Refine
H-BRS Bibliography
- yes (76) (remove)
Departments, institutes and facilities
- Fachbereich Wirtschaftswissenschaften (22)
- Fachbereich Angewandte Naturwissenschaften (20)
- Fachbereich Ingenieurwissenschaften und Kommunikation (14)
- Fachbereich Informatik (12)
- Institut für funktionale Gen-Analytik (IFGA) (8)
- Fachbereich Sozialpolitik und Soziale Sicherung (7)
- Institut für Technik, Ressourcenschonung und Energieeffizienz (TREE) (3)
- Institut für Sicherheitsforschung (ISF) (2)
- Institut für Verbraucherinformatik (IVI) (2)
- Institute of Visual Computing (IVC) (2)
Document Type
- Article (76) (remove)
Year of publication
- 2013 (76) (remove)
Keywords
- Corporate Social Responsibility (3)
- ionic liquids (2)
- paper-derived ceramic (2)
- preceramic paper (2)
- 3D real-time echocardiography (1)
- Adipogenesis (1)
- Aluminiumoxid (1)
- Analytical pyrolysis (1)
- Ankle Joint (1)
- Articular Cartilage (1)
Hochschulen beschäftigen sich mit der Frage, wie Lehrveranstaltungen und Forschungsprojekte durch den Einsatz digitaler Werkzeuge und Lernplattformen begleitet und ergänzt werden können. Bibliotheken spielen hierbei häufig eine tragende Rolle, auf ganz unterschiedliche Art und Weise: Als Content-Entwickler und -Provider, als Supportstelle oder als E-Learning-Beratungsstelle für Lehrende und Studierende.
Although most individuals who gamble do so without any adverse consequences, some individuals develop a recurrent, maladaptive pattern of gambling behaviour, often called pathological gambling or gambling disorder, that is associated with financial losses, disruption of family and interpersonal relationships, and co-occurring psychiatric disorders. Identifying whether different types of gambling modalities vary in their ability to lead to maladaptive patterns of gambling behaviour is essential to develop public policies that seek to balance access to gambling opportunities with minimizing risk for the potential adverse consequences of gambling behaviour. Until recently, assessing the risk potential of different types of gambling products was nearly impossible. ASTERIG, initially developed in Germany in 2006-2010, is an assessment tool to measure and to evaluate the risk potential of any gambling product based on scores on ten dimensions. In doing so, it also allows a comparison to be drawn between the addictive potential of different gambling products. Furthermore, the tool highlights where the specific risk potential of each specific gambling product lies. This makes it a valuable tool at the legislative, case law, and administrative levels as it allows the risk potential of individual gambling products to be identified and to be compared globally and across 10 different dimensions of risk potential. We note that specific gambling products should always be evaluated rather than product groups (lotteries, slot machines) or providers, as there may be variations among those product groups that impact their risk potential. For example, slot machines may vary on the amount of jackpot, which may influence their risk potential.
Increased endothelin-1 decreases PKC alpha (PKCα), resulting in high miRNA 15a levels in kidney tumors. Breast cancer cells treated with ET-1, β-estrogen, Tamoxifen, Tamoxifen + β-estrogen and Tamoxifen + ET-1 were analysed regarding miRNA 15a expression. Significantly increased miRNA 15a levels were found after ET-1, becoming further increased in Tamoxifen + ET-1 treated cells. Our group already showed that miRNA 15a induces MAPK p38 splicing resulting in a truncated product called Mxi-2, whose function has yet to be defined in tumors. We described for the first time in ET-1 induced tumor cells that Mxi-2 builds a complex with Ago2, a miRNA binding protein, which is important for the localization of miRNAs to the 3′UTR of target genes. Furthermore, we show that Mxi-2/Ago2 is important for the interaction with the miRNA 1285 which binds to the 3′end of the tumor suppressor gene p53, being responsible for the downregulation of p53. Tissue arrays from breast cancer patients were performed, analysing Mxi-2, p53 and PKCα. Since the Mxi-2 levels increase in Tamoxifen + ET-1 treated cells, we claim that increasing ET-1 levels in Tamoxifen treated breast cancer patients are responsible for decreasing p53 levels. In summary, ET-1 decreases nuclear PKCα levels, while increasing the amount of miRNA 15a. This causes high levels of Mxi-2, necessary for complex formation with Ago2. The newly identified Mxi-2/Ago2 complex interacting with miRNA 1285 leads to increased 3′UTR p53 interaction, resulting in decreased p53 levels and subsequent tumor progression. This newly identified mechanism is a possible explanation for the development of ET-1 induced tumors.
Earth’s nearest candidate supermassive black hole lies at the centre of the Milky Way1. Its electromagnetic emission is thought to be powered by radiatively inefficient accretion of gas from its environment2, which is a standard mode of energy supply for most galactic nuclei. X-ray measurements have already resolved a tenuous hot gas component from which the black hole can be fed3. The magnetization of the gas, however, which is a crucial parameter determining the structure of the accretion flow, remains unknown. Strong magnetic fields can influence the dynamics of accretion, remove angular momentum from the infalling gas4, expel matter through relativistic jets5 and lead to synchrotron emission such as that previously observed6, 7, 8. Here we report multi-frequency radio measurements of a newly discovered pulsar close to the Galactic Centre9, 10, 11, 12 and show that the pulsar’s unusually large Faraday rotation (the rotation of the plane of polarization of the emission in the presence of an external magnetic field) indicates that there is a dynamically important magnetic field near the black hole. If this field is accreted down to the event horizon it provides enough magnetic flux to explain the observed emission—from radio to X-ray wavelengths—from the black hole.
Die Klausur
(2013)
Die Aufgaben sind Teil einer Klausur, die im Sommersemester 2013 von Prof. Dr.
Andreas Gadatsch (Hochschule Bonn-Rhein-Sieg) im Prüfungsfach IT-Controlling
für Wirtschaftswissenschaftler des Master-Studiengangs Informations- und
Innovationsmanagement gestellt wurde. Bearbeitungszeit der gesamten Klausur:
90 Minuten.
Unter Big Data wird die Echtzeitverarbeitung sehr großer Datenmengen für analytische Aufgaben verstanden. Neue Technologien und Methoden machen es möglich, bislang nicht genutzte Analyseaufgaben in kürzester Zeit durchzuführen. Der Beitrag zeigt, wie Big Data in den betriebswirtschaftlichen Kontext einzuordnen ist, welche Chancen den Unternehmen offen stehen und welche Auswirkungen dies für den Controller haben wird.
IT-gestütztes IT-Controlling
(2013)
Die Greenpocket GmbH hat in Kooperation mit der Hochschule Bonn-Rhein-Sieg eine Studie zum Thema Smart Home durchgeführt. Wie die Onlinebefragung zeigt, ist die Zahlungsbereitschaft für Smart-Home-Lösungen bei jungen, technikaffinen Verbrauchern, den Digital Natives, höher ls bisher angenommen. Insgesamt umfasste der Online-Fragebogen 32 Fragen. Teile der Befragung wurden nach dem Kano-Modell konzipiert. Zu den Ergebnissen der Befragung: Der Steuerung über das Smartphone kommt eine wichtige Rolle zu. Insgesamt ist die Qualität wichtiger als ein niedriger Preis. Langfristig sollte ein Smart Home die Gewohnheiten des Nutzers automatisch erkennen und berücksichtigen können. Die Anbindung an soziale Netzwerke wird hingegen kritisch beurteilt. Als wünschenswert wird die Steuerung von Haushalts- und Elektrogeräten in Abhängigkeit vom Strompreis empfunden.
Die Vorstandsperspektive
(2013)