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Dual Dynamics (DD) is a mathematical model of a behavior control system for mobile autonomous robots. Behaviors are specified through differential equations; forming a global dynamical system made of behavior subsystems which interact in a number of ways. DD models can be directly compiled into executable code. The article (i) explains the model; (ii) sketches the Dual Dynamics Designer (DDD) environment that we use for the design; simulation; implementation and documentation; and (iii) illustrates our approach with the example of kicking a moving ball into a goal.
GMD-Robots
(2001)
GMD-Robots
(2002)
Traffic simulations for virtual environments are concerned with the behavior of individual traffic participants. The complexity of behavior in these simulations is often rather simple to abide by the constraints of processing resources. In sophisticated traffic simulations, the behavior of individual traffic participants is also modeled, but the focus lies on the overall behavior of the entire system, e.g. to identify possible bottle necks of traffic flow [8].
Although p27 plays a central role in cell cycle regulation, its role in breast cancer prognosis is controversial. Furthermore, the p27 gene CDKN1B carries a polymorphism with unknown functional relevance. This study was designed to evaluate p27 expression and p27 genotyping with respect to early breast cancer prognosis. 279 patients with infiltrating metastasis-free breast cancer were included in this study. p27 expression was determined in tumor tissue specimens from 261 patients by immunohistochemistry. From 108 patients, the CDKN1B genotype was examined by PCR and subsequent direct sequencing. 55.2% of the tumors were considered p27 positive. p27 expression did not correlate with any of the established parameters except for nodal involvement but significantly correlated to prolonged disease-free survival. In 35% of the tumors analyzed, the CDKN1B gene showed a polymorphism at codon 109 (V109G). The V109G polymorphism correlated with greater nodal involvement. In the node-negative subgroup, V109G correlated significantly with a shortened disease-free survival. In conclusion, the determination of the CDKN1B genotype might be a powerful tool for the prognosis of patients with early breast cancer.
Cysticfibrosis (CF) arises from mutations in the CF transmembrane conductance regulator (CFTR) gene, resulting in progressiveand life-limiting respiratory disease. R751L is a rare CFTR mutation that is poorly characterized. Our aims were to describe theclinical and molecular phenotypes associated with R751L. Relevant clinical data were collected from three heterozygote individu-als harboring R751L (2 patients with G551D/R751L and 1 with F508del/R751L). Assessment of R751L-CFTR function was made inprimary human bronchial epithelial cultures (HBEs) andXenopusoocytes. Molecular properties of R751L-CFTR were investigatedin the presence of known CFTR modulators. Although sweat chloride was elevated in all three patients, the clinical phenotypeassociated with R751L was mild. Chloride secretion in F508del/R751L HBEs was reduced compared with non-CF HBEs and asso-ciated with a reduction in sodium absorption by the epithelial sodium channel (ENaC). However, R751L-CFTR function inXenopusoocytes, together with folding and cell surface transport of R751L-CFTR, was not different from wild-type CFTR. Overall,R751L-CFTR was associated with reduced sodium chloride absorption but had functional properties similar to wild-type CFTR.This is thefirst report of R751L-CFTR that combines clinical phenotype with characterization of functional and biological proper-ties of the mutant channel. Our work will build upon existing knowledge of mutations within this region of CFTR and, importantly,inform approaches for clinical management. Elevated sweat chloride and reduced chloride secretion in HBEs may be due to al-ternative non-CFTR factors, which require further investigation.
BWL-Klausuren für Dummies
(2019)
Using virtual environment systems for road safety education requires a realistic simulation of road traffic. Current traffic simulations are either too restricted in their complexity of agent behavior or focus on aspects not important in virtual environments. More importantly, none of them are concerned with modeling misbehavior of traffic participants which is part of every-day traffic and should therefore not be neglected in this context. We present a concept for a traffic simulation that addresses the need for more realistic agent behavior with regard to road safety education. The two major components of this concept are a simulation of persistent agents which minimizes computational overhead and a model of cognitive processes of human drivers combined with psychological personality profiles to allow for individual behavior and misbehavior.
Traditionally traffic simulations are used to predict traffic jams, plan new roads or highways, and estimate road safety. They are also used in computer games and virtual environments. There are two general concepts of modeling traffic: macroscopic and microscopic modeling. Macroscopic traffic models take vehicle collectives into account and do not consider individual vehicles. Parameters like average velocity and density are used to model the flow of traffic. In contrast, microscopic traffic models consider each vehicle individually. Therefore, vehicle specific parameters are of importance, e.g. current velocity, desired velocity, velocity difference to the lead vehicle, individual time gap.
Trusted EPC Administration
(2009)
RFID-Transponder dienen der Identifizierung von Produkten, der Zuordnung von Produkten zu Personen, der Fälschungssicherheit und weiteren Anwendungsgebieten. Durch RFID-Transponder sollen Technologien wie z.B. der Barcode (teilweise) abgelöst werden. Einige Unternehmen sehen eine Koexistenz zwischen den Technologien, da die alte Technologie zur Zeit noch kostengünstiger ist. Einige Branchen, wie z.B. Produktion, Logistik und Handel, können von der Technologie profitieren. Die RFID-Transponder bringen gegenüber alten Technologien viele Vorteile. RFID ermöglicht die Verarbeitung eines größeren Datenvolumens, es ist kein direkter Sichtkontakt zum Lese-/Schreibgerät erforderlich und mehrere Transponder können gleichzeitig ausgewertet werden. Business-to-Business (B2B) Anwender erhoffen sich einen effizienteren und transparenteren Beschaffungsprozess, welcher im Rahmen des Supply-Chain-Managements Vorteile bringen kann. Diese Arbeit legt ihren Schwerpunkt auf die Echtzeitüberwachung während des gesamten Produktlebenszyklus. Zur weltweit eindeutigen Identifikation von Objekten werden dazu in RFID-Transpondern item-level Identifikationsnummern wie der EPC (Electronic Product Code) verwendet.