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Departments, institutes and facilities
- Fachbereich Wirtschaftswissenschaften (23)
- Institut für funktionale Gen-Analytik (IFGA) (14)
- Fachbereich Informatik (11)
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- Fachbereich Ingenieurwissenschaften und Kommunikation (5)
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Document Type
- Article (41)
- Book (monograph, edited volume) (15)
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Year of publication
- 2002 (94) (remove)
Keywords
- Lehrbuch (5)
- Unternehmen (3)
- bitter pit (3)
- calcium chloride (3)
- cuticular penetration (3)
- Theoretische Informatik (2)
- Unternehmenspolitik (2)
- Adiabates Kühlsystem (1)
- Anwendungssystem (1)
- Aufsatzsammlung (1)
Unternehmensführung
(2002)
Theoretische Informatik
(2002)
Eine anschauliche Einführung in die klassischen Themenbereiche der Theoretischen Informatik für Studierende der Informatik im Haupt- und Nebenfach. Die Autoren wählen einen Ansatz, der durch zahlreiche ausgearbeitete Beispiele auch LeserInnen mit nur elementaren Mathematikkenntnissen den Zugang zu Berechenbarkeit, Komplexitätstheorie und formalen Sprachen ermöglicht. Die mathematischen Konzepte werden sowohl formal eingeführt als auch informell erläutert und durch grafische Darstellungen veranschaulicht. Das Buch umfasst den Lehrstoff einführender Vorlesungen in die Theoretische Informatik und bietet zahlreiche Übungsaufgaben zu jedem Kapitel an. (Verlagsangaben)
Reggie-1/flotillin-2 is a plasma membrane-associated cytoplasmic protein, which defines non-caveolar raft microdomains. Reggie-1/flotillin-2 is enriched in detergent insoluble (TX100) membrane fractions (DIG), co-localizes with activated GPI-linked proteins and the fyn-kinase in neurons and T cells, and thus apparently participates in the assembly of protein complexes essential for signal transduction. In T cells activated by crosslinking the GPI-linked protein Thy-1 or by crosslinking the ganglioside GM1, reggie-1/flotillin-2 co-localizes with the T cell receptor. To determine whether reggie-1/flotillin-2 is also expressed in B cells, primary B cells from human blood and cell lines representing the developmental stages of pro, pre, mature and plasma B cells were analyzed by Western blotting, RT-PCR and immunofluorescence. Here, we show that reggie-1/flotillin-2 is expressed throughout B cell development, as well as in primary B cells, purified by cell sorting. On non-activated mature B cell Raji cell line we found reggie-1/flotillin-2 are exclusively in the detergent (TX100) insoluble membrane fractions that are staining positive for the raft marker GM1. Immunofluorescence microscopy showed that reggie-1/flotillin-2 is localized at the plasma membrane and marks intracellular spots in PBMCs. Confocal co-localization studies showed that reggie-1/flotillin-2 is associated with the plasma membrane, and the centrosomes (microtubule organizing centers) in these PBMCs. Comparison of reggie-1/flotillin-2 cDNA sequences with the genomic sequence database allowed us to determine the exon/intron structures in mouse and human. The gene organizations are highly conserved suggesting an important function of reggie-1/flotillin-2. Since reggie/flotillin proteins co-cluster with the T cell receptor and fyn kinases upon T cell stimulation, our findings of reggie-1/flotillin-2 in B cells suggest a similar role in B cell function.
We examine the effect of nanometer-sized aircraft-induced aqueous sulfuric acid (H2SO4/H2O) particles on atmospheric ozone as a function of temperature. Our calculations are based on a previously derived parameterization for the regional-scale perturbations of the sulfate surface area density due to air traffic in the North Atlantic Flight Corridor (NAFC) and a chemical box model. We confirm large scale model results that at temperatures T>210 K additional ozone loss -- mainly caused by hydrolysis of BrONO2 and N2O5 -- scales in proportion with the aviation-produced increase of the background aerosol surface area. However, at lower temperatures (< 210 K) we isolate two effects which efficiently reduce the aircraft-induced perturbation: (1) background particles growth due to H2O and HNO3 uptake enhance scavenging losses of aviation-produced liquid particles and (2) the Kelvin effect efficiently limits chlorine activation on the small aircraft-induced droplets by reducing the solubility of chemically reacting species. These two effects lead to a substantial reduction of heterogeneous chemistry on aircraft-induced volatile aerosols under cold conditions. In contrast we find contrail ice particles to be potentially important for heterogeneous chlorine activation and reductions in ozone levels. These features have not been taken into consideration in previous global studies of the atmospheric impact of aviation. Therefore, to parameterize them in global chemistry and transport models, we propose the following parameterisation: scale the hydrolysis reactions by the aircraft-induced surface area increase, and neglect heterogeneous chlorine reactions on liquid plume particles but not on ice contrails and aircraft induced ice clouds.
Strategien zur Einführung und Implementierung betriebswirtschaftlicher Standardanwendungssoftware
(2002)
A way of combining a relatively new sensor-technology, that is optical analog VLSI devices, with a standard digital omni-directional vision system is investigated. The sensor used is a neuromorphic analog VLSI sensor that estimates the global visual image motion. The sensor provides two analog output voltages that represent the components of the global optical flow vector. The readout is guided by an omni-directional mirror that maps the location of the ball and directs the robot to align its position so that a sensor-actuator module that includes the analog VLSI optical flow sensor can be activated. The purpose of the sensor-actuator module is to operate with a higher update rate than the standard vision system and thus increase the reactivity of the robot for very specific situations. This paper will demonstrate an application example where the robot is a goalkeeper with the task of defending the goal during a penalty kick.
Screening in clinical trials
(2002)