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Novel Automated Three-Dimensional Genome Scanning Based on the Nuclear Architecture of Telomeres
(2011)
Nowadays, we input text not only on stationary devices, but also on handheld devices while walking, driving, or commuting. Text entry on the move, which we term as nomadic text entry, is generally slower. This is partially due to the need for users to move their visual focus from the device to their surroundings for navigational purposes and back. To investigate if better feedback about users' surroundings on the device can improve performance, we present a number of new and existing feedback systems: textual, visual, textual & visual, and textual & visual via translucent keyboard. Experimental comparisons between the conventional and these techniques established that increased ambient awareness for mobile users enhances nomadic text entry performance. Results showed that the textual and the textual & visual via translucent keyboard conditions increased text entry speed by 14% and 11%, respectively, and reduced the error rate by 13% compared to the regular technique. The two methods also significantly reduced the number of collisions with obstacles.
This thesis work presents the implementation and validation of image processing problems in hardware to estimate the performance and precision gain. It compares the implementation for the addressed problem on a Field Programmable Gate Array (FPGA) with a software implementation for a General Purpose Processor (GPP) architecture. For both solutions the implementation costs for their development is an important aspect in the validation. The analysis of the flexibility and extendability that can be achieved by a modular implementation for the FPGA design was another major aspect. This work is based upon approaches from previous work, which included the detection of Binary Large OBjects (BLOBs) in static images and continuous video streams [13, 15]. One addressed problem of this work is the tracking of the detected BLOBs in continuous image material. This has been implemented for the FPGA platform and the GPP architecture. Both approaches have been compared with respect to performance and precision. This research project is motivated by the MI6 project of the Computer Vision research group, which is located at the Bonn-Rhein-Sieg University of Applied Sciences. The intent of the MI6 project is the tracking of a user in an immersive environment. The proposed solution is to attach a light emitting device to the user for tracking the created light dots on the projection surface of the immersive environment. Having the center points of those light dots would allow the estimation of the user’s position and orientation. One major issue that makes Computer Vision problems computationally expensive is the high amount of data that has to be processed in real-time. Therefore, one major target for the implementation was to get a processing speed of more than 30 frames per second. This would allow the system to realize feedback to the user in a response time which is faster than the human visual perception. One problem that comes with the idea of using a light emitting device to represent the user, is the precision error. Dependent on the resolution of the tracked projection surface of the immersive environment, a pixel might have a size in cm2. Having a precision error of only a few pixels, might lead to an offset in the estimated user’s position of several cm. In this research work the development and validation of a detection and tracking system for BLOBs on a Cyclone II FPGA from Altera has been realized. The system supports different input devices for the image acquisition and can perform detection and tracking for five to eight BLOBs. A further extension of the design has been evaluated and is possible with some constraints. Additional modules for compressing the image data based on run-length encoding and sub-pixel precision for the computed BLOB center-points have been designed. For the comparison of the FPGA approach for BLOB tracking a similar implementation in software using a multi-threaded approach has been realized. The system can transmit the detection or tracking results on two available communication interfaces, USB and RS232. The analysis of the hardware solution showed a similar precision for the BLOB detection and tracking as the software approach. One problem is the strong increase of the allocated resources when extending the system to process more BLOBs. With one of the applied target platforms, the DE2-70 board from Altera, the BLOB detection could be extended to process up to thirty BLOBs. The implementation of the tracking approach in hardware required much more effort than the software solution. The design of high level problems in hardware for this case are more expensive than the software implementation. The search and match steps in the tracking approach could be realized more efficiently and reliably in software. The additional pre-processing modules for sub-pixel precision and run-length-encoding helped to increase the system’s performance and precision.
Ein SLA (Service Level Agreement) legt alle Punkte einer vertraglichen Zusammenarbeit zwischen Unternehmen und Service Provider verbindlich fest. Ein SLA muss sorgfältig erstellt werden, um ein Vertrauensverhältnis zwischen beiden Seiten herzustellen. Dabei geht es um inhaltliche, organisatorische und technische Anforderungen sowie um eine exakte Festlegung auf verwendete Fachbegriffe und Leistungskriterien. Der vorliegende Beitrag beschreibt Punkt für Punkt den Inhalt eines SLA. Das sind u.a. die Benennung der Vetragspartner, die Leistungskriterien, die die Qualität des Dienstes sicherstellen sowie die Überwachung der Erbringung der vereinbarten Leistung und die Dauer des Vertrages.
At present, data publication is one of the most dynamic topics in e-Research. While the fundamental problems of electronic text publication have been solved in the past decade, standards for the external and internal organisation of data repositories are advanced in some research disciplines but underdeveloped in others. We discuss the differences between an electronic text publication and a data publication and the challenges that result from these differences for the data publication process. We place the data publication process in the context of the human knowledge spiral and discuss key factors for the successful acquisition of research data from the point of view of a data repository. For the relevant activities of the publication process, we list some of the measures and best practices of successful data repositories.
A system that interacts with its environment can be much more robust if it is able to reason about the faults that occur in its environment, despite perfect functioning of its internal components. For robots, which interact with the same environment as human beings, this robustness can be obtained by incorporating human-like reasoning abilities in them. In this work we use naive physics to enable reasoning about external faults in robots. We propose an approach for diagnosing external faults that uses qualitative reasoning on naive physics concepts for diagnosis. These concepts are mainly individual properties of objects that define their state qualitatively. The reasoning process uses physical laws to generate possible states of the concerned object(s), which could result into a detected external fault. Since effective reasoning about any external fault requires the information of relevant properties and physical laws, we associate different properties and laws to different types of faults which can be detected by a robot. The underlying ontology of this association is proposed on the basis of studies conducted (by other researchers) on reasoning of physics novices about everyday physical phenomena. We also formalize some definitions of properties of objects into a small framework represented in First-Order logic. These definitions represent naive concepts behind the properties and are intended to be independent from objects and circumstances. The definitions in the framework illustrates our proposal of using different biased definitions of properties for different types of faults. In this work, we also present a brief review of important contributions in the area of naive/qualitative physics. These reviews help in understanding the limitations of naive/qualitative physics in general. We also apply our approach to simple scenarios to asses its limitations in particular. Since this work was done independent of any particular real robotic system, it can be seen as a theoretical proof of the concept of usefulness of naive physics for external fault reasoning in robotics.
Die Fachhochschulen haben sich als Hochschulen für angewandte Wissenschaften seit ihrer Gründung Anfang der 70er Jahre deutlich gewandelt. Das Fächerportfolio vieler Fachhochschulen ist inzwischen mit jenem der Universitäten vergleichbar. In einigen Fächern bilden die Fachhochschulen sogar den überwiegenden Anteil von Absolventen aus. Die anwendungsorientierte Spitzenforschung gehört zum Selbstverständnis vieler Fachhochschulen. Vor diesem Hintergrund ist es unverständlich und für die wirtschaftliche Zukunftsfähigkeit schädlich, dass Fachhochschulen immer noch deutliche Wettbewerbsnachteile in der Weiterqualifizierung des wissenschaftlichen Nachwuchses haben. Dies gilt umso mehr, wenn mit Fachhochschulen vergleichbaren privaten Hochschulen das Promotionsrecht zugestanden wird.
In dieser Arbeit wird eine Methode zur Darstellung und Generierung von natürlich wirkendem Bewuchs auf besonders großen Arealen und unter Berücksichtigung ökologischer Faktoren vorgestellt. Die Generierung und Visualisierung von Bewuchs ist aufgrund der Komplexität biologischer Systeme und des Detailreichtums von Pflanzenmodellen ein herausforderndes Gebiet der Computergrafik und ermöglicht es, den Realismus von Landschaftsvisualisierungen erheblich zu steigern. Aufbauend auf [DMS06] wird bei Silva der Bewuchs so generiert, dass die zur Darstellung benötigten Wang-Kacheln und die mit ihnen assoziierten Teilverteilungen wiederverwendet werden können. Dazu wird ein Verfahren vorgestellt, um Poisson Disk Verteilungen mit variablen Radien auf nahtlosen Wang-Kachelmengen ohne rechenintensive globale Optimierung zu erzeugen. Durch die Einbeziehung von Nachbarschaften und frei konfigurierbaren Generierungspipelines können beliebige abiotische und biotische Faktoren bei der Bewuchsgenerierung berücksichtigt werden. Die durch Silva auf Wang-Kacheln erzeugten Pflanzenverteilungen ermöglichen, die darauf aufgebauten beschleunigenden Datenstrukturen bei der Visualisierung wieder zu verwenden. Durch Multi-Level Instancing und eine Schachtelung von Kd-Bäumen ist eine Visualisierung von großen bewachsenen Arealen mit geringen Renderzeiten und geringem Memoryfootprint von Hunderten Quadratkilometern Größe möglich.
We present the extensible post processing framework GrIP, usable for experimenting with screen space-based graphics algorithms in arbitrary applications. The user can easily implement new ideas as well as add known operators as components to existing ones. Through a well-defined interface, operators are realized as plugins that are loaded at run-time. Operators can be combined by defining a post processing graph (PPG) using a specific XML-format where nodes are the operators and edges define their dependencies. User-modifiable parameters can be manipulated through an automatically generated GUI. In this paper we describe our approach, show some example effects and give performance numbers for some of them.
We present a graph-based framework for post processing filters, called GrIP, providing the possibility of arranging and connecting compatible filters in a directed, acyclic graph for realtime image manipulation. This means that the construction of whole filter graphs is possible through an external interface, avoiding the necessity of a recompilation cycle after changes in post processing. Filter graphs are implemented as XML files containing a collection of filter nodes with their parameters as well as linkage (dependency) information. Implemented methods include (but are not restricted to) depth of field, depth darkening and an implementation of screen space shadows, all applicable in real-time, with manipulable parameterizations.
In the past decade computer models have become very popular in the field of biomechanics due to exponentially increasing computer power. Biomechanical computer models can roughly be subdivided into two groups: multi-body models and numerical models. The theoretical aspects of both modelling strategies will be introduced. However, the focus of this chapter lies on demonstrating the power and versatility of computer models in the field of biomechanics by presenting sophisticated finite element models of human body parts. Special attention is paid to explain the setup of individual models using medical scan data. In order to reach the goal of individualising the model a chain of tools including medical imaging, image acquisition and processing, mesh generation, material modelling and finite element simulation –possibly on parallel computer architectures- becomes necessary. The basic concepts of these tools are described and application results are presented. The chapter ends with a short outlook into the future of computer biomechanics.