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ICT has traditionally been a hostile territory for women. In information societies, this implies a drastic reduction in opportunities and autonomy for women. In emergent economies, the situation is even worse due to women’s subordinate status in society and little research regarding the intersection between gender and the digital divide. Such is the case in Latin America. In light of this, the purpose of this essay is to introduce a first comprehensive review of the few studies made in Latin America, against the background of the history of women’s digital exclusion. Based on a review of literature, we identify the main causes for women’s digital exclusion in the region and talk about the prospects for development of gender policies in the BRICS countries (Brazil, Russia, India, China and South Africa). We conclude that what this group of countries may achieve in regard to gender equality, will mark the future of the world. The aim of this essay is to make a call for the creation of inter - national research networks and propose the BRICS as host for these efforts, as they combine characteristics that will make them leaders of change in vast regions.
The design of an efficient digital circuit in term of low-power has become a very challenging issue. For this reason, low-power digital circuit design is a topic addressed in electrical and computer engineering curricula, but it also requires practical experiments in a laboratory. This PhD research investigates a novel approach, the low-power design laboratory system by developing a new technical and pedagogical system. The low-power design laboratory system is composed of two types of laboratories: the on-site (hands-on) laboratory and the remote laboratory. It has been developed at the Bonn-Rhine-Sieg University of Applied Sciences to teach low-power techniques in the laboratory. Additionally, this thesis contributes a suggestion on how the learning objectives can be complemented by developing a remote system in order to improve the teaching process of the low-power digital circuit design. This laboratory system enables online experiments that can be performed using physical instruments and obtaining real data via the internet. The laboratory experiments use a Field Programmable Gate Array (FPGA) as a design platform for circuit implementation by students and use image processing as an application for teaching low-power techniques.
This thesis presents the instructions for the low-power design experiments which use a top-down hierarchical design methodology. The engineering student designs his/her algorithm with a high level of abstraction and the experimental results are obtained and measured at a low level (hardware) so that more information is available to correctly estimate the power dissipation such as specification, latency, thermal effect, and technology used. Power dissipation of the digital system is influenced by specification, design, technology used, as well as operating temperature. Digital circuit designers can observe the most influential factors in power dissipation during the laboratory exercises in the on-site system and then use the remote system to supplement investigating the other factors. Furthermore, the remote system has obvious benefits such as developing learning outcomes, facilitating new teaching methods, reducing costs and maintenance, cost-saving by reducing the numbers of instructors, saving instructor time and simplifying their tasks, facilitating equipment sharing, improving reliability, and finally providing flexibility of usage the laboratories.
Umwelt: Technologien, um die Folgen des Klimawandels zu begrenzen, gibt es. Die soziale und politische Dimension ist der Hemmschuh, so dass sie teils nur zögernd zum Einsatz kommen.
Die Redaktion der VDI nachrichten betreute drei Studierende, die aktuell von jedem Vortrag einen Artikel für unser Ingenieurportal www.ingenieur.de schrieben sowie eine Meldung für die VDI-nachrichten-E-Paper-App. Dieser Artikel ist das Resümee der drei zur Ringvorlesung, aber keine inhaltlich komplette Zusammenfassung. Alle Artikel lesen Sie online unter: www.ingenieur.de/Ringvorlesung2018
Technische Innovationen verändern den Alltag enorm – auch den von Journalisten. Technik-Fachjournalisten sind daher gefragt wie nie. Was sie können müssen, wie in den Medien über Digitalisierung berichtet wird und inwiefern künstliche Intelligenz (KI) Journalisten in Zukunft überflüssig machen wird, beantwortet der Medienwissenschaftler Andreas Schümchen im Gespräch mit dem "Fachjournalist".
Mehr machen, weniger planen!
(2018)
Differential-Algebraic Equations and Beyond: From Smooth to Nonsmooth Constrained Dynamical Systems
(2018)
The present article presents a summarizing view at differential-algebraic equations (DAEs) and analyzes how new application fields and corresponding mathematical models lead to innovations both in theory and in numerical analysis for this problem class. Recent numerical methods for nonsmooth dynamical systems subject to unilateral contact and friction illustrate the topicality of this development.
Preleukemic clones carrying BCR-ABLp190 oncogenic lesions are found in neonatal cord blood, where the majority of preleukemic carriers do not convert into precursor B-cell acute lymphoblastic leukemia (pB-ALL). However, the critical question of how these preleukemic cells transform into pB-ALL remains undefined. Here we model a BCR-ABLp190 preleukemic state and show that limiting BCR-ABLp190 expression to hematopoietic stem/progenitor cells (HS/PC) in mice (Sca1-BCR-ABLp190) causes pB-ALL at low penetrance, which resembles the human disease. pB-ALL blast cells were BCR-ABL-negative and transcriptionally similar to pro-B/pre-B cells, suggesting disease onset upon reduced Pax5 functionality. Consistent with this, double Sca1-BCR-ABLp190+Pax5+/- mice developed pB-ALL with shorter latencies, 90% incidence, and accumulation of genomic alterations in the remaining wild-type Pax5 allele. Mechanistically, the Pax5-deficient leukemic pro-B cells exhibited a metabolic switch towards increased glucose utilization and energy metabolism. Transcriptome analysis revealed that metabolic genes (IDH1, G6PC3, GAPDH, PGK1, MYC, ENO1, ACO1) were upregulated in Pax5-deficient leukemic cells, and a similar metabolic signature could be observed in human leukemia. Our studies unveil the first in vivo evidence that the combination between Sca1-BCR-ABLp190 and metabolic reprogramming imposed by reduced Pax5 expression is sufficient for pB-ALL development. These findings might help to prevent conversion of BCR-ABLp190 preleukemic cells.
For the last 20 years, solid-phase microextraction (SPME) in headspace (HS) mode has been used as a valuable sample preparation technique for identifying degradation products in polymers and the determination of residual monomers and other light-boiling substances in polymeric materials. For more than 10 years, our laboratory has been involved in projects focused on the application of HS-SPME-gas chromatography–mass spectrometry (GC–MS) for the characterization of polymeric materials from many branches of manufacturing and building industries. This article describes the application of this technique for identifying volatile organic compounds (VOCs), additives, and degradation products in industrial rubber, car labeling reflection foil, and bone cement materials. The obtained analytical results were then used for troubleshooting and remedial action of the technological processes as well as for the health protection of producers and users.