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An electronic display often has to present information from several sources. This contribution reports about an approach, in which programmable logic (FPGA) synchronises and combines several graphics inputs. The application area is computer graphics, especially rendering of large 3D models, which is a computing intensive task. Therefore, complex scenes are generated on parallel systems and merged to give the requested output image. So far, the transportation of intermediate results is often done by a local area network. However, as this can be a limiting factor, the new approach removes this bottleneck and combines the graphic signals with an FPGA.
Environment monitoring using multiple observation cameras is increasingly popular. Different techniques exist to visualize the incoming video streams, but only few evaluations are available to find the best suitable one for a given task and context. This article compares three techniques for browsing video feeds from cameras that are located around the user in an unstructured manner. The techniques allow mobile users to gain extra information about the surroundings, the objects and the actors in the environment by observing a site from different perspectives. The techniques relate local and remote cameras topologically, via a tunnel, or via bird's eye viewpoint. Their common goal is to enhance spatial awareness of the viewer, without relying on a model or previous knowledge of the environment. We introduce several factors of spatial awareness inherent to multi-camera systems, and present a comparative evaluation of the proposed techniques with respect to spatial understanding and workload.
In this paper, we report on four generations of display-sensor platforms for handheld augmented reality. The paper is organized as a compendium of requirements that guided the design and construction of each generation of the handheld platforms. The first generation, reported in [17]), was a result of various studies on ergonomics and human factors. Thereafter, each following iteration in the design-production process was guided by experiences and evaluations that resulted in new guidelines for future versions. We describe the evolution of hardware for handheld augmented reality, the requirements and guidelines that motivated its construction.
Dihydropyrimidinase deficiency: Phenotype, genotype and structural consequences in 17 patients
(2010)
Dihydropyrimidine Dehydrogenase Deficiency Caused by a Novel Genomic Deletion c.505_513del of DPYD
(2010)
Low Cost Displays
(2010)
Simultaneous detection of cyanide and heavy metals for environmental analysis by means of µISEs
(2010)
BACKGROUND
Activator protein-2 (AP-2) transcription factors are critically involved in a variety of fundamental cellular processes such as proliferation, differentiation and apoptosis and have also been implicated in carcinogenesis. Expression of the family members AP-2alpha and AP-2gamma is particularly well documented in malignancies of the female breast. Despite increasing evaluation of single AP-2 isoforms in mammary tumors the functional role of concerted expression of multiple AP-2 isoforms in breast cancer remains to be elucidated. AP-2 proteins can form homo- or heterodimers, and there is growing evidence that the net effect whether a cell will proliferate, undergo apoptosis or differentiate is partly dependent on the balance between different AP-2 isoforms.
METHODS
We simultaneously interfered with all AP-2 isoforms expressed in ErbB-2-positive murine N202.1A breast cancer cells by conditionally over-expressing a dominant-negative AP-2 mutant.
RESULTS
We show that interference with AP-2 protein function lead to reduced cell number, induced apoptosis and increased chemo- and radiation-sensitivity. Analysis of global gene expression changes upon interference with AP-2 proteins identified 139 modulated genes (90 up-regulated, 49 down-regulated) compared with control cells. Gene Ontology (GO) investigations for these genes revealed Cell Death and Cell Adhesion and Migration as the main functional categories including 25 and 12 genes, respectively. By using information obtained from Ingenuity Pathway Analysis Systems we were able to present proven or potential connections between AP-2 regulated genes involved in cell death and response to chemo- and radiation therapy, (i.e. Ctgf, Nrp1, Tnfaip3, Gsta3) and AP-2 and other main apoptosis players and to create a unique network.
CONCLUSIONS
Expression of AP-2 transcription factors in breast cancer cells supports proliferation and contributes to chemo- and radiation-resistance of tumor cells by impairing the ability to induce apoptosis. Therefore, interference with AP-2 function could increase the sensitivity of tumor cells towards therapeutic intervention.
Microcontroller-based sensor systems offer great opportunities for the implementation of safety features for potentially dangerous machinery. However, in general they are difficult to assess with regard to their reliability and failure rate. This paper describes the safety assessment of hardware and software of a new and innovative sensor system. The hardware is assessed by standardized methods according to norm EN ISO 13849-1, while the use of model checking is presented as an approach to solve the problem of validating the software.
In this paper, we introduce an optical sensor system, which is integrated into an industrial push-button. The sensor allows to classify the type of material that is in contact with the button when pressed into different material categories on the basis of the material's so called "spectral signature". An approach for a safety sensor system at circular table saws on the same base has been introduced previously on SIAS-2007. This contactless working sensor is able to distinguish reliably between skin, textiles, leather and various other kinds of materials. A typical application for this intelligent push-button is the use at possibly dangerous machines, whose operating instructions include either the prohibition or the obligation to wear gloves during the work at the machine. An exemple of machines at which no gloves are allowed are pillar drilling machines, because of the risk of getting caught in the drill chuck and being turned in by the machine. In many cases this causes very serious hand injuries. Depending on the application needs, the sensor system integrated into the push-button can be configured flexibly by software to prevent the operator from accidentally starting a machine with or without gloves, which can decrease the risk of severe accidents significantly. Especially two-hand controls are incentive to manipulation for easier handling. By equipping both push-buttons of a two-hand control with material classification properties, the user is forced to operate the controls with his bare fingers. That limitation disallows the manipulation of a two-hand control by a simple rodding device.
Changes in plasma amino acid concentrations with increasing age in patients with propionic acidemia
(2010)
Reversible logic synthesis is an emerging research topic with different application areas like low-power CMOS design, quantum- and optical computing. The key motivation behind reversible logic synthesis is the optimization of the heat dissipation problem current architectures show, by reducing it to theoretically zero [2].
This contribution presents an easy to implement 3D tracking approach that works with a single standard webcam. We describe the algorithm and show that it is well suited for being used as an intuitive interaction method in 3D video games. The algorithm can detect and distinguish multiple objects in real-time and obtain their orientation and position relative to the camera. The trackable objects are equipped with planar patterns of five visual markers. By tracking (stereo) glasses worn by the user and adjusting the in-game camera's viewing frustum accordingly, the well-known immersive "screen as a window" effect can be achieved, even without the use of any special tracking equipment.
In an explorative study, we investigated on German schoolteachers how they use, reuse, produce and manage Open Educational Resources. The main questions in this research have been, what their motivators and barriers are in their use of Open Educational Resources, what others can learn from their Open Educational Practices, and what we can do to raise the dissemination level of OER in schools.
Eine internationale Verbreitung von OER ist u. a. davon abhängig, ob bereitstehende Inhalte an den jeweiligen Kontext angepasst werden können. Dieser Beitrag befasst sich mit studierendenspezifischen, kulturell motivierten Einflussfaktoren auf Lernsituationen, die neben u. a. inhaltlichen, technischen, didaktischen und rechtlichen Fragen für eine erfolgreiche Wiederverwendung von bereits etablierten Lernressourcen prüfend berücksichtigt werden sollten.
Heterodyne gas cell measurements at 2.9 THz using a quantum cascade laser as local oscillator
(2010)
The development of robot control programs is a complex task. Many robots are different in their electrical and mechanical structure which is also reflected in the software. Specific robot software environments support the program development, but are mainly text-based and usually applied by experts in the field with profound knowledge of the target robot. This paper presents a graphical programming environment which aims to ease the development of robot control programs. In contrast to existing graphical robot programming environments, our approach focuses on the composition of parallel action sequences. The developed environment allows to schedule independent robot actions on parallel execution lines and provides mechanism to avoid side-effects of parallel actions. The developed environment is platform-independent and based on the model-driven paradigm. The feasibility of our approach is shown by the application of the sequencer to a simulated service robot and a robot for educational purpose.
We report on submillimetre bolometer observations of the isolated neutron star RX J1856.5−3754 using the Large Apex Bolometer Camera bolometer array on the Atacama Pathfinder Experiment telescope. No cold dust continuum emission peak at the position of RX J1856.5−3754 was detected. The 3σ flux density upper limit of 5 mJy translates into a cold dust mass limit of a few earth masses. We use the new submillimetre limit, together with a previously obtained H-band limit, to constrain the presence of a gaseous, circumpulsar disc. Adopting a simple irradiated disc model, we obtain a mass accretion limit of Graphic and a maximum outer disc radius of ∼1014 cm. By examining the projected proper motion of RX J1856.5−3754, we speculate about a possible encounter of the neutron star with a dense fragment of the CrA molecular cloud a few thousand years ago.
In this paper, we present a solution how to test cultural influences on E-Learning in a global context. Based on a metadata approach, we show how specifically cultural influence factors can be determined to transfer and adapt learning environments. We present a method how those influence factors can be validated for both, to improve the dynamical meta-data specification and to be used in the development of (international) E-Learning scenarios.
This Paper presents the methodical approach and early findings of the project SEN-TAF (Technology Acceptance by the Elderly to Increase Independence). The project aims to examine the acceptance of robotic systems by elderly people and make early recommendations of necessary features those systems should contain. Based on theoretical approaches of technology acceptance and an empirical study to examine the general need of support of the elderly we developed several scenarios of robot applications. These scenarios are then visualized in animations and simulations to check the preliminary defined acceptance model. Beside these scenarios we survey several other factors which might have an impact of the overall acceptance, e.g. the appearance of the robotic systems (humanoid vs. technical appearance) and the interaction 'mode' (speaking vs. nonspeaking). In addition to these animations and simulations we survey the acceptance of the robotic dog AIBO as early placeholder for future developments in animal robotic systems which could serve as a resource against boredom.
Dawning of a new global order – An essay on global transformations from an European perspective
(2010)
This paper describes FGPA-based image combining for parallel graphics systems. The goal of our current work is to reduce network traffic and latency for increasing performance in parallel visualization systems. Initial data distribution is based on a common ethernet network whereas image combining and returning differs to traditional parallel rendering methods. Calculated sub-images are grabbed directly from the DVI-Ports for fast image compositing by a FPGA-based combiner.
In Mixed Reality (MR) Environments, the user's view is augmented with virtual, artificial objects. To visualize virtual objects, the position and orientation of the user's view or the camera is needed. Tracking of the user's viewpoint is an essential area in MR applications, especially for interaction and navigation. In present systems, the initialization is often complex. For this reason, we introduce a new method for fast initialization of markerless object tracking. This method is based on Speed Up Robust Features and paradoxically on a traditional marker-based library. Most markerless tracking algorithms can be divided into two parts: an offline and an online stage. The focus of this paper is optimization of the offline stage, which is often time-consuming.