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RNA is one of the most important molecules in living organisms. One of its main functions is to regulate gene expression. This involves binding to and forming a joint structure with a messenger RNA. An RNAs functions is determined by its sequence and the structure it folds into. Accordingly, the prediction of individual as well as joint structures is an important area of research. In this thesis a method for the prediction of RNA-RNA joint structure using their minimum free energy (mfe) structures was developed. It is able to extensively explore the joint structural landscape of two interacting RNAs by taking advantage of the locality of changes in the RNAs structures as well as natural and energetic constraints. The method predicts the mfe joint structure as well as alternative stable joint structures while also computing non-optimal folding pathways from the unbound individual mfe structures to the predicted joint structures. It is shown how an enumeration approach is used which is able to deal with the enormous search space as well as to avoid any cyclic behaviour. The method is evaluated using two standard datasets of known interacting RNAs and shows good results.
Error analysis in a high accuracy sampled-data velocity stabilising system using Volterra series
(2015)
We present GEM-NI -- a graph-based generative-design tool that supports parallel exploration of alternative designs. Producing alternatives is a key feature of creative work, yet it is not strongly supported in most extant tools. GEM-NI enables various forms of exploration with alternatives such as parallel editing, recalling history, branching, merging, comparing, and Cartesian products of and for alternatives. Further, GEM-NI provides a modal graphical user interface and a design gallery, which both allow designers to control and manage their design exploration. We conducted an exploratory user study followed by in-depth one-on-one interviews with moderately and highly skills participants and obtained positive feedback for the system features, showing that GEM-NI supports creative design work well.
Polyether and polyether/ester based TPU (thermoplastic polyurethanes) were investigated with wide-angle XRD (X-ray diffraction) and SAXS (small angle X-ray scattering). Furthermore, SAXS measurements were performed in the temperature range of 30 °C to 130 °C. Polyether based polymers exhibit only one broad diffraction signal in a region of 2 θ 15° to 25°. In case of polyurethanes with ether/ester modification, the broad diffraction signal arises with small sharp diffraction signals. SAXS measurements of polymers reveal the size and shape of the crystalline zones of the polymer. Between 30 °C and 130 °C the size of the crystalline zone changes significantly. The size decreases in most of investigated TPU. In the case of Desmopan 9365D an increase of the particle size was observed.
In der vorliegenden Arbeit wird ein neuartiges Verfahren zur Echtzeitüberwachung von Laserbohrprozessen vorgestellt. Die Untersuchungen werden an unterschiedlichen Materialien unter Einsatz eines passiv-gütegeschalteten Nd:YAG Lasers durchgeführt. Prozessbegleitend findet eine Aufzeichnung der akustischen Emissionen mit anschließender Analyse durch schnelle Fourier-Transformation statt. Hierdurch lassen sich der Durchbruch beim Bohren durch ein Material sowie der Materialübergang mehrschichtiger Systeme detektieren. Die akustischen Messungen werden durchAuswertung der Pulsfolge des Lasers mittels einer Fotodiode gestützt. Hierbei zeigt sich eine gute Übereinstimmung der im akustischen Spektrum dominanten Frequenz mit der jeweils im Laserburstauftretenden Pulsfrequenz. Das vorgestellte Verfahren ermöglicht eine Echtzeitüberwachung beim Laserbohren mittels kostengünstiger und einfacher Hardware. Zudem zeichnet es sich im Gegensatz zu bestehenden Verfahren durch eine hohe Robustheit gegen äußere Störeinflüsse aus, da eine frequenzbasierte Auswertung stattfindet.
Familienunternehmen tragen maßgeblich zur Bruttowertschöpfung der Bundesrepublik Deutschland bei: der Anteil von Familienunternehmen an allen Unternehmen der deutschen Volkswirtschaft am Ende des Jahres 2010 betrug etwa 78 % bei einem Anteil von 56 % an der Gesamtbeschäftigung. Bei allen Familienunternehmen kommt es früher oder später zu einem Wechsel der Leitung und des Eigentums. Die Unternehmensnachfolge ist unvermeidlicher Bestandteil des Lebenszyklus eines Familienunternehmens. Im Zeitraum von 2014 bis 2018 werden pro Jahr etwa 27.000 Nachfolgen in deutschen Familienunternehmen prognostiziert: dies bedeutet rein mathematisch im Durchschnitt etwa eine Nachfolge alle zwanzig Minuten.
We present a system that combines voxel and polygonal representations into a single octree acceleration structure that can be used for ray tracing. Voxels are well-suited to create good level-of-detail for high-frequency models where polygonal simplifications usually fail due to the complex structure of the model. However, polygonal descriptions provide the higher visual fidelity. In addition, voxel representations often oversample the geometric domain especially for large triangles, whereas a few polygons can be tested for intersection more quickly.
Grundlagen des Marketings
(2015)
Detection of triacetone triperoxide using temperature cycled metal-oxide semiconductor gas sensors
(2015)
Virtual reality environments are increasingly being used to encourage individuals to exercise more regularly, including as part of treatment in those with mental health or neurological disorders. The success of virtual environments likely depends on whether a sense of presence can be established, where participants become fully immersed in the virtual environment. Exposure to virtual environments is associated with physiological responses, including cortical activation changes. Whether the addition of a real exercise within a virtual environment alters sense of presence perception, or the accompanying physiological changes, is not known. In a randomized and controlled study design, trials of moderate-intensity exercise (i.e. self-paced cycling) and no-exercise (i.e. automatic propulsion) were performed within three levels of virtual environment exposure. Each trial was 5-min in duration and was followed by post-trial assessments of heart rate, perceived sense of presence, EEG, and mental state. Changes in psychological strain and physical state were generally mirrored by neural activation patterns. Furthermore these change indicated that exercise augments the demands of virtual environment exposures and this likely contributed to an enhanced sense of presence.
Semantic Image Segmentation Combining Visible and Near-Infrared Channels with Depth Information
(2015)
Image understanding is a vital task in computer vision that has many applications in areas such as robotics, surveillance and the automobile industry. An important precondition for image understanding is semantic image segmentation, i.e. the correct labeling of every image pixel with its corresponding object name or class. This thesis proposes a machine learning approach for semantic image segmentation that uses images from a multi-modal camera rig. It demonstrates that semantic segmentation can be improved by combining different image types as inputs to a convolutional neural network (CNN), when compared to a single-image approach. In this work a multi-channel near-infrared (NIR) image, an RGB image and a depth map are used. The detection of people is further improved by using a skin image that indicates the presence of human skin in the scene and is computed based on NIR information. It is also shown that segmentation accuracy can be enhanced by using a class voting method based on a superpixel pre-segmentation. Models are trained for 10-class, 3-class and binary classification tasks using an original dataset. Compared to the NIR-only approach, average class accuracy is increased by 7% for 10-class, and by 22% for 3-class classification, reaching a total of 48% and 70% accuracy, respectively. The binary classification task, which focuses on the detection of people, achieves a classification accuracy of 95% and true positive rate of 66%. The report at hand describes the proposed approach and the encountered challenges and shows that a CNN can successfully learn and combine features from multi-modal image sets and use them to predict scene labeling.
This paper proposes a new artificial neural network-based maximum power point tracker for photovoltaic application. This tracker significantly improves efficiency of the photovoltaic system with series-connection of photovoltaic modules in non-uniform irradiance on photovoltaic array surfaces. The artificial neural network uses irradiance and temperature sensors to generate the maximum power point reference voltage and employ a classical perturb and observe searching algorithm. The structure of the artificial neural network was obtained by numerical modelling using Matlab/Simulink. The artificial neural network was trained using Bayesian regularisation back-propagation algorithms and demonstrated a good prediction of the maximum power point. Relative number of Vmpp prediction errors in range of ±0.2V is 0.05% based on validation data.
IT-accessiblity is often treated as an orphan in companies. Even though the proportion of disabled people is substantial and people become older and more susceptible to disabilities. Besides cost factors, companies often do not have a plan how to implement and control IT-accessibility successfully. However, most companies are familiar with IT-maturity frameworks to evaluate and improve their own IT-infrastructure. It would facilitate dealing with IT-accessibility, if IT-maturity frameworks consider IT-accessibility and provide recommendations and solutions for a successful implementation. Therefore, this article conducts a review of an acknowledged IT-maturity framework with regard to its capability to enable implementation of IT-accessibility in an organization. The first part of this article will illustrate the motivation and background for the authors concern with such a topic. Afterwards the authors will introduce the reader to the reviewed IT-maturity framework and provide basic knowledge on IT-accessibility. The main part of the article will deal with the review of the applied IT-maturity framework and outline examples of critical capabilities for successfully implementing IT-accessibility in an organization. The final section will derive implications and close with planned future research activities in this field.
Advanced driver assistance systems (ADAS) are technology systems and devices designed as an aid to the driver of a vehicle. One of the critical components of any ADAS is the traffic sign recognition module. For this module to achieve real-time performance, some preprocessing of input images must be done, which consists of a traffic sign detection (TSD) algorithm to reduce the possible hypothesis space. Performance of TSD algorithm is critical.
One of the best algorithms used for TSD is the Radial Symmetry Detector (RSD), which can detect both Circular [7] and Polygonal traffic signs [5]. This algorithm runs in real-time on high end personal computers, but computational performance of must be improved in order to be able to run in real-time in embedded computer platforms.
To improve the computational performance of the RSD, we propose a multiscale approach and the removal of a gaussian smoothing filter used in this algorithm. We evaluate the performance on both computation times, detection and false positive rates on a synthetic image dataset and on the german traffic sign detection benchmark [29].
We observed significant speedups compared to the original algorithm. Our Improved Radial Symmetry Detector is up to 5.8 times faster than the original on detecting Circles, up to 3.8 times faster on Triangle detection, 2.9 times faster on Square detection and 2.4 times faster on Octagon detection. All of this measurements were observed with better detection and false positive rates than the original RSD.
When evaluated on the GTSDB, we observed smaller speedups, in the range of 1.6 to 2.3 times faster for Circle and Regular Polygon detection, but for Circle detection we observed a decreased detection rate than the original algorithm, while for Regular Polygon detection we always observed better detection rates. False positive rates were high, in the range of 80% to 90%.
We conclude that our Improved Radial Symmetry Detector is a significant improvement of the Radial Symmetry Detector, both for Circle and Regular polygon detection. We expect that our improved algorithm will lead the way to obtain real-time traffic sign detection and recognition in embedded computer platforms.
Extraction of text information from visual sources is an important component of many modern applications, for example, extracting the text from traffic signs on a road scene in an autonomous vehicle. For natural images or road scenes this is a unsolved problem. In this thesis the use of histogram of stroke widths (HSW) for character and noncharacter region classification is presented. Stroke widths are extracted using two methods. One is based on the Stroke Width Transform and another based on run lengths. The HSW is combined with two simple region features– aspect and occupancy ratios– and then a linear SVM is used as classifier. One advantage of our method over the state of the art is that it is script-independent and can also be used to verify detected text regions with the purpose of reducing false positives. Our experiments on generated datasets of Latin, CJK, Hiragana and Katakana characters show that the HSW is able to correctly classify at least 90% of the character regions, a similar figure is obtained for non-character regions. This performance is also obtained when training the HSW with one script and testing with a different one, and even when characters are rotated. On the English and Kannada portions of the Chars74K dataset we obtained over 95% correctly classified character regions. The use of raycasting for text line grouping is also proposed. By combining it with our HSW-based character classifier, a text detector based on Maximally Stable Extremal Regions (MSER) was implemented. The text detector was evaluated on our own dataset of road scenes from the German Autobahn, where 65% precision, 72% recall with a f-score of 69% was obtained. Using the HSW as a text verifier increases precision while slightly reducing recall. Our HSW feature allows the building of a script-independent and low parameter count classifier for character and non-character regions.
Permanenz in Inkohärenz
(2015)
Secure vehicular communication has been discussed over a long period of time. Now,- this technology is implemented in different Intelligent Transportation System (ITS) projects in europe. In most of these projects a suitable Public Key Infrastructure (PKI) for a secure communication between involved entities in a Vehicular Ad hoc Network (VANET) is needed. A first proposal for a PKI architecture for Intelligent Vehicular Systems (IVS PKI) is given by the car2car communication consortium. This architecture however mainly deals with inter vehicular communication and is less focused on the needs of Road Side Units. Here, we propose a multi-domain PKI architecture for Intelligent Transportation Systems, which considers the necessities of road infrastructure authorities and vehicle manufacturers, today. The PKI domains are cryptographically linked based on local trust lists. In addition, a crypto agility concept is suggested, which takes adaptation of key length and cryptographic algorithms during PKI operation into account.
The latest advances in the field of smart card technologies allow modern cards to be more than just simple security tokens. Recent developments facilitate the use of interactive components like buttons, displays or even touch-sensors within the card's body thus conquering whole new areas of application. With interactive functionalities the usability aspect becomes the most important one for designing secure and popularly accepted products. Unfortunately, the usability can only be tested fully with completely integrated hence expensive smart card prototypes. This restricts severely application specific research, case studies of new smart card user interfaces and the optimization of design aspects, as well as hardware requirements by making usability and acceptance tests in smart card development very costly and time-consuming. Rapid development and simulation of smart card interfaces and applications can help to avoid this restriction. This paper presents a rapid development process for new smart card interfaces and applications based on common smartphone technology using a tool called SCUID^Sim. We will demonstrate the variety of usability aspects that can be analyzed with such a simulator by discussing some selected example projects.
This paper proposes an Artificial Plasmodium Algorithm (APA) mimicked a contraction wave of a plasmodium of physarum polucephalum. Plasmodia can live using the contracion wave in their body to communicate to others and transport a nutriments. In the APA, each plasmodium has two information as the wave information: the direction and food index. We apply the APA to 4 types of mazes and confirm that the APA can solve the mazes.