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Communicating Sequential Processes (CSP) [7] is a calculus for concurrent systems that has been the basis of subject-oriented business process management (S-BPM) [4]. We use CSPm -- a machine readable dialect of CSP -- to create a sequence of models for a case study on an "Automated Teller Machine" [1]. We use the refinement checker FDR2 to prove that certain models are correct implementations of specifications.
Aktuelle Studien prognostizieren bis zum Jahr 2018 etwa 27.000 Nachfolgen in deutschen Familienunternehmen pro Jahr. Dieses Buch unterstützt Sie bei der Herausforderung Unternehmensnachfolge in allen wichtigen betriebswirtschaftlichen, rechtlichen, organisatorischen, steuerlichen und psychologischen Fragen und bei der Umsetzung Ihrer individuellen Nachfolgestrategie.
Die Vielzahl der Möglichkeiten, um mit Kunden in den Dialog zu treten, ist erheblich gestiegen. Unternehmen sind deshalb gefordert, die verschiedenen Kontaktkanäle mit ihren Kunden systematisch zu managen. Im Mittelpunkt steht dabei der Informations- und Entscheidungsprozess des Kunden, der als Customer Journey bezeichnet wird. Diese Journey ist definiert als Prozess zwischen dem ersten Kaufimpuls und der Kaufentscheidung. Dieser Prozess ist charakterisiert von der Nutzung verschiedener Medien bzw. Kontaktkanäle. Kunden nutzen die Kontaktkanäle, die ihnen in der aktuellen Situation als sehr einfach bzw. bequem erscheinen und zu ihren spezifischen Anliegen (Fragen zum Produkt, Bestellung etc.) passen. Erfahrungen zeigen, dass sich zwar Grundmuster identifizieren lassen, ansonsten die Wege der Kunden jedoch sehr individuell sein können.
We present GEM-NI -- a graph-based generative-design tool that supports parallel exploration of alternative designs. Producing alternatives is a key feature of creative work, yet it is not strongly supported in most extant tools. GEM-NI enables various forms of exploration with alternatives such as parallel editing, recalling history, branching, merging, comparing, and Cartesian products of and for alternatives. Further, GEM-NI provides a modal graphical user interface and a design gallery, which both allow designers to control and manage their design exploration. We conducted an exploratory user study followed by in-depth one-on-one interviews with moderately and highly skills participants and obtained positive feedback for the system features, showing that GEM-NI supports creative design work well.
An Empirical Evaluation of the Received Signal Strength Indicator for fixed outdoor 802.11 links
(2015)
For the evaluation of the received signal strength indication (RSSI) a different methodology compared to previous publications is introduced in this paper by exploiting a spectral scan feature of recent Qualcomm Atheros WiFi NICs. This method is compared to driver reports and to an industrial grade spectrum analyzer. During the conducted outdoor experiments a decreased scattering of the RSSI compared to previous publications is observed. By applying well-known mathematical tests for normality it is possible to show that the RSSI does not follow a normal distribution in a line-of-sight outdoor environment. The evaluated spectral scan features offers additional possibilities to develop interference classifiers which is an important step for frequency allocation in long-distance 802.11 networks.
Die Rückkehr ins Erwerbsleben (Return to Work, RTW) wird für onkologische Rehabilitanden zunehmend zum zentralen Behandlungsziel, wodurch auch die Bereitstellung spezifischer berufsorientierter Maßnahmen an Bedeutung gewinnt (z. B. Mehnert, Koch, 2012). Die Überprüfung der Behandlungsergebnisse solcher Maßnahmen stellt einen wichtigen Baustein des Qualitätsmanagements der Rehabilitationseinrichtungen dar. Im Rahmen der „Reha-QM-Outcome-Studie“ des Qualitätsverbundes Gesundheit und der Deutschen Rentenversicherung Baden-Württemberg (Nübling et al., 2014) wurde daher ein besonderes Augenmerk auf das Outcome und die RTW-Quote der onkologischen Patienten, auch im Vergleich zu anderen Hauptindikationen, gelegt.
Hox genes are an evolutionary highly conserved gene family. They determine the anterior-posterior body axis in bilateral organisms and influence the developmental fate of cells. Embryonic stem cells are usually devoid of any Hox gene expression, but these transcription factors are activated in varying spatial and temporal patterns defining the development of various body regions. In the adult body, Hox genes are among others responsible for driving the differentiation of tissue stem cells towards their respective lineages in order to repair and maintain the correct function of tissues and organs. Due to their involvement in the embryonic and adult body, they have been suggested to be useable for improving stem cell differentiations in vitro and in vivo. In many studies Hox genes have been found as driving factors in stem cell differentiation towards adipogenesis, in lineages involved in bone and joint formation, mainly chondrogenesis and osteogenesis, in cardiovascular lineages including endothelial and smooth muscle cell differentiations, and in neurogenesis. As life expectancy is rising, the demand for tissue reconstruction continues to increase. Stem cells have become an increasingly popular choice for creating therapies in regenerative medicine due to their self-renewal and differentiation potential. Especially mesenchymal stem cells are used more and more frequently due to their easy handling and accessibility, combined with a low tumorgenicity and little ethical concerns. This review therefore intends to summarize to date known correlations between natural Hox gene expression patterns in body tissues and during the differentiation of various stem cells towards their respective lineages with a major focus on mesenchymal stem cell differentiations. This overview shall help to understand the complex interactions of Hox genes and differentiation processes all over the body as well as in vitro for further improvement of stem cell treatments in future regenerative medicine approaches.
A major challenge modern society has to face is the increasing need for tissue regeneration due to degenerative diseases or tumors, but also accidents or warlike conflicts. There is great hope that stem cell-based therapies might improve current treatments of cardiovascular diseases, osteochondral defects or nerve injury due to the unique properties of stem cells such as their self-renewal and differentiation potential. Since embryonic stem cells raise severe ethical concerns and are prone to teratoma formation, adult stem cells are still in the focus of research. Emphasis is placed on cellular signaling within these cells and in between them for a better understanding of the complex processes regulating stem cell fate. One of the oldest signaling systems is based on nucleotides as ligands for purinergic receptors playing an important role in a huge variety of cellular processes such as proliferation, migration and differentiation. Besides their natural ligands, several artificial agonists and antagonists have been identified for P1 and P2 receptors and are already used as drugs. This review outlines purinergic receptor expression and signaling in stem cells metabolism. We will briefly describe current findings in embryonic and induced pluripotent stem cells as well as in cancer-, hematopoietic-, and neural crest-derived stem cells. The major focus will be placed on recent findings of purinergic signaling in mesenchymal stem cells addressed in in vitro and in vivo studies, since stem cell fate might be manipulated by this system guiding differentiation towards the desired lineage in the future.
Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors
(2015)
Grundlagen des Marketings
(2015)
Work in progress: Starter-project for first semester students to survey their engineering studies
(2015)
Understanding the Internet of Things: A Conceptualisation of Business-to-Thing (B2T) Interactions
(2015)
Kaum ein anderes Segment im Gesundheitswesen in Deutschland steht so im Fokus der Qualitätssicherung wie die medizinische Rehabilitation. So sind leitliniengetreue Therapien oder ausgereifte Zertifizierungsverfahren längst existenzielle Belegungsvoraussetzungen für die Rehabilitationseinrichtungen. Ohne ein funktionierendes Qualitätsmanagementsystem darf eine Rehabilitationsklinik nicht belegt werden (§20 SGB IX) – das ist einmalig im Gesundheitssystem. Die Rehabilitationskliniken sind damit Vorreiter in Sachen Qualität im Gesundheitswesen.
Die Komplexität des Geschehens in der Sozialversicherung nimmt stetig zu. Zur Lösung der sich daraus ergebenden Problemstellungen sind auf dem Feld der Sozialversicherung eine Vielzahl von Disziplinen (u. a. Rechtswissenschaft, Ökonomie, Medizin, Informatik, Psychologie, Politik- und Sozialwissenschaft und das Case Management) aktiv. Im Sinne eines "Aufbruchs zur Sozialversicherungswissenschaft", die als Integrationswissenschaft Grenzen überwinden will, diskutieren in diesem Handbuch 86 Autorinnen und Autoren aus Wissenschaft und Praxis Themen aus dem bzw. zum System der Sozialversicherung und zeigen Wege auf, die sich durch angewandte interdisziplinäre Zusammenarbeit eröffnen.
Sweet sorghum (Sorghum bicolor (L.) moench), a crop that is grown by subsistence farmers in Zimbabwe was used to extract silica gel in order to assess its possible use as a raw material for the production of silica-based products. The gel was prepared from sodium silicate extracted from sweet sorghum bagasse ash by sodium hydroxide leaching. Results show that maximum yield can be obtained at pH 5 and with 3 M sodium concentration. The silica gel prepared at optimum pH 5 had a bulk density of 0.5626 g/cm3 and anestimated porosity of 71.87%. Silica gel aged over 10 h had improved moisture adsorption properties. X-ray fluorescence (XRF) determinations show that the silica content in the ash is 40.1%. Characterization of sweet sorghum ash and silica gels produced at pH 5, 7 and 8.5 by Fourier Transform Infrared spectroscopy gave absorption bands similar to those reported by other researchers.Transmission electron micrographs show that silica prepared under optimum conditions is amorphous and consisted of irregular particles. Sweet sorghum proved to be a potential low cost raw material for the production of silica gel.
Unternehmensführung
(2015)
Dieses Buch führt Sie systematisch und leicht verständlich in das Thema Unternehmensführung ein. Es konzentriert sich bewusst auf die wichtigsten Fragen des Handelns als verantwortlicher Manager in der Unternehmensführung bzw. in der Bereichs- oder Abteilungsverantwortung. Dabei werden ausgewählte Probleme aus dem Management entwickelt und anschließend anhand von Praxisbeispielen erläutert. (Verlagsangaben)
Unternehmen agieren in einem dynamischen Umfeld mit hoher Komplexität und Unsicherheit. Um dabei langfristig wettbewerbsfähig zu bleiben, ist eine kontinuierliche Optimierung der Prozesse erforderlich. Eine konsequente Prozessorientierung wird daher seit langem angestrebt. Zur Ermittlung des aktuellen Standes der Prozessorganisation in deutschen Unternehmen hat die Gesellschaft für Organisation e. V. (gfo) eine Studie durchführen lassen, deren erste Ergebnisse hier vorgestellt werden.
[Context and motivation] Communication in distributed software development is usually supported by issue tracking systems. Within these systems, most of the communication is stored as unstructured natural language text. The natural language text, however, contains much information with respect to requirements management, e.g. discussion, clarification and prioritization of features, bugs, and refactorings. [Question] This paper investigates the information stored in the issue tracking systems of four different open-source projects. It categorizes the text and reports on the distribution of issue types and information types. [Principal ideas/results] A manual analysis of 80 issues, using a grounded approach, is conducted to derive a taxonomy of issue types and information types. Subsequently, the taxonomy is used as a codebook, to manually categorize and structure the text in another 120 issues. [Contribution] The first contribution of this paper is the taxonomy of issue and information types and the second contribution is an in-depth analysis of the natural language data and the communication. This analysis showed, for example, that information with respect to prioritization and scheduling can be found in natural language data, whether the ITS supports such tasks in a structured way or not.
Comparison of the subject-oriented and the Petri net based approach for business process automation
(2015)
The subject-oriented modelling approach [5] significally differs from the classic Petri net based approach of many business process modeling languages like EPC [9], Business Process Model and Notation (BPMN) [11], and also Yet Another Workflow Language (YAWL) [10]. In this work, we compare the two approaches by modeling a case study called "Procure to Pay"[3], a typical business process where some equipment for a construction site is rented and finally paid. The case study is not only modelled but also automated using the Metasonic Suite for the subject-oriented and YAWL for the Petri net based approach.
This book presents bond graph model-based fault detection with a focus on hybrid system models. The book addresses model design, simulation, control and model-based fault diagnosis of multidisciplinary engineering systems. The text beings with a brief survey of the state-of-the-art, then focuses on hybrid systems. The author then uses different bond graph approaches throughout the text and provides case studies.