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- 1997 (79) (remove)
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Information spielt in jeder arbeitsteilig organisierten Volkswirtschaft eine wichtige Rolle. Nur durch den Austausch von Informationen ist eine Koordination von Leistungserstellungs- und Allokationsprozessen möglich. "Alles das, was ... geteilt, gespalten oder weiter untergliedert – mit einem Wort: was aufgelöst worden ist, muß durch ein System von Information und Kommunikation wieder verbunden werden" (1). Ein Betrieb ist ohne Informationsfluß im Inneren und nach außen schlichtweg nicht funktionsfähig.
改进科技教育和科研工作--一位德国学者的几点看法
(1997)
Benches and CAVEs
(1997)
Expression of the apoptosis-inhibitory protein Bcl-2 has frequently been detected in human cancer including mammary carcinoma. The functional significance of its expression has been well established in experimental tumors of the lymphoid system, however, remains to be elucidated for epithelial tumors. In order to assess the role of Bcl-2 in mammary tumorigenesis we have generated WAP-bcl-2 transgenic mice. The strong overexpression of Bcl-2 in lactating mammary glands was preserved during early postlactational involution and apoptosis of alveolar epithelial cells was prevented without influencing the dedifferentiation of the milk-producing epithelium. Although Bcl-2 overexpression was not sufficient to induce spontaneous tumors it, however, led to an accelerated development of MMTV myc transgene-induced mammary tumors. In the mammary glands of MMTV myc transgenic mice, a high proportion of apoptotic cells was detected which was significantly reduced in the mammary glands of WAP-bcl-2/ MMTV myc double transgenic mice. Taken together, these results suggest that Bcl-2 contributes to mammary tumorigenesis by inhibiting apoptosis.
Der virtuelle Wetterfrosch
(1997)