Refine
H-BRS Bibliography
- no (115) (remove)
Departments, institutes and facilities
Document Type
- Conference Object (48)
- Article (28)
- Part of a Book (25)
- Patent (4)
- Lecture (3)
- Contribution to a Periodical (2)
- Book (monograph, edited volume) (1)
- Conference Proceedings (1)
- Doctoral Thesis (1)
- Master's Thesis (1)
Year of publication
- 2014 (115) (remove)
Has Fulltext
- no (115)
Keywords
- Human Factors In Software Design (2)
- Nachhaltigkeit (2)
- Ad Hoc Kommunikation (1)
- Adaptive Streaming (1)
- Barriers (1)
- Biotin (1)
- Cloud (1)
- Cloud Security (1)
- Computer Aided Software Engineering (1)
- Computer Security (1)
Methylmalonic and propionic acidemia (MMA/PA) are inborn errors of metabolism characterized by accumulation of propionic acid and/or methylmalonic acid due to deficiency of methylmalonyl-CoA mutase (MUT) or propionyl-CoA carboxylase (PCC). MMA has an estimated incidence of ~ 1: 50,000 and PA of ~ 1:100'000 -150,000. Patients present either shortly after birth with acute deterioration, metabolic acidosis and hyperammonemia or later at any age with a more heterogeneous clinical picture, leading to early death or to severe neurological handicap in many survivors. Mental outcome tends to be worse in PA and late complications include chronic kidney disease almost exclusively in MMA and cardiomyopathy mainly in PA. Except for vitamin B12 responsive forms of MMA the outcome remains poor despite the existence of apparently effective therapy with a low protein diet and carnitine. This may be related to under recognition and delayed diagnosis due to nonspecific clinical presentation and insufficient awareness of health care professionals because of disease rarity.
Residential and commercial buildings are responsible for about 40% of the EU’s total energy consumption. However, conscious, sustainable use of this limited resource is hampered by a lack of visibility and materiality of consumption. One of the major challenges is enabling consumers to make informed decisions about energy consumption, thereby supporting the shift to sustainable actions. With the use of Energy-Management-Systems it is possible to save up to 15%. In recent years, design approaches have greatly diversified, but with the emergence of ubiquitous- and context-aware computing, energy feedback solutions can be enriched with additional context information. In this study, we present the concept “room as a context” for eco-feedback systems. We investigate opportunities of making current state-of-the-art energy visualizations more meaningful and demonstrate which new forms of visualizations can be created with this additional information. Furthermore, we developed a prototype for android-based tablets, which includes some of the presented features to study our design concepts in the wild.
Simulation of thermal behavior during friction stir welding process for predicting residual stresses
(2014)
Hydrogen sulfide (H2S) is well known as a highly toxic environmental chemical threat. Prolonged exposure to H2S can lead to the formation of pulmonary edema. However, the mechanisms of how H2S facilitates edema formation are poorly understood. Since edema formation can be enhanced by an impaired clearance of electrolytes and, consequently, fluid across the alveolar epithelium, it was questioned whether H2S may interfere with transepithelial electrolyte absorption. Electrolyte absorption was electrophysiologically measured across native distal lung preparations (Xenopus laevis) in Ussing chambers. The exposure of lung epithelia to H2S decreased net transepithelial electrolyte absorption. This was due to an impairment of amiloride-sensitive sodium transport. H2S inhibited the activity of the Na+/K+-ATPase as well as lidocaine-sensitive potassium channels located in the basolateral membrane of the epithelium. Inhibition of these transport molecules diminishes the electrochemical gradient which is necessary for transepithelial sodium absorption. Since sodium absorption osmotically facilitates alveolar fluid clearance, interference of H2S with the epithelial transport machinery provides a mechanism which enhances edema formation in H2S-exposed lungs.