft geschenkt. Von 1976 bis 1988 war er Mitglied des Redaktion genannten Fähnleins von nicht einmal sieben Aufrechten, die unter der organisatorischen Leitung von Josef Hosse und Franz-Josef Eilers die redaktionellen Lasten trug.
Grundordnung der Fachhochschule Bonn-Rhein-Sieg (GrundO) vom 20. April 2006 (3. Änderungssatzung)
(2006)
Background: Type 2 diabetes mellitus is associated with increased cardiovascular risk. One laboratory marker for cardiovascular risk assessment is high-sensitivity C-reactive protein (hsCRP).
Methods: This cross-sectional study attempted to analyze the association of hsCRP levels with insulin resistance, β-cell dysfunction and macrovascular disease in 4270 non-insulin-treated patients with type 2 diabetes [2146 male, 2124 female; mean age ±SD, 63.9±11.1years; body mass index (BMI) 30.1±5.5kg/m2; disease duration 5.4±5.6years; hemoglobin A1c (HbA1c) 6.8±1.3%]. It consisted of a single morning visit with collection of a fasting blood sample. Observational parameters included several clinical scores and laboratory biomarkers.
Results: Stratification into cardiovascular risk groups according to hsCRP levels revealed that 934 patients had low risk (hsCRP <1mg/L), 1369 patients had intermediate risk (hsCRP 1–3mg/L), 1352 patients had high risk (hsCRP >3–10mg/L), and 610 patients had unspecific hsCRP elevation (>10mg/L). Increased hsCRP levels were associated with other indicators of diabetes-related cardiovascular risk (homeostatic model assessment, intact proinsulin, insulin, BMI, β-cell dysfunction, all p<0.001), but showed no correlation with disease duration or glucose control. The majority of the patients were treated with diet (34.1%; hsCRP levels 2.85±2.39mg/L) or metformin monotherapy (21.1%; 2.95±2.50mg/L hsCRP). The highest hsCRP levels were observed in patients treated with sulfonylurea (17.0%; 3.00±2.43mg/L).
Conclusions: Our results indicate that hsCRP may be used as a cardiovascular risk marker in patients with type 2 diabetes mellitus and should be evaluated in further prospective studies.
The development of mobile robotic systems is a demanding task regarding its complexity, required resources and skills in multiple fields such as software development, artificial intelligence, mechanical design, electrical engineering, signal processing, sensor technology or control theory. This holds true particularly for soccer playing robots, where additional aspects like high dynamics, cooperation and high physical stress have to be dealt with. In robot competitions such as RoboCup, additional skills in the domains of team, project and knowledge management are of importance.