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Die vorliegende Sammlung von Aufsätzen ist Thomas Reichmann gewidmet. Schüler, Kollegen und Weggefährten wie Ulrike Baumöl, Karlheinz Hornung, Péter Horváth, Dietmar Schön, Albrecht Deyhle, Jürgen Weber, Laurenz Lachnit, Horst Wildemann und andere zeigen, was ein erfolgreiches Controlling heute ausmacht. Aufbauend auf einer kurzen Darstellung der Meilensteine des Controllings werden mit der systemgestützten Controlling-Konzeption, Kennzahlen und Kennzahlensysteme, dem Controlling in kleinen und mittleren Unternehmen, ausgewählten länder- und branchenspezifischen Aspekten des Controllings sowie dem Einfluss von Corporate Governance auf das Controlling von Konzernen wesentliche Facetten einer erfolgsorientierten Unternehmenssteuerung dargestellt. Das Werk richtet sich gleichermaßen an Wissenschaft und Controllingpraxis. Es zeigt wesentliche Entwicklungsperspektiven des Controllings in Theorie und Praxis sowie seine organisatorische Verbindung zur IT auf.
Das Informationsmanagement steht im Spannungsfeld zwischen betriebswirtschaftlichen und technischen Herausforderungen. Aktuelle Themen wie Digitalisierung, Big Data und die sich hieraus entwickelnden disruptiven Geschäftsmodelle spiegeln sich in starken Veränderungen wieder, sowohl in der Theorie, als auch in der Praxis. Die Schriftenreihe „Informationsmanagement in Theorie und Praxis“ greift diese Themen auf, sowohl in der Forschung in Form herausragender Dissertationen, als auch in der Umsetzung durch exzellente Masterarbeiten.
Wissen schmeckt
(2018)
Wie kocht ein Physiker seine Pasta „al dente“? Welche sensorischen Wahrnehmungen gibt es, wenn wir etwas Leckeres essen? Hat gesunde Ernährung immer etwas mit Verzicht zu tun? Schmeckt Essen besser, während wir Musik hören? Was hilft beim „Männerschnupfen“ wirklich? Und hat die Digitalisierung mittlerweile auch die Küche erobert? Diese und viele weitere Fragen beantworten Wissenschaftler aus den jeweiligen Fachbereichen und stellen dazu jeweils ein passendes Rezept vor, um das Forschungsthema einer breiten Zielgruppe im wahrsten Sinne des Wortes schmackhaft zu machen. Abgerundet wird dieses Menü aus Wissenschaft und kulinarischen Köstlichkeiten mit einer Weinempfehlung von Hendrik Thoma und einem Wissenshäppchen vom „Leckerwisser“.
Zu jedem Beitrag kann über einen QR-Code ein Video abgerufen werden, in dem sich Argang Ghadiri mit dem Beitragsautor über dessen Wissenschaftsgebiet unterhält. Dabei wird das im Beitrag vorgestellte Rezept gekocht.
Nachhaltiges Wirtschaften ist eine Zukunftsaufgabe, der sich das Buch aus verschiedenen Perspektiven widmet. Im Mittelpunkt steht dabei die Frage, wie die Wettbewerbsfähigkeit unseres Landes erhalten, gestärkt und damit die Zukunftsperspektiven der nächsten Generation gesichert werden können. Behandelt werden darüber hinaus u. a. Fragen nach den ethisch sinnvollen Verankerungsmöglichkeiten von Nachhaltigkeit im Unternehmen und in der Gesellschaft, nach der rechtlichen Unterstützung des globalen nachhaltigen Wirtschaftens, nach den Instrumenten für zukünftige Führungskräfte und den Nutzungsmöglichkeiten von Innovationen für ein nachhaltiges Wachstum, nach den Messungs- und Steuerungsmöglichkeiten von Nachhaltigkeit sowie nach der Perspektive des nachhaltigen Controlling im Nachfolgeprozess. Zusätzlich zur Erörterung praktischer Erfahrungen in Organisationen bilden die nachhaltige Entwicklung der Finanzwirtschaft und die Auswirkungen der Digitalisierung auf die Immobilienbranche weitere thematische Schwerpunkte.
Ein Gesundheitssystem, das auf einem erreichten medizin-technischen Stand verharrt, sich nicht mehr weiterentwickelt und damit auch keinen Zugriff auf innovative Versorgungsansätze und -strukturen erlaubt, wird sicherlich rasch in öffentliche Kritik geraten. Versorgungs- und Therapieinnovationen sind stets willkommen, wenn sich höherer Nutzen und zumindest unveränderte Kosten zeigen. Die beiden Arbeiten dieses Bandes diskutieren die aktuellen Finanzierungsregeln für Krankenhäuser und regen mit einem Vorschlag für einen innovationsbezogenen Performance Measurement-Ansatz zu weiterer Forschung in diesem Feld an.
Möchten Sie einen umfassenden Überblick über die Teilgebiete der Allgemeinen Betriebswirtschaftslehre bekommen? Dieses Buch hilft Ihnen dabei! Ausgewiesene Experten ihres Fachs erklären Ihnen in verständlicher Sprache und mit anschaulichen Beispielen alles, was Sie wissen müssen von der Materialwirtschaft über die Produktion und Logistik bis hin zum Marketing. Auch alle wichtigen Themen der Investition und Finanzierung, des internen und externen Rechnungswesens und der Unternehmensführung und -organisation werden auf fast 1000 Seiten ausführlich behandelt. (Verlagsangaben)
Welcome to the first edition of the Handbook for Applied Teaching and Learning designed primarily for educators, administrators, and students interested in applied teaching and entrepreneurial education. This handbook documents some of the outcomes of a very fruitful German-African collaboration among higher education institutions in the field of entrepreneurial education which was funded by the German Academic Exchange Service (DAAD) and the German Ministry of Economic Cooperation and Development (BMZ).
Science Track FrOSCon 2016
(2018)
Im Jahre 2015 feierte die Free and Open Source Software Conference ihr 10 Jähriges Bestehen. Entstanden aus einer Idee von Studierenden, wissenschaftlichen Mitarbeitern und Professoren des Fachbereichs Informatik entwickelte sich eine der wichtigsten Konferenzen im Bereich der freien und quelloffenen Software in Deutschland.
This Handbook of Applied Marketing and Personnel Services is part of the project "German-African University Partnership Platform for the Development of Entrepreneurship and SMEs", financed by the German Federal Ministry of Economic Cooperation and Development (BMZ) and the German Academic Exchange Service (DAAD), and jointly conducted by Bonn-Rhein-Sieg University of Applied Sciences, University of Cape Coast in Ghana and University of Nairobi in Kenya.
TREE Jahresbericht 2017
(2018)
Knapp fünf Jahre nach Gründung als Fachbereichsinstitut und zwei Jahre nach Verankerung als zentrale wissenschaftliche Einrichtung der Hochschule präsentieren wir - nicht ganz ohne Stolz - den ersten Jahresbericht des Instituts TREE. Er soll in seiner Breite als auch in seiner Tiefe die Stärken unserer gemeinschaftlichen Anstrengungen im Forschungsfeld der nachhaltigen Technologien aufzeigen: interdisziplinär, forschungsstark, nachwuchsfördernd und gesellschaftszugewandt. TREE ist weiterhin ein im Aufbruch begriffenes Institut, aber gerade das Jahr 2017 zeigt auch, dass wir uns schon in der Wissenschaftslandkarte einen Namen machen konnten: nach NaWETec konnte mit dem Themenkomplex "Effiziente Transportalternativen" ein zweiter Forschungsschwerpunkt drittmittelgefördert etabliert werden. Erste Promotionen im Rahmen des TREE konnten erfolgreich abgeschlossen und interessante Nachwuchswissenschaftler für "FHKarrierewege" gewonnen werden.
This book is about how computer systems might be designed to serve their users rather better. It deals with how to study the natural behaviour of users to see how computer systems might best help them, and how one might also involve them in the design of computer systems that will assist them in their everyday practices.
The design of an efficient digital circuit in term of low-power has become a very challenging issue. For this reason, low-power digital circuit design is a topic addressed in electrical and computer engineering curricula, but it also requires practical experiments in a laboratory. This PhD research investigates a novel approach, the low-power design laboratory system by developing a new technical and pedagogical system. The low-power design laboratory system is composed of two types of laboratories: the on-site (hands-on) laboratory and the remote laboratory. It has been developed at the Bonn-Rhine-Sieg University of Applied Sciences to teach low-power techniques in the laboratory. Additionally, this thesis contributes a suggestion on how the learning objectives can be complemented by developing a remote system in order to improve the teaching process of the low-power digital circuit design. This laboratory system enables online experiments that can be performed using physical instruments and obtaining real data via the internet. The laboratory experiments use a Field Programmable Gate Array (FPGA) as a design platform for circuit implementation by students and use image processing as an application for teaching low-power techniques.
This thesis presents the instructions for the low-power design experiments which use a top-down hierarchical design methodology. The engineering student designs his/her algorithm with a high level of abstraction and the experimental results are obtained and measured at a low level (hardware) so that more information is available to correctly estimate the power dissipation such as specification, latency, thermal effect, and technology used. Power dissipation of the digital system is influenced by specification, design, technology used, as well as operating temperature. Digital circuit designers can observe the most influential factors in power dissipation during the laboratory exercises in the on-site system and then use the remote system to supplement investigating the other factors. Furthermore, the remote system has obvious benefits such as developing learning outcomes, facilitating new teaching methods, reducing costs and maintenance, cost-saving by reducing the numbers of instructors, saving instructor time and simplifying their tasks, facilitating equipment sharing, improving reliability, and finally providing flexibility of usage the laboratories.
This paper investigates how learning objectives can be complemented by employing a remote system to improve teaching low-power digital circuits design. The low-power design laboratory system that has been developed at the Bonn-Rhine-Sieg University of Applied Sciences is composed of two laboratory types: the on-site (hands-on) and the remote laboratories to teach low-power techniques with laboratory exercises. This laboratory system enables online experiments that can be performed using physical instruments and obtaining real data. Digital circuit designers can observe the most influential factors in power dissipation during laboratory exercises in the on-site system and then use the remote laboratory to supplement investigating other factors. This contribution describes teaching activities performed during the Summer Semester 2015 using only the on-site system, and during the Summer Semester 2016 using the on-site and the remote systems. The assessment studies the achieved learning objectives, evaluates the laboratory reports with and without the support of the remote system, and analyses the students' use of the remote system. The assessment and the students' opinions provide positive feedback on this approach and verify that the remote laboratory system is a successful and effective complementary learning tool for remotely reusing the on-site laboratory and achieving additional learning objectives that cover most conceptual theories in low-power digital circuits design.
For many different applications, current information about the bandwidth-related metrics of the utilized connection is very useful as they directly impact the performance of throughput sensitive applications such as streaming servers, IPTV and VoIP applications. In literature, several tools have been proposed to estimate major bandwidth-related metrics such as capacity, available bandwidth and achievable throughput. The vast majority of these tools fall into one of Packet Pair (PP), Variable Packet Size (VPS), Self-Loading of Periodic Streams (SLoPS) or Throughput approaches. In this study, seven popular bandwidth estimation tools including nettimer, pathrate, pathchar, pchar, clink, pathload and iperf belonging to these four well-known estimation techniques are presented and experimentally evaluated in a controlled testbed environment. Differently from the rest of studies in literature, all tools have been uniformly classified and evaluated according to an objective and sophisticated classification and evaluation scheme. The performance comparison of the tools incorporates not only the estimation accuracy but also the probing time and overhead caused.
Multidisciplinary, multicultural, and multitasking has taken center stage in the global educational debate. Globalization and improvement in communication have affected the way organisations operate and hence influenced whom they hire. Today, it is common practice to work with people from diverse backgrounds and it requires competencies that go beyond general project management. Intercultural awareness, networking in different global communities, and learning to develop specific communication strategies for different stakeholders is all part of the package of skills and competencies that are required in today's interconnected world. This has indirect implication on the nature of skills and competencies institutions/universities must equip their students with to enable them to compete successfully in the working world.
Conclusion
(2018)
There is a paradigm shift from traditional content-based education and training to competencybased and practice-oriented training. This shift has occurred because practice-oriented teaching has been found to produce a training outcome that is industry focused, generating the relevant occupational standards. Competency-based training program often comprises of modules broken into segments called learning outcomes. These learning outcomes are based on criteria set by industry and assessment is designed to ensure students become competent in their respective areas of specialization.
Estimation of Prediction Uncertainty for Semantic Scene Labeling Using Bayesian Approximation
(2018)
With the advancement in technology, autonomous and assisted driving are close to being reality. A key component of such systems is the understanding of the surrounding environment. This understanding about the environment can be attained by performing semantic labeling of the driving scenes. Existing deep learning based models have been developed over the years that outperform classical image processing algorithms for the task of semantic labeling. However, the existing models only produce semantic predictions and do not provide a measure of uncertainty about the predictions. Hence, this work focuses on developing a deep learning based semantic labeling model that can produce semantic predictions and their corresponding uncertainties. Autonomous driving needs a real-time operating model, however the Full Resolution Residual Network (FRRN) [4] architecture, which is found as the best performing architecture during literature search, is not able to satisfy this condition. Hence, a small network, similar to FRRN, has been developed and used in this work. Based on the work of [13], the developed network is then extended by adding dropout layers and the dropouts are used during testing to perform approximate Bayesian inference. The existing works on uncertainties, do not have quantitative metrics to evaluate the quality of uncertainties estimated by a model. Hence, the area under curve (AUC) of the receiver operating characteristic (ROC) curves is proposed and used as an evaluation metric in this work. Further, a comparative analysis about the influence of dropout layer position, drop probability and the number of samples, on the quality of uncertainty estimation is performed. Finally, based on the insights gained from the analysis, a model with optimal configuration of dropout is developed. It is then evaluated on the Cityscape dataset and shown to be outperforming the baseline model with an AUC-ROC of about 90%, while the latter having AUC-ROC of about 80%.
Digitalisierung für kleinere und mittlere Unternehmen (KMU): Anforderungen an das IT-Management
(2018)
Ohne Steuerung des IT-Bereiches nach geschäftsorientierten Grundsätzen sind Projekte zur Digitalen Transformation überhaupt nicht möglich. Der vorliegende Beitrag beschäftigt sich mit den Anforderungen an das IT-Management von kleineren und mittleren Unternehmen (KMU) bei der Steuerung des IT-Bereiches. Anhand einer empirischen Erhebung wird die Situation im IT-Management von kleineren und mittleren Unternehmen analysiert. Anschließend wird auf Basis der ermittelten Bedarfe ein kompaktes Konzept entwickelt, mit dem das IT-Management zielgerichtet die IT-Governance in solchen Unternehmen ausüben kann.
Sind kleinere und mittlere Unternehmen (KMU) bereits auf die Digitale Transformation vorbereitet?
(2018)
Eine von den Autoren durchgeführte Untersuchung konnte deutliche Indizien dafür ausmachen, dass viele kleinere und mittlere Unternehmen (KMU) aktuell noch keine ausreichende Reife zur Digitalen Transformation haben. Zur Lösung des Problems wird vorgeschlagen, ein agiles IT-Management-Konzept zu entwickeln, um den IT-Bereich dynamisch und ohne formalen Ballast des klassischen IT-Managements zu steuern.
Renewable resources gain increasing interest as source for environmentally benign biomaterials, such as drug encapsulation/release compounds, and scaffolds for tissue engineering in regenerative medicine. Being the second largest naturally abundant polymer, the interest in lignin valorization for biomedical utilization is rapidly growing. Depending on resource and isolation procedure, lignin shows specific antioxidant and antimicrobial activity. Today, efforts in research and industry are directed toward lignin utilization as renewable macromolecular building block for the preparation of polymeric drug encapsulation and scaffold materials. Within the last five years, remarkable progress has been made in isolation, functionalization and modification of lignin and lignin-derived compounds. However, literature so far mainly focuses lignin-derived fuels, lubricants and resins. The purpose of this review is to summarize the current state of the art and to highlight the most important results in the field of lignin-based materials for potential use in biomedicine (reported in 2014–2018). Special focus is drawn on lignin-derived nanomaterials for drug encapsulation and release as well as lignin hybrid materials used as scaffolds for guided bone regeneration in stem cell-based therapies.
Antioxidant activity is an essential feature required for oxygen-sensitive merchandise and goods, such as food and corresponding packaging as well as materials used in cosmetics and biomedicine. For example, vanillin, one of the most prominent antioxidants, is fabricated from lignin, the second most abundant natural polymer in the world. Antioxidant potential is primarily related to the termination of oxidation propagation reactions through hydrogen transfer. The application of technical lignin as a natural antioxidant has not yet been implemented in the industrial sector, mainly due to the complex heterogeneous structure and polydispersity of lignin. Thus, current research focuses on various isolation and purification strategies to improve the compatibility of lignin material with substrates and enhancing its stabilizing effect.
Antioxidant activity is an essential aspect of oxygen-sensitive merchandise and goods, such as food and corresponding packaging, cosmetics, and biomedicine. Technical lignin has not yet been applied as a natural antioxidant, mainly due to the complex heterogeneous structure and polydispersity of lignin. This report presents antioxidant capacity studies completed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The influence of purification on lignin structure and activity was investigated. The purification procedure showed that double-fold selective extraction is the most efficient (confirmed by ultraviolet-visible (UV/Vis), Fourier transform infrared (FTIR), heteronuclear single quantum coherence (HSQC) and 31P nuclear magnetic resonance spectroscopy, size exclusion chromatography, and X-ray diffraction), resulting in fractions of very narrow polydispersity (3.2⁻1.6), up to four distinct absorption bands in UV/Vis spectroscopy. Due to differential scanning calorimetry measurements, the glass transition temperature increased from 123 to 185 °C for the purest fraction. Antioxidant capacity is discussed regarding the biomass source, pulping process, and degree of purification. Lignin obtained from industrial black liquor are compared with beech wood samples: antioxidant activity (DPPH inhibition) of kraft lignin fractions were 62⁻68%, whereas beech and spruce/pine-mixed lignin showed values of 42% and 64%, respectively. Total phenol content (TPC) of the isolated kraft lignin fractions varied between 26 and 35%, whereas beech and spruce/pine lignin were 33% and 34%, respectively. Storage decreased the TPC values but increased the DPPH inhibition.
The main objective of this chapter is to explore the lignocellulose feedstock (LCF) biorefinery for industrial usage according to green chemistry principles. In particular, the isolation and valorization of lignin as one of the most interesting intermediates of LCF biorefineries is discussed, including lignin isolation, purification, and structure analysis. Structure elucidation involves various chromatographic, spectroscopic, microscopic, and thermochemical methods. Thus, basic structure–property relationships regarding the influence of biomass source and isolation process on lignin amount, constitution, and 3D structure are highlighted. Furthermore, storage effects on lignin structure and degradation effects are presented. Finally, potential applications are discussed, including novel lignin-based hydrogels, composite compounds (hybrids), and nanomaterials. Focus is drawn to antioxidant and antimicrobial activity of lignin for applications in packaging and biomedicine, that is, biomaterials for drug release and tissue engineering.
Once aberrantly activated, the Wnt/βcatenin pathway may result in uncontrolled proliferation and eventually cancer. Efforts to counter and inhibit this pathway are mainly directed against βcatenin, as it serves a role on the cytoplasm and the nucleus. In addition, speciallygenerated lymphocytes are recruited for the purpose of treating liver cancer. Peripheral blood mononuclear lymphocytes are expanded by the timely addition of interferon γ, interleukin (IL)1β, IL2 and anticluster of differentiation 3 antibody. The resulting cells are called cytokineinduced killer (CIK) cells. The present study utilised these cells and combine them with drugs inhibiting the Wnt pathway in order to examine whether this resulted in an improvement in the killing ability of CIK cells against liver cancer cells. Drugs including ethacrynic acid (EA) and ciclopirox olamine (CPX) were determined to be suitable candidates, as determined by previous studies. Drugs were administered on their own and combined with CIK cells and then a cell viability assay was performed. These results suggest that EAtreated cells demonstrated apoptosis and were significantly affected compared with untreated cells. Unlike EA, CPX killed normal and cancerous cells even at low concentrations. Subsequent to combining EA with CIK cells, the potency of killing was increased and a greater number of cells died, which proves a synergistic action. In summary, EA may be used as an antihepatocellular carcinoma drug, while CPX possesses a high toxicity to cancerous as well as to normal cells. It was proposed that EA should be integrated into present therapeutic methods for cancer.
BWL-Formeln für Dummies
(2018)
Können Sie sich auch Formeln so schlecht merken? Das ist mit diesem handlichen Nachschlagewerk auch gar nicht mehr nötig! Der Autor des Bestsellers "BWL für Dummies" Tobias Amely hat für Sie die wichtigsten BWL-Formeln zusammengestellt. Zu jeder Formel finden Sie auch gleich ein anschauliches Beispiel, wie sie eingesetzt wird und eine Erklärung, wofür man sie eigentlich braucht. "BWL-Formeln für Dummies" ist also viel mehr als eine reine Auflistung von Formeln.
BWL kompakt für Dummies
(2018)
"BWL kompakt für Dummies" bietet Ihnen eine verständliche Einführung in die Betriebswirtschaftslehre, egal ob Sie sie für die Aus- oder Weiterbildung brauchen oder sich einfach schlau machen wollen. Tobias Amely stellt Ihnen die wesentlichen Elemente und Grundbegriffe der Betriebswirtschaftslehre vor und zeigt die Bezüge zur Unternehmenspraxis auf: Materialwirtschaft, Leistungsbereitstellung und Produktion, Marketing, Investition und Finanzierung, Unternehmensorganisation und -führung, Rechnungswesen und Controlling.
Investition und Finanzierung sind wichtige Themen in der Unternehmenspraxis und im Studium der Betriebswirtschaftslehre. Dieses Buch führt Sie anhand anschaulicher Beispiele in die Grundlagen des Themas ein und zeigt die Ziele finanzwirtschaftlichen Handelns auf. Tobias Amely und Christine Immenkötter zeigen Ihnen die Grundzüge der Finanzwirtschaft und stellen Ihnen die wichtigsten Instrumente sowohl der Außen- und Innenfinanzierung als auch des Finanzmanagements vor. Lernen Sie die statische und dynamische Investitionsrechnung kennen und erfahren Sie, was man über Investitionen in Wertpapiere wissen muss. So liefert Ihnen dieses Buch im bewährten ... für Dummies-Stil einen guten und leicht verständlichen Überblick über alle wichtigen Themen der Investition und Finanzierung. (Verlagsangaben)
Umwelt: Technologien, um die Folgen des Klimawandels zu begrenzen, gibt es. Die soziale und politische Dimension ist der Hemmschuh, so dass sie teils nur zögernd zum Einsatz kommen.
Die Redaktion der VDI nachrichten betreute drei Studierende, die aktuell von jedem Vortrag einen Artikel für unser Ingenieurportal www.ingenieur.de schrieben sowie eine Meldung für die VDI-nachrichten-E-Paper-App. Dieser Artikel ist das Resümee der drei zur Ringvorlesung, aber keine inhaltlich komplette Zusammenfassung. Alle Artikel lesen Sie online unter: www.ingenieur.de/Ringvorlesung2018
ICT has traditionally been a hostile territory for women. In information societies, this implies a drastic reduction in opportunities and autonomy for women. In emergent economies, the situation is even worse due to women’s subordinate status in society and little research regarding the intersection between gender and the digital divide. Such is the case in Latin America. In light of this, the purpose of this essay is to introduce a first comprehensive review of the few studies made in Latin America, against the background of the history of women’s digital exclusion. Based on a review of literature, we identify the main causes for women’s digital exclusion in the region and talk about the prospects for development of gender policies in the BRICS countries (Brazil, Russia, India, China and South Africa). We conclude that what this group of countries may achieve in regard to gender equality, will mark the future of the world. The aim of this essay is to make a call for the creation of inter - national research networks and propose the BRICS as host for these efforts, as they combine characteristics that will make them leaders of change in vast regions.
Currently, a multitude of studies, whitepapers and roadmaps claim to predict the future of robotics and automation. Unfortunately, all of them are to some extent limited in their scope, by design and/or are biased by some particular interests. In most cases this is not even by intention, but the fact, that the euRobotics Multiannual Roadmap and Strategic Research Agenda only focus on the European robotics community limits it to a certain field of view. The same applies for the U.S. Robotics Roadmap and other documents. In this paper, we suggest the methodology for a Delphi-Study – a guided, unbiased and holistic approach based on neutral interviews with internationally well renowned experts. The necessity for a Delphi-Study has already been laid out by the IEEE RAS Industries Activities Board in the IEEE RAM Magazine [6].
Analytical redundancy relations are fundamental in model-based fault detection and isolation. Their numerical evaluation yields a residual that may serve as a fault indicator. Considering switching linear time-invariant system models that use ideal switches, it is shown that analytical redundancy relations can be systematically deduced from a diagnostic bond graph with fixed causalities that hold for all modes of operation. Moreover, as to a faultless system, the presented bond graph–based approach enables to deduce a unique implicit state equation with coefficients that are functions of the discrete switch states. Devices or phenomena with fast state transitions, for example, electronic diodes and transistors, clutches, or hard mechanical stops are often represented by ideal switches which give rise to variable causalities. However, in the presented approach, fixed causalities are assigned only once to a diagnostic bond graph. That is, causal strokes at switch ports in the diagnostic bond graph reflect only the switch-state configuration in a specific system mode. The actual discrete switch states are implicitly taken into account by the discrete values of the switch moduli. The presented approach starts from a diagnostic bond graph with fixed causalities and from a partitioning of the bond graph junction structure and systematically deduces a set of equations that determines the wanted residuals. Elimination steps result in analytical redundancy relations in which the states of the storage elements and the outputs of the ideal switches are unknowns. For the later two unknowns, the approach produces an implicit differential algebraic equations system. For illustration of the general matrix-based approach, an electromechanical system and two small electronic circuits are considered. Their equations are directly derived from a diagnostic bond graph by following causal paths and are reformulated so that they conform with the matrix equations obtained by the formal approach based on a partitioning of the bond graph junction structure. For one of the three mode-switching examples, a fault scenario has been simulated.
Die Digitalisierung aller Lebenswelten wird das Kauf- und Konsumverhalten von Verbrauchern stark ändern. Es zeichnet sich ab, dass Zukunftsszenarien des Smart Shopping, Smart Kitchen und Smart Cooking zunehmend real werden und sich immer stärker verzahnen. Zurzeit finden sich z. B. Bestrebungen zum digitalen Kassenzettel. Der Beitrag zeigt, dass Verbraucher sich hierdurch eine Reihe von Mehrwerten erhoffen, z. B. dass sie eine höhere Transparenz ermöglichen, indem sie Zusatzinformationen zu den Produkten bereitstellen. Ebenfalls sollen die Informationen genutzt werden, Rezeptvorschläge zu den gekauften, im Haus befindlichen Waren sowie Auskunft über den Zustand der Waren bereitzustellen. Ein weiterer Bereich stellt eine bessere Kosten- und Ernährungskontrolle dar, indem die Daten des Kassenzettels automatisch in digitale Haushaltsbücher und Ernährungs- bzw. Fitness-Apps übertragen werden können.
Here, we present a miR mechanism which is active in the nucleus and is essential for the production of intron included, C-terminal truncated and biologically active proteins, like e.g. Vim3. We exemplified this mechanism by miRs, miR-15a and miR-498, which are overexpressed in clear cell renal carcinoma or oncocytoma. Both miRs directly interact with DNA in an intronic region, leading to transcriptional stop, and therefore repress the full length version of the pre-mRNA, resulting in intron included truncated proteins (Mxi-2 and Vim3). A computational survey shows that this miR:DNA interactions mechanism may be generally involved in regulating the human transcriptome, with putative interaction sites in intronic regions for over 1000 genes. In this work, an entirely new mechanism is revealed how miRs can repress full length protein translation, resulting in C-terminal truncated proteins.
Softwarenutzung im Umbruch: Von der Software-Lizenz zum Cloudbasierten Business Process Outsourcing
(2018)
Bislang war die Rollenverteilung eindeutig geregelt: Die Beschaffung von „Standardsoftware“ war eine Aufgabe für die IT-Leitung. Im Kern war es ein Bestellprozess für Softwarelizenzen. Die Unternehmensführung (CEO) konnte sich darauf konzentrieren, die Unternehmensstrategie zu entwickeln und in diesem Zusammenhang das Budget für die IT bereitzustellen. Strategisch in der Unternehmensführung diskutiert, wurden lediglich Softwarebeschaffungsprojekte mit Einfluss auf sämtliche Unternehmensabläufe – wie z. B. die Einführung eines ERP-Systems. Die rasch zunehmende Digitalisierung verändert aber nicht nur die Arbeitsweise in den Unternehmen, sondern auch das IT-Management selbst. Aufgrund der veränderten Produktpolitik großer Softwareanbieter wie z. B. Microsoft sind zukünftige Investitionsentscheidungen über den Einsatz von Standardsoftware keine reinen Beschaffungsvorgänge mehr, sondern strategische Entscheidungen über die Auslagerungen von Prozessen (Business Process Outsourcing) und damit verbunden auch mit den zusammenhängenden Daten. Der Softwareanbieter von morgen ist ein Prozessdienstleister, der neben der Hard- und Software auch noch Teilprozesse (z. B. Kommunikation, Dokumentenmanagement) für die Unternehmen bereitstellt.
Die Digitalisierungswelle führt zu radikalen und nachhaltigen (disruptiven) Veränderungen innerhalb und außerhalb der Unternehmen. Geschäftsmodelle, Strategien, Prozesse, Organisationsstrukturen und Qualifikationsanforderungen von Mitarbeitern müssen neu ausgerichtet werden, ohne dass das laufende Geschäft zu sehr beeinträchtigt wird. Der Beitrag zeigt auf, dass die bisherigen Berufsbilder wie IT-Leiter, Chief Process Officer oder Chief Information Officer aufgrund der Veränderungen durch ein neues Berufsbild, den Chief Digital Officer, abgelöst werden. Allerdings ist die Diskussion hierzu noch nicht abgeschlossen.
This Business English course in entrepreneurship goes beyond communicative language instruction and offers a course designed to introduce students to innovative thinking, entrepreneurship and sustainable business practices. About 120 students in their first year are enrolled as part of the required foreign language module in Business Management (B.Sc.). Each week students learn new concepts and terminology in sustainable business practices while applying the material in a simulation task-based course using English as a lingua franca. It prepares students to work in an international context while offering online components for autonomous learning. This 12-14 week course is designed in a student-centered and blended learning format with a flipped classroom approach. Through a grant from the German Federal Ministry of Education and Research the “work&study project” will offer additional online materials by developing new educational apps to enhance autonomous language learning and making the app content available under the Creative Commons license. The research project focuses on offering new learning environments to enhance the opportunities for non-traditional students enrolled at Bonn-Rhein-Sieg University of Applied Sciences. This paper will focus on the development of the first apps and results of the first testing phase. It shows how game-based learning and elements of gamification were added for educational purposes to enhance teaching and learning processes that were already well established.
The curricula of all degree programs at H-BRS have many different practice-oriented activities and focus on hands-on learning. In labs and small classrooms (30–60 persons), students get a personalized learning environment which is complemented with many individual and group projects that foster collaborative work situations. There are several main areas that students learn from working with industry, local organizations or public institutions.
The most prominent education reform in Europe started in Bologna, Italy, in 1999, when the European Ministers responsible for higher education met to set the foundation for the European Higher Education Area (EHEA). The following process to reform and unify higher education and its systems in Europe is therefore known as the Bologna Process.
Telecollaborating and communicating in online contexts using English as a Lingua Franca (ELF) requires students to develop multiple literacies in addition to foreign language skills and intercultural communicative competence. This chapter looks at the intersection of technology and teaching ELF, examining mutual contributions of technologies, more specifically Web 2.0, and ELF to each other, and the challenges in designing and implementing collaboration projects across cultures. Moreover, it looks at how the development of digital competencies in ELF (DELF) can be enhanced through the implementation of Web 2.0 mediated intercultural dialogues. The detail of the research design including internet tools used, participants and tasks are also discussed. Data analysis points to a positive attitude towards telecollaboration, also providing confirmation of some of the problems identified in theoretical framework, such as different levels of personal engagement.
Technische Innovationen verändern den Alltag enorm – auch den von Journalisten. Technik-Fachjournalisten sind daher gefragt wie nie. Was sie können müssen, wie in den Medien über Digitalisierung berichtet wird und inwiefern künstliche Intelligenz (KI) Journalisten in Zukunft überflüssig machen wird, beantwortet der Medienwissenschaftler Andreas Schümchen im Gespräch mit dem "Fachjournalist".