Refine
H-BRS Bibliography
- yes (74) (remove)
Departments, institutes and facilities
- Fachbereich Wirtschaftswissenschaften (21)
- Fachbereich Angewandte Naturwissenschaften (18)
- Fachbereich Ingenieurwissenschaften und Kommunikation (17)
- Fachbereich Informatik (16)
- Institut für funktionale Gen-Analytik (IFGA) (5)
- Fachbereich Sozialpolitik und Soziale Sicherung (4)
- Institut für Technik, Ressourcenschonung und Energieeffizienz (TREE) (4)
- Institute of Visual Computing (IVC) (4)
- Centrum für Entrepreneurship, Innovation und Mittelstand (CENTIM) (2)
- Institut für Cyber Security & Privacy (ICSP) (1)
Document Type
- Article (74) (remove)
Year of publication
- 2014 (74) (remove)
Keywords
- Exchangeable pairs (2)
- Stein’s method (2)
- apoptosis (2)
- parallel breadth-first search (2)
- 1-MCP (1)
- ARRs (1)
- Africa (1)
- Analytical Chemistry (1)
- Antibody Induced Arthritis (1)
- Area under the curve (1)
Matrix metalloproteinases (MMPs) are matrix-degrading enzymes that are over-expressed in joints of rheumatoid arthritis (RA) patients. However, the contribution of specific MMPs for the development of arthritic joints is unknown. This study is aimed at studying the role of matrix metalloproteinase-9 (MMP-9) in mice, using the K/BxN serum-transfer model of RA. Arthritis was induced in Balb/c mice by injecting K/BxN serum. Development of arthritis was followed in these mice by measuring ankle thickness and clinical index score. MMP-9 expression in the joints of mice killed at various time points during the disease progression was determined by gelatin zymography using ankle lysates. We found that MMP-9 expression increased with the severity of arthritis. Importantly MMP-9 deficient mice injected with K/BxN serum showed a milder form of arthritis in comparison to the control C57BL/6 mice injected with K/BxN serum. We therefore conclude that MMP-9 promotes arthritis in mice.
Das AD 2000-Regelwerk ist der dominierende Standard für den Druckbehälterbau in Deutschland. Die bereits in anderen europäischen Ländern verbreitete DIN EN 13445 findet kaum Berücksichtigung. Dies allerdings zu Unrecht, denn ein aktueller Vergleich, der im Rahmen einer Bachelorarbeit durchgeführte wurde, zeigt: Die EN 13445 ist zu einer echten Alternative gereift. Gerade das Hauptargument gegen eine Umstellung, die steigenden Kosten, ist längst überholt.
The contribution of the most common reciprocal translocation in childhood B-cell precursor leukemia t(12;21)(p13;q22) to leukemia development is still under debate. Direct as well as secondary indirect effects of the TEL-AML1 fusion protein are commonly recorded by using cell lines and patient samples, often bearing the TEL-AML1 fusion protein for decades. To identify direct targets of the fusion protein a short-term induction of TEL-AML1 is needed. We here describe in detail the experimental procedure, quality controls and contents of the ChIP, mRNA expression and SILAC datasets associated with the study published by Linka and colleagues in the Blood Cancer Journal [1] utilizing a short term induction of TEL-AML1 in an inducible precursor B-cell line model.
We investigated graphene structures grafted with fullerenes. The size of the graphene sheets ranges from 6400 to 640,000 atoms. The fullerenes (C60 and C240) are placed on top of the graphene sheets, using different impact velocities we could distinguish three types of impact. Furthermore, we investigated the changes of the vibrational properties. The modified graphene planes show additional features in the vibronic density of states.
We are happy to present you the special issue on Best Practice in Robot Software Development of the Journal on Software Engineering for Robotics! The spark for this special issue came during the eighth workshop on Software Development and Integration in Robotics (SDIR) at the 2013 IEEE International Conference on Robotics and Automation. The workshop focused on Robot Software Architectures, and the fruitful discussions made it clear that the design, development, and deployment of robot software is always an interplay between competing aspects. These are often couched in antagonistic pairs, such as dependability versus performance, and prominently include quality attributes as well as functional, nonfunctional, and application requirements.
The Project SupraMetall: Towards Commercial Fabrication of High-Temperature Superconducting Tapes
(2014)
GRI4-Guidelines
(2014)
In diesem Beitrag wird gezeigt, dass das Corporate Social Responsibility-Controlling (CSR-Controlling) im Zuge der neuen Berichterstattungsvorgaben der Global Reporting Initiative (GRI) vor neuen Herausforderungen steht. Die neue GRI-4-Version fordert über erweiterte und neue Pflichtstandardangaben die CSR-Umsetzung in höchster Niveauausprägung ein und setzt neue Maßstäbe an die CSR-Gütekriterien „Transparenz“ und „Rechenschaftslegung“ in der gesamten Supply Chain. In der Analyse werden die für den zukünftigen GRI-4-Berichtseinstieg erforderlichen Anpassungsschritte dargestellt und in einem GRI-3.1-versus-GRI-4-Vergleich indikatorenbezogen erläutert.