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DNA Sequencing
(2011)
Orešković and Porsdam Mann draw a distinction between ‘fast’ and ‘slow’ science. Whereas the latter involves rigorous and laborious adherence to the scientific method, the former represents the reality that much scientific work faces time pressures which at times force shortcuts. The distinction can be seen to operate in contemporary research into the coronavirus pandemic: whereas the development of vaccines and treatments usually requires years of meticulous laboratory work and several more years of clinical testing, the many millions suffering from the disease need a treatment now. However, by taking too many safeguards off the treatment discovery and testing pipelines, or by refusing to act in accordance with scientific advice, governments risk sacrificing the public’s trust not only in the government’s scientific bona fides but in the scientific process itself. This is a heavy price to pay, argue Orešković and Porsdam Mann, and point to evidence indicating that the success of Germany and Japan in combating COVID-19 can be traced to public trust in science and government, as well as scientifically-informed and respectful national leadership.
The development of mobile robotic systems is a demanding task regarding its complexity, required resources and skills in multiple fields such as software development, artificial intelligence, mechanical design, electrical engineering, signal processing, sensor technology or control theory. This holds true particularly for soccer playing robots, where additional aspects like high dynamics, cooperation and high physical stress have to be dealt with. In robot competitions such as RoboCup, additional skills in the domains of team, project and knowledge management are of importance.
Isolation of DNA and RNA
(2021)
Isolation of DNA and RNA
(2011)
The Decision Tree Procedure
(2024)
From September 2016 to February 2017, I did an internship at the University of Cape Coast, Ghana (UCC) as part of my studies in Business Administration at Hochschule Bonn-Rhein-Sieg, University of Applied Sciences, Germany (H-BRS). At H-BRS, an internship of five or six months (or, alternatively, one exchange semester) is an obligatory part of the curriculum so students get hands-on experience even before they enter the job market. My internship was also part of the intercontinental partnership between UCC and H-BRS, which has resulted in many different projects.
Insights from an Exergame-Based Training System for People with Dementia and Their Caregivers
(2020)
Mass Spectrometry: Pyrolysis
(2019)
Mesenchymal Stem Cells
(2020)
The European General Data Protection Regulation requires the implementation of Technical and Organizational Measures (TOMs) to reduce the risk of illegitimate processing of personal data. For these measures to be effective, they must be applied correctly by employees who process personal data under the authority of their organization. However, even data processing employees often have limited knowledge of data protection policies and regulations, which increases the likelihood of misconduct and privacy breaches. To lower the likelihood of unintentional privacy breaches, TOMs must be developed with employees’ needs, capabilities, and usability requirements in mind. To reduce implementation costs and help organizations and IT engineers with the implementation, privacy patterns have proven to be effective for this purpose. In this chapter, we introduce the privacy pattern Data Cart, which specifically helps to develop TOMs for data processing employees. Based on a user-centered design approach with employees from two public organizations in Germany, we present a concept that illustrates how Privacy by Design can be effectively implemented. Organizations, IT engineers, and researchers will gain insight on how to improve the usability of privacy-compliant tools for managing personal data.
Embryonic stem cells (ES) have the potential of long-term viability, selfrenewal and pluripotency which makes them interesting candidates for tissue engineering and gene therapy applications. On the other hand ethical and political issues arise while using theses cells and severe problems such as their tumorgenicity have not been solved yet. In the last couple of month a new source of cells with stem cell character was developed, the induced pluripotent stem cells (iPS). These cells are derived from differentiated adult cells via transduction of three transcription factors and show features similar to embryonic stem cells. Unfortunately, this includes the tumorgenicity which is even higher in those cells since the transcription factor transduction needed until now, is performed with retrovial vectors, which have a tumor potential on their own. Thus, adult stem cells are investigated extensively as alternative source of self-renewing cells. Human mesenchymal stem cells (HMSCs), which have in addition the advantage of potential autologous transplantation, can be found in various differentiated tissues since they are needed for maintenance and repair. They can be differentiated in chondrogenic, osteogenic, adipogenic and myogenic lineages which makes them an excellent tool for future tissue replacement strategies.
Managing the Work-Nonwork Interface: Personal Social Media Use as a Tool to Craft Boundaries?
(2021)
A soluble form of the complement receptor CD21 (sCD21) is shed from the lymphocyte surface. The sCD21 is able to bind all known ligands such as CD23, sCD23, Epstein-Barr virus and C3d in immune complexes. Here, we show the serum levels of sCD21 in sera the of antiphospholipid syndrome (APS) patients. Antiphospholipid syndrome is an autoimmune disorder in which autoantibodies cause heart attack, stroke and miscarriage. Antiphospholipid syndrome may appear as primary or in association with systemic lupus erythromatosus (SLE) and other autoimmune diseases. Here, we ask whether APS patients have different sCD21 titers compared to healthy persons and whether sCD21 levels correlate with the presence of anti-β2-GPI autoantibodies. We show that autoimmune APS patients have significantly reduced amounts of sCD21 in their sera, irrespective of the presence of anti-β2-GPI autoantibodies. In our APS patients cohort additional SLE, vasculities, DVT (deep vein thrombosis), fetal loss or thrombosis did not correlate to the reduced level of sCD21.
Actors
(2021)
Social protection is for many international organizations a state’s affair.1 While the state definitely plays an important role, the state is by far not the only actor and there is no predefined institutional arrangement of how social protection should be implemented. An exclusive focus on the state would therefore be short-sighted when assessing and comparing the performance of social protection systems. It is hence important to understand the mix of actors involved, the type of contribution they can make to social protection and their modes of cooperation. This contribution will therefore first sketch out the role and interplay of the main actors in social protection and then challenge some of the common assumptions made around how roles are best allocated in the social protection system concerning the providers of informal social protection, the private sector, civil society organizations (CSO) as well as international actors.
Social transfers
(2021)
Social transfers are on the rise in the Global South but they have also been in the centre of discussion in the Global North as an attractive instrument to buffer new risks and uncertainties in a changing world. They have experienced a dramatic change since the beginning of the new century, starting off as a revolutionary programmatic intervention in countries such as Mexico and Brazil or as a fledgling pilot programme in countries such as Zambia, Kenya and Malawi. They have now become a standard intervention across the globe, a truly global social policy as Hickey and Seekings (2019, 249) coined it. This global trend has been facilitated by donors’ strive to move away from ever recurring humanitarian actions, by increased pressure on donors to show aid effectiveness with the money finally reaching the most vulnerable as well as by international concerted actions such as the United Nations initiative of a global social protection floor.
While there is a standard set of instruments that can be used in social protection systems, this needs to be adapted and combined in different ways in order to serve different groups in society best. The needs of a young person who is just starting life and should not be trapped from birth in unfavourable socio-economic conditions are different from the social protection requirements of a retired person who has finished the active part of life and requires income and care security for an indefinite time period.
Designing a social protection system is of course not only a technical exercise but a very political affair. A systems approach to social protection is shaped by the political elites and the respective coalitions of change, the political institutions as well as the political system of a country. This explains why also seemingly similar countries in terms of their risk profile, poverty situation and economic situation can adopt very different social protection systems or make very different progress with respect to social protection expansion. Not only are the established welfare states of the Global North but also the nascent social protection systems in the Global South a testimony of this variety.
Heuristic Methods
(2024)
A Bicycle Simulator Based on a Motion Platform in a Virtual Reality Environment - FIVIS Project
(2007)
Any political phenomenon can only be properly understood in its broader con-text. Questions of international cooperation are thus necessarily framed by his-torical processes and relations of power. We therefore start our first discussion with an examination of the global ‘status quo’ and embed the topic of this pub-lication, ODA graduation, into the shifting world order, analysing current roles and settings in international relations and identifying changes in positions, sta-tus and categories. What are the overarching issues determining world politics and who are the old and the new actors driving them? What is the impact of these global shifts on international cooperation, especially development coop-eration? Of what relevance are roles, status and categories and what is the im-pact of changes in positions and relations? What challenges face multilateralism and what ways exist to maintain and renew strategic partnerships and shared values?
The UN Declaration on the Right to Development (UNDRTD) adopted in 1986 and the 2030 Agenda for Sustainable Development adopted in 2015 share a universal concept of development that refers both to individual and collective dimensions of prosperity and thus includes the rights of future generations.2 They thus offer a definition of the relationship between development and human rights that is very relevant for the 21st century. The core norm of the UNDRTD has been defined later as “the right of peoples and individuals to the constant improvement of their wellbeing and to a national and global enabling environment conducive to just, equitable, participatory and human-centred development respectful of all human rights”3.
In the last 5 years a close co-operation between the Bonn-Rhein-Sieg University of Applied Sciences and the Philips Research Laboratories in Aachen has been established. In this article I want to report on the co-operation of the Department of Electrical Engineering, Mechanical Engineering and Technical Journalism with Philips. Besides a number of diploma theses on the field of water treatment with new discharge lamps, power electronics and modelling of electromagnetic field configurations, there is running also an activity on a new generation of highly efficient light sources based on molecular discharges.
While Anglo-Saxon HEIs focus on a strong educational background and personal development of students, the German system, in particular Universities of Applied Sciences, emphasize employability through the transfer of job-related professional and soft skills. In this context, learning by practical application of skills has become an important instrument. Concepts for linking theory and application include research-based learning, practical internships or service learning – methods, which also maintain high standards of academic education.
Introduction
(2018)
This handbook describes the processes and success factors of marketoriented university services to the non-academic world, and the processes to integrate these services into teaching. It aims to highlight benchmark examples from Africa and Germany in order to outline motivational factors, influencing aspects, as well as drivers and barriers to applied university services in developing countries.