Refine
Departments, institutes and facilities
- Fachbereich Informatik (58)
- Fachbereich Wirtschaftswissenschaften (44)
- Institut für funktionale Gen-Analytik (IFGA) (33)
- Präsidium (29)
- Fachbereich Angewandte Naturwissenschaften (27)
- Institute of Visual Computing (IVC) (18)
- Fachbereich Ingenieurwissenschaften und Kommunikation (13)
- Institut für Cyber Security & Privacy (ICSP) (13)
- Fachbereich Sozialpolitik und Soziale Sicherung (6)
- Institut für Verbraucherinformatik (IVI) (6)
Document Type
- Article (107)
- Conference Object (64)
- Part of a Book (47)
- Part of Periodical (29)
- Book (monograph, edited volume) (21)
- Report (7)
- Lecture (5)
- Master's Thesis (5)
- Doctoral Thesis (4)
- Contribution to a Periodical (3)
- Bachelor Thesis (2)
- Patent (2)
- Conference Proceedings (1)
- Diploma Thesis (1)
- Other (1)
- Study Thesis (1)
- Working Paper (1)
Year of publication
- 2012 (301) (remove)
Keywords
- Wirtschaftsethik (7)
- Corporate Social Responsibility (5)
- Macht (5)
- Unternehmensethik (5)
- Ethik (4)
- ENaC (3)
- ISM: molecules (3)
- Lehrbuch (3)
- Management (3)
- Vertrauen (3)
This article concerns with the accessibility of Business process modelling tools (BPMo tools) and business process modelling languages (BPMo languages). Therefore the reader will be introduced to business process management and the authors' motivation behind this inquiry. Afterwards, the paper will reflect problems when applying inaccessible BPMo tools. To illustrate these problems the authors distinguish between two different categories of issues and provide practical examples. Finally the article will present three approaches to improve the accessibility of BPMo tools and BPMo languages.
This article concerns the design and development of Information- and Communication Technology, in particular computer systems in regard to the demographic transition which will influence user capabilities. It is questionable if current applied computer systems are able to meet the requirements of altered user groups with diversified capabilities. Such an enquiry is necessary based on actual forecasts leading to the assumption that the average age of employees in enterprises will increase significantly within the next 50-60 years, while the percentage of computer aided business tasks, operated by human individuals, rises from year to year. This progress will precipitate specific consequences for enterprises regarding the design and application of computer systems. If computer systems are not adapted to altered user requirements, efficient and productive utilisation could be negatively influenced. These consequences constitute the motivation to extend traditional design methodologies and thereby ensure the application of computer systems that are usable, independent of user capabilities.
Wesch D, Althaus M, Miranda P, Cruz-Muros I, Fronius M, Gonzalez-Hernandez T, Clauss WG, de la Rosa DA, Giraldez T. Differential N termini in epithelial Na+ channel delta-subunit isoforms modulate channel trafficking to the membrane. Am J Physiol Cell Physiol 302: C868-C879, 2012. First published December 7, 2011; doi: 10.1152/ajpcell.00255.2011.-The epithelial Na+ channel (ENaC) is a heteromultimeric ion channel that plays a key role in Na+ reabsorption across tight epithelia. The canonical ENaC is formed by three analogous subunits, alpha, beta, and gamma. A fourth ENaC subunit, named delta, is expressed in the nervous system of primates, where its role is unknown. The human delta-ENaC gene generates at least two splice isoforms, delta(1) and delta(2), differing in the N-terminal sequence. Neurons in diverse areas of the human and monkey brain differentially express either delta(1) or delta(2), with few cells coexpressing both isoforms, which suggests that they may play specific physiological roles. Here we show that heterologous expression of delta(1) in Xenopus oocytes and HEK293 cells produces higher current levels than delta(2). Patch-clamp experiments showed no differences in single channel current magnitude and open probability between isoforms. Steady-state plasma membrane abundance accounts for the dissimilarity in macroscopic current levels. Differential trafficking between isoforms is independent of beta- and gamma-subunits, PY-motif-mediated endocytosis, or the presence of additional lysine residues in delta(2)-N terminus. Analysis of delta(2)-N terminus identified two sequences that independently reduce channel abundance in the plasma membrane. The delta(1) higher abundance is consistent with an increased insertion rate into the membrane, since endocytosis rates of both isoforms are indistinguishable. Finally, we conclude that delta-ENaC undergoes dynamin-independent endocytosis as opposed to alpha beta gamma-channels.
Nützt oder schadet ethisches Verhalten der Karriere und dem Erfolg der Mitarbeiter und ihrer Unternehmen? Wenn man gerade die letzten 10 Entwicklungsjahre in vielen Unternehmen sieht, könnte man spontan die Meinung vertreten, dass Ethik und Moral der Karriere eher schadet, legt man den Maßstab an moralische Qualitäten des täglichen Handelns.
Human mesenchymal stem cells (hMSCs) are considered a promising cell source for regenerative medicine, because they have the potential to differentiate into a variety of lineages among which the mesoderm-derived lineages such adipo- or osteogenesis are investigated best. Human MSCs can be harvested in reasonable to large amounts from several parts of the patient’s body and due to this possible autologous origin, allorecognition can be avoided. In addition, even in allogenic origin-derived donor cells, hMSCs generate a local immunosuppressive microenvironment, causing only a weak immune reaction. There is an increasing need for bone replacement in patients from all ages, due to a variety of reasons such as a new recreational behavior in young adults or age-related diseases. Adipogenic differentiation is another interesting lineage, because fat tissue is considered to be a major factor triggering atherosclerosis that ultimately leads to cardiovascular diseases, the main cause of death in industrialized countries. However, understanding the differentiation process in detail is obligatory to achieve a tight control of the process for future clinical applications to avoid undesired side effects. In this review, the current findings for adipo- and osteo-differentiation are summarized together with a brief statement on first clinical trials.
Transient up-regulation of P2 receptors influence differentiation of human mesenchymal stem cells
(2012)
Interactive Distributed Rendering of 3D Scenes on Multiple Xbox 360 Systems and Personal Computers
(2012)
Topics
Dialogue University President Hartmut Ihne and Jakob Rhyner, Vice Rector of the United Nations University (UNU), talk about common goals and the concept of regional internationality ...
Studies and Teaching University scores high with the Teaching Quality Pact (Pro-MINT-us), career training and Bachelor studies all in one, three attractive Master’s programmes set up, central e-Learning platform online, International Centre for Sustainable Development already hard at work ...
Research Graduate Institute establishes new Ph.D. culture, research focus on visual computing secures third-party funding, energy harvesting project wins university competition, research on the impact of zero gravity on arteries, security systems protect against car thieves ...
Campus Centre for Science and Technology Transfer, International Welcome Centre - a first stop for foreign students, alumni coordinator keeps in close contact with former students, hackathon brings students from around the world together, H-BRS prepared for the double Abitur year ...
What if ... ... the Bonn-Rhein-Sieg University of Applied Sciences did not exist? Personal answers to an unusual question ...
Region H-BRS- a strong engine for the region, research centre for region’s SMEs looks for investors, companies invest in scholarships, students advise the Alexander- Koenig-Gesellschaft, BusinessCampus opens a third location, concept for medical tourism along the Rhine corridor ...
International Mechanical engineering students in Ethiopia, businesses and universities collaborate in Ghana, university partnership with Namibia, Study Buddies for foreign students, student initiates German-Argentine Master’s degree, Spanish teacher conference, intercultural training for all university staff ...
Facts and Figures Programmes of study, statistics, organisational structure, international partnerships, awards ...
This book constitutes the thoroughly refereed post-conference proceedings of the Third International ICST Conference on e-Infrastructure and e-Services for Developing Countries, AFRICOMM 2011, held in Zanzibar, Tansania, in November 2011. The 24 revised full papers presented together with 2 poster papers were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in the field of information and communication infrastructures. They are organized in two tracks: communication infrastructures for developing countries and electronic services, ICT policy, and regulatory issues for developing countries.
Werte gelten gemeinhin als Orientierungsgrundlagen von Individuen und Gesellschaften. Führungskräfte sind für die Praxis sozialer Verantwortung wirtschaftlicher, politischer und sozialer Organisationen von herausragender Bedeutung.
Ziel des vorliegenden Bandes ist es, das Thema Werte und Werthaltungen von angehenden Führungskräften aus interdisziplinärer wissenschaftlicher sowie aus wirtschafts- und gesellschaftsbezogener Perspektive zu beleuchten. Die zentralen Themen dabei sind die Bestandsaufnahme und Erfassung von Werten und Werthaltungen, die Anforderungen an die Werthaltungen von Führungskräften aus Wirtschaft und Gesellschaft sowie die Vermittlung von Werten an die künftigen Führungskräfte. Die Thematik wird von ausgewiesenen Experten aus Wissenschaft und Praxis facettenreich behandelt und präsentiert. So werden in diesem Sammelband aktuelle und zukunftsweisende wirtschaftsethische Themen einer vielfältigen Analyse unterzogen und Antworten auf brennende Fragen gegeben.
Macht in Unternehmen
(2012)
Kaum ein Begriff ist so diskreditiert wie der der Macht. Sie wird mit Missbrauch, Willkür und Irrationalität verbunden, allein das Streben danach gilt als verdächtig. Dabei ist die regulierende und gestaltende Funktion der Macht für und in Organisationen aus dem Blick geraten, aber auch die Frage nach den Ursprüngen und den Regulativen von Macht. Das Buch untersucht diese Thematik aus der Perspektive von Wissenschaftlern verschiedener Disziplinen und von "Praktikern der Macht" aus Unternehmen und Politik.