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These times are very troubled ones. Not only do wars and political unrest seem to prevail in different regions of the world, but, corruption and fraud have reached an incredible dimension, too. It seems that societies have, to a large extent, lost values in which they had formerly believed in. These issues may be the background why at the moment Corporate Social Responsibility (CSR) as a voluntary commitment is discussed in public that intensively. However, one gets the impression that this rather often seems to be superficial. Therefore, it is time to do some in-depth research to identify whether there is real substance behind these discussions or not. Latin America is a big continent with a greater number of countries which are running through difficult times as to corruption and fraud. Consequently, the author studied the policy of the central employers association Consejo Empresarial de America Latina (CEAL) with respect to the role of CSR. On the basis of statements, news and results of studies being regularly published, conclusions were drawn to which extent social and environmental aspects, along the line of ISO 26000, are playing a relevant role.
In order to avoid a too narrow view of the issue, a holistic approach concerning the generalsituation of Latin America has been selected using parameters such as economic growth, increase of population, poverty, inequality, and the global responsibility for environment. Furthermore, apart from the central organization CEAL, regional and national institutions with a specific mission for spreading and implementing CSR and two communal projects were analyzed as well. The conclusion of the paper is that there are some CSR "lighthouses" but an urgent need exists to spread the idea of CSR more intensively across the continent. Corresponding recommendations about how to increase the relevance of CSR in Latin America are given at the end of the paper.
The combination of Software-Defined Networking (SDN) and Wireless Mesh Network (WMN) is challenging due to the different natures of both concepts. SDN describes networks with homogeneous, static and centralized controlled topologies. In contrast, a WMN is characterized by a dynamic and distributed network control, and adds new challenges with respect to time-critical operation. However, SDN and WMN are both associated with decreasing the operational costs for communication networks which is especially beneficial for internet provisioning in rural areas. This work surveys the current status for Software-Defined Wireless Mesh Networking. Besides a general overview in the domain of wireless SDN, this work focuses especially on different identified aspects: representing and controlling wireless interfaces, control-plane connection and topology discovery, modulation and coding, routing and load-balancing and client handling. A complete overview of surveyed solutions, open issues and new research directions is provided with regard to each aspect.
In January 2015, German trade and industry announced to support the national animal welfare initiative "Initiative Tierwohl" (ITW) which stands for a more sustainable and animal-friendly meat production. A web content analysis shows that the ITW initiative has been widely picked up and discussed by online media and that user comments are quite heterogeneous. The current study identifies different types of consumers through factor and cluster analysis and is based on an online survey as well as face-to-face interviews. According to our results, the identified consumer groups demonstrate a rather passive comment behaviour on the internet. In fact, the internet was hardly mentioned as an information source for meat production; consumers more frequently referred to brochures, leaflets and personal contacts with sales personnel.
Argentina substantially contributes to the global organic agriculture and food sector due to its large areas of organically managed agricultural land. However, most of the organic production is foreseen for export. Overall, food supply for the domestic organic market is hardly tapped. This study investigates the current importance of organic agriculture and food production as well as its consumption within the country. The novelty of the study also lies in the observation, documentation and analysis of latest stakeholder-driven developments towards organic agriculture and food. The publication allows to make the Argentinian organic market significantly more visible for the international audience.
Food losses occur for many reasons at all stages of supply chains for fruits, vegetables and potatoes. They cause immense economic, environmental and social costs – not only in developing countries but also in developed countries. According to the European Commission, about 90 million tonnes of food are wasted annually in Europe alone. However, particularly for the early stages of supply chains for fruits, vegetables and potatoes there is still a lack of reliable data. Thus, one objective of this study is to contribute to the quantification of food losses between field and retail, where the main focus is set on potatoes, apples, carrots, strawberries and asparagus. Furthermore, neither reasons why products are removed from the supply chains nor their alternative uses are fully examined yet. This is why, the study takes a look on those issues, too. Results are based on data from an online survey among producers of fruits, vegetables and potatoes in North-Rhine Westphalia, Germany and on interviews with producers and other supply chain experts. Findings suggest that the products’ size and form, their storage capabilities and food safety issues have big impacts on food losses. Despite a small sample size, these findings are in line with recent studies.
Infection Exposure Promotes ETV6-RUNX1 Precursor B-cell Leukemia via Impaired H3K4 Demethylases
(2017)
ETV6-RUNX1 is associated with the most common subtype of childhood leukemia. As few ETV6-RUNX1 carriers develop precursor B cell acute lymphocytic leukemia (pB-ALL), the underlying genetic basis for development of full-blown leukemia remains to be identified, but the appearance of leukemia cases in time-space clusters keeps infection as a potential causal factor. Here we present in vivo genetic evidence mechanistically connecting preleukemic ETV6-RUNX1 expression in hematopoetic stem cells/peripheral cells (HSC/PC) and postnatal infections for human-like pB-ALL. In our model, ETV6-RUNX1 conferred a low risk of developing pB-ALL after exposure to common pathogens, corroborating the low incidence observed in humans. Murine preleukemic ETV6-RUNX1 pro/preB cells showed high Rag1/2 expression, known for human ETV6-RUNX1 pB-ALL. Murine and human ETV6-RUNX1 pB-ALL revealed recurrent genomic alterations, with a relevant proportion affecting genes of the lysine demethylase (KDM) family. KDM5C loss-of-function resulted in increased levels of H3K4me3, which co-precipitated with RAG2 in a human cell line model, laying the molecular basis for recombination activity. We conclude that alterations of KDM family members represent a disease-driving mechanism and an explanation for RAG off-target cleavage observed in humans. Our results explain the genetic basis for clonal evolution of an ETV6-RUNX1 preleukemic clone to pB-ALL after infection exposure and offer the possibility of novel therapeutic approaches.
This report presents an approach on a quadrotor dynamics stabilization based on ICP SLAM. Because the quadrotor lacks sensory information to detect its horizontal drift an additional sensor as Hokuyo-UTM has been used to perform on-line ICP-based SLAM. The obtained position estimates were used in control loops to maintain desired position and orientation of the vehicle. Such attitude parameters as height, yaw and position in space were controlled based on the laser data. As a result the quadrotor demonstrated two significant for autonomous navigation capabilities: performance of on-line SLAMon a flying vehicle and maintaining desired position in 3D space. Visual approach on optical flow based on Pyramid Lucas-Kanade algorithm has been touched and tested in different environmental conditions though hasn't been implemented in the control loop. Also the performance of the Hokuyo laser scanner and the related to it ICP SLAM algorithm have been tested in different environmental conditions indoors, outdoors and in presence of smoke. Results are presented and discussed. The requirement of performing on-line SLAM algorithm and to carry quite heavy equipment for it forced to seek a solution to increase the payload of the quadrotor with its computational power. A new hardware and distributed software architectures are therefore presented in the report.
In order to help journalists investigate inside large audiovisual archives, as maintained by news broadcast agencies, the multimedia data must be indexed by text-based search engies. By automatically creating a transcript through automatic speech recognition (ASR), the spoken word becomes accessible to text search, and queries for keywords are made possible. But stil, important contextual information like the identity of the speaker is not captured. Especially when gathering original footage in the political domain, the identity of the speaker can be the most important query constraint, although this name may not be prominent in the words spoken. It is thus desireable to have this information provided explicitely to the search engine. To provide this information, the archive must be an alyzed by automatic Speaker Identification (SID). While this research topic has seen substantial gains in accuracy and robustness over last years, it has not yet established itself as a helpful, large-scale tool outside the research community. This thesis sets out to establish a workflow to provide automatic speaker identification. Its application is to help journalists searching on speeches given in the German parliament (Bundestag). This is a contribution to the News-Stream 3.0 project, a BMBF funded research project that addresses accessibility of various data sources for journalists.